STRUCTURE ELUCIDATION OF ALKALOIDS FROM LEAVES OF Voacanga foetida (Bl.) Rolfe OF LOMBOK ISLAND

Surya Hadi (Study Program of Chemistry, Faculty of Mathematics and Natural Sciences, University of Mataram, Jl. Majapahit 62 Mataram-NTB 83125)
Dina Asnawati (Study Program of Chemistry, Faculty of Mathematics and Natural Sciences, University of Mataram, Jl. Majapahit 62 Mataram-NTB 83125)
Novi Febrianti (Study Program of Biology, Faculty of Mathematics and Natural Sciences, University of Mataram, Jl. Majapahit 62 Mataram-NTB 83125)

Indonesian Journal of Chemistry
Vol 10, No 2 (2010)

The leaves of Voacanga foetida (Bl.) Rolfe, have been used ethnomedically for the treatment of wounds, itches, and swellings particularly in Lombok island. A phytochemical study has been done to investigate chemical compounds responsible against the cause of the diseases. By separating alkaloidal fraction from the leaves was found voacristine 1 as the major alkaloidal compound, and voacangine 2 and coronaridine 3 as the minor components. The structure elucidation of the compounds was carried out on the basis of spectroscopy data. A structure revision of voacristine 1 was also reported.