6,6’-DIMETHOXY-4,4’-DIHYDROXY-3’,2’-FURANO-ISOFLAVANE, A NEW COMPOUND FROM Melochia umbellata (Houtt.) Stapf var. Degrabrata K. (Paliasa)

Erwin Erwin (Doctoral Programme in Chemistry, Post Graduate Programme, Hasanuddin University and Department of Chemistry, Mulawarman University, Kampus Gn. Kelua, 75123 Samarinda)
Alfian Noor (Department of Chemistry Hasanuddin University, Kampus UNHAS Tamalanrea, 90245 Makassar)
Nunuk Hariani Soekamto (Department of Chemistry Hasanuddin University, Kampus UNHAS Tamalanrea, 90245 Makassar)
Tjodi Harlim (Department of Chemistry Hasanuddin University, Kampus UNHAS Tamalanrea, 90245 Makassar)

Indonesian Journal of Chemistry
Vol 10, No 2 (2010)

Using data from UV, IR, 1H-NMR, 13C-NMR, dan NMR-2D analysis, a compound of 6,6'-dimethoxy-4,4'-dihydroxy-3',2'-furano-isoflavane (1) was successfully isolated from chloroform fraction of heartwood in Melochia umbellata (Houtt.) Stapf var. Degrabarata K (Paliasa). Hitherto no report of such compound found in literature. The compound however has not shown a significant bioactivity according to either brine shrimp lethality test or evaluation of anti tumor activity against leukemia murine cell (P-388).