<![CDATA[Objective: To determine the relationship of fFn levels in cervicovaginal
discharge of pregnant women who experience imminent
premature parturition with the incidence of preterm labor.
Method: The study was carried out with Analytic Observational Prospective
Cohort using cervicovaginal discharge of pregnant women
that experienced imminent premature parturition taken from the
delivery room of Obstetrics and Gynecology department dr. Saiful
Anwar Hospital, Malang as well as Bangil Hospital and Ngudi
Waluyo Wlingi Hospital. Statistical analysis was performed using the
Shapiro-Wilk test and comparison test used independent samples t
test for normal data, Mann-Whitney test if not. All analysis used SPSS
for Windows 19.0 software.
Result: Thirty two patient samples was examined, 14 patients
(43.75%) were primigravida and 18 patients (52.56%) is multigravida.
17 of these patients (53.13%) experienced aterm labor and
15 patients (46.87%) experienced preterm labor. Mann-Whitney
test of the mean fFN levels between the aterm group (13.01 ± 7.57
ng/ml) and the preterm group (56.29 ± 27.77 ng/ml) showed a significant
difference (p-value = 0.000 > 0.05). Moreover, Spearman’s
Rho correlation test also showed a strong correlation between fFN
level and incidence of preterm labor (R = 0.797, p < 0.05).
Conclusion: fFN levels is significantly increase in cervicovaginal discharge
from pregnant women with imminent premature parturition
who experience preterm labor than pregnant women who experience
aterm labor. Therefore, this result suggests that fFN has potential
ability to become useful modality in preterm labor diagnosis.
[Indones J Obstet Gynecol 2016; 1: 8-14]
Keywords: cervicovaginal discharge, fFN, imminent premature parturition,
preterm labor]]>
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