Oceana Biomedicina Journal
Vol 1, No 1 (2018): Oceana Biomedicina Journal

Ethanolic Extract of The Graptophyllum Pictum Griff Leaves as Antipyretic agent to Male White Rat

Rikomah, Setya Enti ( Akademi Farmasi Yayasan Al-Fatah Bengkulu)
Lestari, Gina ( Akademi Farmasi Yayasan Al-Fatah Bengkulu)
Winanti, Juwita ( Akademi Farmasi Yayasan Al-Fatah Bengkulu)



Article Info

Publish Date
12 Jan 2018

Abstract

Utilization of plants as traditional medicinal are still always be  used by people in Indonesian. Especially in rural areas that  still rich with variety of plants. Plants  of black pudding leaves (Graptophyllum pictum Griff) are one that efficacious for treating various of diseases. The content of  flavonoid  in the black pudding leaves have  antipyretic effect, analgesic and anti-inflammatory. This research aims to find  out  whether the black pudding leaves have  antipyretic effect or not. This research  used the induction method  of vaccineDPT-Hb 0.022 / 20 gr a white rat as stimulant fever. Positive control with paracetamol 1.3 mg / 20 gram a white rat, negative control with Na CMC 0.5 ml / 20 grams a white rat, first extract test of black pudding leaves  0.8 mg / 20 gram a white rat, second extract test of  black pudding leaves 1.6 / 20 gram a white rat, and third extract test  of black pudding leaves 3.2 / 20 gram a white rat. The results of research showed that ethanol extract of black pudding leaves if it’s looked from  statistic result of SPSS 16 program , it doesn’t  show out of any effect as antipyretic effect because  the significant value  is P> 0.05.Keywords: Antipyretic, DPT vaccine Hb, (Graptophyllum pictum)

Copyrights © 2018






Journal Info

Abbrev

journal

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Dentistry Medicine & Pharmacology Nursing Public Health

Description

Oceana Biomedicina Journal is an open access journal of health and medicine.Specifically, the journal focuses on marine medicine, hyperbaric medicine and health, medicine on ships, harbor health, maritime and coastal health, medicolegal studies related to ships, ports and districts, maritime/coastal ...