Drug information services are an integral part of good pharmacy practice and play a vital role in promoting antibiotic compliance and ensuring treatment success. This study aimed to examine the correlation between drug information services, antibiotic compliance, and patient satisfaction at Osadha Clinic, Denpasar, Bali. A cross-sectional observational study was conducted involving 105 patients, using structured questionnaires and a pharmacist’s drug information checklist. Antibiotic compliance was assessed using a 16-item yes/no questionnaire, while patient satisfaction was measured through 22 Likert-scale statements. Validity and reliability were confirmed with an r-table value of r > 0.361 (p < 0.05), and Cronbach's alpha coefficients of 0.972 for compliance and 0.881 for satisfaction. Pearson correlation analysis demonstrated a significant relationship between drug information services and antibiotic compliance (r = 0.814, p < 0.001), as well as between drug information services and patient satisfaction (r = 0.905, p < 0.001). High-quality drug information services (characterized by clarity, accuracy, and comprehensibility) significantlyenhance patient compliance and satisfaction. These findings underscore the importance of strengthening pharmaceutical care to support rational antibiotic use and improve overall healthcare outcomes.
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