This study is motivated by the development of scientific exegesis that positions the Qur’an as a source of scientific inspiration, particularly through Al-Jawahir fi Tafsir al-Qur’an al-Karim by Tantawi Jawhari, which is widely recognized for its encyclopedic character. The main issues addressed in this study are how scientific integration is constructed in Al-Jawahir, how its encyclopedic approach can be evaluated epistemologically, and how relevant it remains in contemporary Qur’anic studies. This study aims to analyze the model of scientific integration in Al-Jawahir, identify its epistemological strengths and weaknesses, and formulate its relevance for the development of scientific exegesis today. This research employs a qualitative method using a library research approach and descriptive-critical analysis of Al-Jawahir as the primary text, supported by relevant literature on tafsir epistemology. The findings reveal that the encyclopedic character of Al-Jawahir successfully broadened the interpretation of cosmological verses and opened a productive dialogue between revelation and science. However, the dominance of scientific explanations also raises epistemological concerns, including dependence on temporal scientific theories and the potential shift from the Qur’an’s primary function as guidance. This study concludes that Al-Jawahir is best understood as a model of expansive scientific integration that still requires epistemological boundaries to preserve the Qur’an’s essential role as divine guidance.
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