Hypercholesterolemia is the leading predictor of various cardiovascular disease (CVD) which is the leading cause of death in the world. This study aims to determine whether there are any differences the incidence of hypercholesterolemia based on factors related to it in people with diabetes mellitus at Pasar Minggu Primary Health Care in 2018. This study used a cross-sectional method with a sample size of 126 respondents using consecutive sampling. Research variables studied were incidence of hypercholesterolemia, sex, duration of diabetes mellitus, family history of diabetes mellitus, smoking habit, physical activity, stress level, body fat percentage and fat intake. The results of this study showed that the prevalence of hypercholesterolemia incidence in DM patients was 56.3% with 37.1% in men and 63.7% in women. Of all independent variables studied, significant differences with statistical analysis were in sex (OR = 2.947, p = 0.009), family history (OR = 0.443, p = 0.018) and s moking habits (OR = 1,233; p = 0.038). Meanwhile, there was no significant the incidence of hypercholesterolemia differences based on duration of diabetes mellitus, physical activity, stress level, body, fat body percentage and fat intake due to p > 0.05. To conclude, there were significant differences in sex, family history of diabetes mellitus and smoking habits with hypercholesterolaemia incidence, with an increased risk of hypercholesterolemia in line with female sex, family history of DM and active smoking habits.
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