<![CDATA[Background: Breast cancer diagnosis and its subsequent treatments frequently trigger severe distress, anxiety, depression, and body image disturbances, these psychological morbidities and the fear of cancer recurrence remain highly prevalent. While effective psychosocial management is crucial, a recent paradigm shift emphasizes nursing-led experimental interventions that offer accessible, personalized, and holistic care to mitigate these challenges and improve patients' quality of life.Aim: To synthesize recent trends and evaluate the clinical efficacy the quality of nursing-led experimental interventions in psychosocial management for women diagnosed with breast cancer.Methods: This study search through some electronic databases (including PubMed, Science-direct, and Springer-link) up to 2026. Studies were included if they were experimental studies focusing on psychosocial interventions designed, delivered, or coordinated primarily by nurses for breast cancer patients. Data extraction and quality assessment were performed using standardized appraisal tools.Results: From 3,786 identified records, 10 studies met the inclusion criteria. The reviewed nursing-led interventions were categorized into four main groups: (1) digital and tele-nursing interventions, (2) mindfulness and somatic-based interventions, (3) brief psychosocial interventions, and (4) multi-component supportive or palliative care interventions. Overall, these nurse-led modalities demonstrated significant beneficial effects across a broad spectrum of patient outcomes. Specifically in improvements quality of life and psychosocial adjustment compared to standard care.Conclusions: Nurse-led psychosocial interventions are promising strategies to improve psychosocial outcomes in women with breast cancer, effectively reducing psychological distress and enhancing quality of life through digital, mindfulness, and multi-component approaches.Keywords: breast cancer; nurse-led intervention; psychosocial; quality of life.]]>
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