Journal of Epidemiology and Public Health
Vol 4, No 3 (2019)

The Effect of Obesity, Oral Contraceptive and Passive Smoking on the Risk of Cervical Cancer

Arfailasufandi, Roiela (Unknown)
Mudigdo, Ambar (Unknown)
Sudiyanto, Aris (Unknown)



Article Info

Publish Date
16 Jul 2019

Abstract

Background: Studies have investigated the effects of obesity on cancer development. However, the relationship between obesity and cervical cancer risk is unclear. This study aimed to determine the effect of obesity, oral contraceptive and passive smoking on the risk of cervical cancer.Subjects and Method: A case-control study was conducted at Dr. Moewardi Hospital, from October to December 2018. A sample of 200 patients was selected by fixed disease sampling, consisting of 100 cervical cancer patients and 100 noncervical cancer patients. The dependent variable was cervical cancer. The independent variables were obesity, oral contraceptive use, smoking exposure, parity, age at first sexual intercourse, and family history. The data were obtained from the medical record. The data were analyzed by multiple logistic regression.Results:The risk of cervical cancer increased with obesity (OR= 6.83; 95%CI= 2.44 to 19.17; p<0.001), cigarette smoke exposure (OR= 12.57; 95% CI= 4.59 to 34.41; p<0.001),oral contra­ceptive use (OR= 3.43; 95%CI= 1.27 to 9.25; p= 0.015), parity (OR= 3.94; 95%CI= 1.47 to 10.59; p= 0.006), and family history (OR= 5.63; 95%CI= 1.94 to 16.34; p= 0.001).The risk of cervical cancer decreased with delayed menarche (OR= 0.24; 95%CI= 0.09 to 0.68; p= 0.007) and delayed age at first sexual intercourse (OR= 0.21; 95%CI= 0.86 to 0.53; p= 0.001).Conclusion: The risk of cervical cancer increases with obesity, oral contraceptive use, smoking exposure, parity, and family history. The risk of cervical cancer decreases with delayed menarche and delayed age at first sexual intercourse.Keywords: obesity, oral contraception, smoking exposure, cervical cancerCorrespondence: Roiela Arfailasufandi. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami No. 36 A, Surakarta 57126, Central Java, Indonesia. Email: andi_suf@ymail.com. Journal of Epidemiology and Public Health (2019), 4(3): 189-197https://doi.org/10.26911/jepublichealth.2019.04.03.06

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Journal Info

Abbrev

jepublichealth

Publisher

Subject

Public Health

Description

Background: Increased blood pressure for a long time can increase the risk of kidney failure, co­ronary heart disease, brain damage, and other di­seases. In 2019, it is estimated that hyper­tens­ion is experienced by 1.13 billion people in the world with most (two thirds) living in low and ...