Paediatrica Indonesiana
Vol 53 No 6 (2013): November 2013

Proteinuria and malaria parasite counts in children

Mahrani Lubis (Department of Child Health, University of North Sumatera Medical School, H. Adam Malik Hospital)
Rusdidjas Rusdidjas (Department of Child Health, University of North Sumatera Medical School, H. Adam Malik Hospital)
Rafita Ramayati (Department of Child Health, University of North Sumatera Medical School, H. Adam Malik Hospital)
Oke Rina Ramayani (Department of Child Health, University of North Sumatera Medical School, H. Adam Malik Hospital)
Rosmayanti S Siregar (Department of Child Health, University of North Sumatera Medical School, H. Adam Malik Hospital)
Supriatmo Supriatmo (Department of Child Health, University of North Sumatera Medical School, H. Adam Malik Hospital)



Article Info

Publish Date
30 Dec 2013

Abstract

Background Malaria-induced proteinuria has been observed insevere cases of malaria. Few studies have been done to assess foran association between proteinuria and malaria parasite countsbefore the disease becomes severe.Objective To investigate a possible association between proteinuriaand malaria parasite counts in children .Methods A cross-sectional study was conducted on school-agedchildren in Panyabungan, Mandailing Natal, between Septemberto November 2010. Malaria was diagnosed by microscopicexamination of peripheral blood smears. Children with malariaunderwent proteinuria t ests by urine dipstick method. Anassociation between proteinuria and malaria parasite counts wasanalyzed using linear regression test.Results Of 181 participants with Plasmodium fak:iparum malaria,53.6% were female and had a mean age of 7.8 years. Subjects'nutritional status were as follows: 50.8% normoweight, 28.2%mild malnutrition, 3 .3% moderate malnutrition, and 17. 7% severemalnutrition. Clinical manifestations showed 36.5% suffered fromsubfebrile temperatures and 29.8% had pallor. Proteinuria occurredin 45.9% participants and there was a weak association betweenproteinuria and malaria parasite counts (raa .261, Paa .0001).Conclusion There is a weak association between proteinuria andmalaria parasite counts in children.

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Journal Info

Abbrev

paediatrica-indonesiana

Publisher

Subject

Health Professions Medicine & Pharmacology

Description

Paediatrica Indonesiana is a medical journal devoted to the health, in a broad sense, affecting fetuses, infants, children, and adolescents, belonged to the Indonesian Pediatric Society. Its publications are directed to pediatricians and other medical practitioners or researchers at all levels of ...