New Prenylated Stilbenes and Antioxidant Activities of Cajanus cajan (L.) Millsp. (Pigeon pea)

Taslim Ersam (Department of Chemistry, Sepuluh Nopember Institute of Technology (ITS), Jl. Arief Rahman Hakim, Sukolilo, Surabaya 60111)
Sri Fatmawati (Department of Chemistry, Sepuluh Nopember Institute of Technology (ITS), Jl. Arief Rahman Hakim, Sukolilo, Surabaya 60111)
Dini Nur Fauzia (Department of Chemistry, Sepuluh Nopember Institute of Technology (ITS), Jl. Arief Rahman Hakim, Sukolilo, Surabaya 60111)

Indonesian Journal of Chemistry
Vol 16, No 2 (2016)

New Prenylated stilbene derivatives, 3-hydroxy-4-prenyl-5-methoxy-stilbene acid (1) and 5,4'-dihydroxy-3-methoxy-2-prenyl-stilbene (2) had been isolated from methanol extract of Cajanus cajan (L.) Millsp. (Pigeon pea), a member of family fabaceae. The aim of this present work was to evaluate its in vitro antioxidant activity using 2,2-diphenyl-1-picryhydrazyl (DPPH) radical-scavenging. Isolation of compounds was achieved by extraction (maceration) and chromatographic technique. The structures of the compounds were determined based on UV, IR, 1H-NMR and 13C-NMR spectra and also by comparing with the previously reported data. Antioxidant activities (IC50) of 1 and 2 were 413.68 μg/mL and 271.53 μg/mL, respectively.