JSFK (Jurnal Sains Farmasi & Klinis)
Vol 4, No 1 (2017): J Sains Farm Klin 4(1), November 2017

Audit Secara Prospektif terhadap Antimicrobial Stewardship Program pada Pasien Kanker Payudara di RSUP Dr. M. Djamil Padang

Yelly Oktavia Sari (Fakultas Farmasi Universitas Andalas)
Rustini Rustini (Fakultas Farmasi Universitas Andalas)
Diva Diana (Fakultas Farmasi Universitas Andalas)
Telsa Dwiana Hapsari (Fakultas Farmasi Universitas Andalas)



Article Info

Publish Date
15 Dec 2017

Abstract

Surgery has been used as part of the treatment of breast cancer, but surgery has a potential risk of infection due to the effect of normal flora on the body and air in the ward environment. The decrease of antibiotics effectiveness is caused by bacterial resistance to antibiotics. The purpose of this study was to find out the pattern of bacteria, antibiotic sensitivity patterns and patterns of antibiotic use among breast cancer patients in the surgery ward Hospital M. Djamil Padang. An observational prospective study design was performed in this study, whereby data was collected from the medical records of patients admitted to the surgery wards of Hospital Dr. M. Djamil Padang from April – September 2017. Results showed the bacterial identification in patients were Staphylococcus aureus and Klebsiella sp. while from the air were found Staphylococcus aureus, Staphylococcus epidermidis and Klebsiella sp. Based on the sensitivity pattern on surgical wounds during April-May 2017 reported amoxicillin/ clavulanic acid and meropenem were good (>80%) while on August-September 2017 was meropenem. Airborne sensitivity patterns result during April-May 2017 were not found, while on August-September 2017 gentamicin, ciprofloxacin and meropenem were good (>80%). Among 32 patients admitted during study period only 7 patients who fulfilled the inclusion criteria. The most common antibiotic used was ceftriaxone 7 (77,8%). The evaluation of the rationale use of antibiotics were 6 (66.7%) appropriate medication, 9 (100%) appropriate dosage, 7 (77.8%) appropriate time duration, 9 (100%) appropriate route, 7 (100%) appropriate patient, 4 (45,1%) appropriate indication and potentially drug interaction 1 (14,28%) as a minor potency.

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Journal Info

Abbrev

jsfk

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Description

Jurnal Sains Farmasi & Klinis (J Sains Farm Klin) adalah jurnal ilmiah di bidang kefarmasian yang diterbitkan oleh Fakultas Farmasi Universitas Andalas bekerjasama dengan lembaga profesi "Ikatan Apoteker Indonesia" (IAI) daerah Sumatera Barat sejak tahun ...