Informal caregivers of patients with cancer, typically spouses, children, or siblings, provide daily care without training or pay and are therefore vulnerable to psychological distress and burnout. Brief interventions suited to their limited time remain scarcely tested in Indonesia. This study aimed to analyse changes in psychological distress and burnout after a single yoga session and to compare the magnitude of the two changes. A quasi-experimental one-group pretest-posttest design was used, involving 30 informal caregivers selected through purposive sampling at a regional public hospital in Yogyakarta. A certified instructor led one 60-minute yoga session consisting of warm-up, basic postures, breathing regulation, and relaxation. Psychological distress was measured with the total score of the DASS-21, and burnout was measured with a 12-item questionnaire adapted from the Zarit Burden Interview (ZBI). Both instruments showed very high reliability (Cronbach’s α = 0.904 for the DASS-21 and 0.944 for the burnout questionnaire). Data were analysed using the paired t-test and the Wilcoxon signed-rank test. Mean distress scores decreased from 35.00 to 27.57 (p < 0.001; dz = 1.25), while mean burnout scores decreased from 24.70 to 18.13 (p < 0.001; dz = 0.89). Distress decreased in 25 respondents with a relatively even distribution, whereas almost half of the total burnout reduction came from five respondents. A single yoga session is better positioned as a means of relieving acute distress than as a treatment for burnout, which also requires a reduction in care demands. Controlled trials with further follow-up are needed to confirm whether these changes persist.
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