<![CDATA[The transformation towards Industry 5.0 requires MSMEs to integrate technology, human orientation, and sustainability in order to strengthen regional economic growth. This study aims to analyze the MSME development model based on Industry 5.0 through the relationship between technology adoption, human resource capabilities, stakeholder collaboration, and business performance. The research uses a qualitative approach with in-depth interviews, observations, and documentation of 15 informants consisting of MSME actors, local governments, academics, and business assistants. The data is analyzed thematically through reduction, categorization, and conclusion drawn. The results show that the integration of smart technologies, competency enhancement, and business ecosystem collaboration strengthen innovation, productivity, and market expansion. The research concludes that the model is relevant as an adaptive business administration framework to support MSMEs and regional economic growth]]>
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