Purpose – This study aims to examine the effect of work-life balance on employee performance with job satisfaction as a mediating variable among nurses at Sinar Kasih Purwokerto Hospital. Design/Methodology/Approach – This study employed a descriptive quantitative approach with a replication research design. Data were collected from 58 nurses using a saturated sampling technique. The collected data were analyzed using SmartPLS version 3 through mediation regression analysis to examine the direct and indirect relationships among work-life balance, job satisfaction, and employee performance. Findings – The results indicate that work-life balance has positive and significant effects on employee performance and job satisfaction. Furthermore, job satisfaction has a positive and significant effect on employee performance and significantly mediates the relationship between work-life balance and employee performance. These findings demonstrate that improving nurses’ work-life balance can enhance job satisfaction, which subsequently contributes to better employee performance. Originality/Value – This study contributes to healthcare human resource management literature by examining the mediating role of job satisfaction in the relationship between work-life balance and employee performance within a hospital setting. The novelty of this research lies in its focus on nurses at Sinar Kasih Purwokerto Hospital, providing empirical evidence on how work-life balance strategies can support employee well-being and service quality improvement. Practically, the findings suggest that healthcare organizations should strengthen work-life balance initiatives and maintain high levels of job satisfaction to improve nurse performance and overall healthcare service quality.
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