Garuda - Garba Rujukan Digital

Article Per Year (5 Year)

All

Oceana Biomedicina Journal

journal
Website

Published by Universitas Hang Tuah

ISSN : - EISSN : 26140519 DOI : https://doi.org/10.30649/obj.v5i1.67

Core Subject : Health, Science,

Biochemistry, Genetics & Molecular Biology Dentistry Medicine & Pharmacology Nursing Public Health

Oceana Biomedicina Journal is an open access journal of health and medicine.Specifically, the journal focuses on marine medicine, hyperbaric medicine and health, medicine on ships, harbor health, maritime and coastal health, medicolegal studies related to ships, ports and districts, maritime/coastal communities and fishermen, epidemiological aspects of diseases, disabilities and disorders that occur on ships and affect boat workers, ports and maritime zones, coastal areas, fishermen communities and their families, including pharmacological and non-pharmacological prevention and treatment management policies; and miscellanous.

Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)

Articles 110 Documents

1 2 3 4 5

Comparison of Anxiety Level on Medical Skill Examination Between Students of Medical Faculty of Hang Tuah University Surabaya in 1st Semester Who Have Received Mental Health Tests During The Entrance Test with 3rd Semester Who Have Not Martua, Edwin Timotius; Wendra, Sadya; Simon, Edward Imanuel
Oceana Biomedicina Journal Vol 2, No 1 (2019): Oceana Biomedicina Journal
Publisher : Universitas Hang Tuah

Anxiety is an unpleasant feeling of insecure tension and fear that arises because it feels something will happen that is disappointing but the source is largely unaware by the person concerned. Various studies have shown a high frequency of anxiety symptoms in medical students.The aim of this study is knowing the comparison of the level of anxiety to the medical skills test between students of Medical Faculty of Hang Tuah University Surabaya in 1ST semester who have received mental health tests during the entrance test with 3RD semester who have not received a mental health test during the entrance test.This study was an observational analytic study with a cross-sectional study design. The sampling technique used in this study is stratified random sampling. The population in this study were the first and third semester students of the Medical Faculty of Hang Tuah University Surabaya in the 2017/2018 school year, while the samples taken were 374 students meeting the inclusion criteria, Assessment of anxiety levels was carried out using the Hamilton Rate Scale for Anxiety (HRSA) questionnaire.Mild anxiety levels are more numerous in first-semester students (75%) compared to third-semester students (50%), while moderate-to-severe anxiety levels are more numerous in third-semester students (40%) compared to first-semester students (12.5%) who have received mental health tests during the entrance test.This study concluded there is a difference of ansiety level on medical skill examination between students of medical faculty of Hang Tuah University Surabaya in 1st semester who have received mental health tests during the entrance test with 3rd semester who have not received a mental health test during the entrance test. Keywords: Anxiety level, medical skills test, mental health test

The infection of Vibrio parahaemolyticus in shrimp and human Praja, Rian Ka
Oceana Biomedicina Journal Vol 1, No 1 (2018): Oceana Biomedicina Journal
Publisher : Universitas Hang Tuah

Vibrio parahaemolyticus is an aquatic zoonotic agent that can threaten human and aquaculture animal health. Humans can be infected by consuming contaminated raw seafood or wound-related infections. Generally infection of V. parahemolyticus is orally transmitted and causes gastroenteritis in humans while in aquaculture animals especially shrimp can cause Acute Hepatopancreatic Necrosis Disease (AHPND) or Early Mortality Syndrome (EMS) with a very high mortality rate and cause economic losses. Shrimp species susceptible to infection are Litopenaeus vannamei, Penaeus monodon, and P. chinensis. V. parahaemolyticus produces several toxins in human disease such as thermostable direct hemolysin (TDH), TDH-related haemolysin (TRH), and thermolabile hemolysin (TLH). Meanwhile, Photorabdus insect-related (Pir) toxins consisting of PirAvp and PirBvp are the toxins associated with AHPND in shrimp. The genes that encode the toxin are used as targets to diagnose V. parahaemolyticus pathogens molecularly. Until now the treatment of V. parahaemolyticus infection is using antibiotics and fluid therapy, but there were V. parahaemolyticus isolates from aquaculture that have been resistant to antibiotics so that the use of antibiotics in aquaculture must be controlled and the use of alternative therapy are very important to be developed to control V. parahaemolyticus infection. Keywords: V. parahaemolyticus, zoonotic, gastroenteritis, Acute Hepatopancreatic Necrosis Disease (AHPND), Early Mortality Syndrome (EMS).

Cervix Carcinoma: Pathological Aspect Nefertiti, Eva Pravitasari
Oceana Biomedicina Journal Vol 1, No 2 (2018): Oceana Biomedicina Journal
Publisher : Universitas Hang Tuah

Cervix carcinoma is a malignancy at squamocollumnar junction, in the border between ecto and endo cervix. Lesion at this site is frequently correlated with chronic inflammatory of the cervix, displacia, and in situ carcinoma. InIndonesia, cervix carcinoma is the most common malignancy in women. At Obstetry and Gynecology Department of RSCM during 1986-1990 period, 2360 gynocology carcinoma were found, and 1821 (77,2%) cases of them were cervix carcinoma. The diagnosis was made based on cytology, colposcopy, biopsy, endocervix curettage and conitation. Papanicolaou test is a useful in detecting early stage of cervix carcinoma up to 90% accuration. The speciment for paps smear is secrets of the vagina, cervix, endocervix, endometrium, and posterior fornix.key words : cervix carcinoma, cytology, papsmear

The Difference of Positive or Negative Views on Patients of Soul Disorders Between Students of Faculty of Medicine Hang Tuah University Surabaya Semester 5 with Semester 7 Pangestika, Fifin Yulia Candra; Wendra, Sadya; Simon, Edward Imanuel
Oceana Biomedicina Journal Vol 2, No 1 (2019): Oceana Biomedicina Journal
Publisher : Universitas Hang Tuah

Background: Most people in Indonesia still negatively regard mental patients as someone who is dangerous and the disease cannot be cured. This happens because people do not understand well the causes and methods of care for patients with mental disorders. Negative views that exist in the community cause mental patients to get less appropriate and humane treatment in the community even in their own families, such as being installed, ignored, insulted, and alienating family members who experience mental disorders.Objectif: This study aims to determine the differences in positive or negative views of mental patients between students of the Faculty of Medicine, Hang Tuah Surabaya, 5th semester with 7th semester.Methods: The population in this study were students of the Faculty of Medicine, University of Hang Tuah Surabaya in semester 5 with semester 7. with a large sample taken as many as 136 people. The independent variables in this study were positive or negative views about mental patients while the dependent variables in this study were students of semester 5 and semester 7 students. Analysis of the data of this study using Chi Square statistical tests.Results: Obtained results of respondents from semester 5 with a positive outlook that is 38 people (55.9%) and negative views namely 30 people (44.1%), then the results of respondents from 7th semester with a positive outlook that is 53 people (77.9%) and negative view of 15 people (22.1%). Where the total number of all respondents who answered a positive view was 91 people (66.9%) and all respondents who answered negative views were 45 people (33.1%). And based on gender, male respondents who looked positively about mental patients were 51 people (66.2%) and those who viewed negativity were 26 people (33.8%). Whereas female respondents who viewed positively regarding mental patients were 40 people (67.8%) and those who viewed negatively were 19 people (32.2%).Conclusions: The results showed a significant difference regarding the differences in positive or negative views of mental patients between semester 5 students and 7th semester students, as evidenced by the acquisition of the Sig. = 0.006 (<0.05).Keywords: Differences in Positive or Negative Views, Mental Disorders

Ethanolic Extract of The Graptophyllum Pictum Griff Leaves as Antipyretic agent to Male White Rat Rikomah, Setya Enti; Lestari, Gina; Winanti, Juwita
Oceana Biomedicina Journal Vol 1, No 1 (2018): Oceana Biomedicina Journal
Publisher : Universitas Hang Tuah

Utilization of plants as traditional medicinal are still always be used by people in Indonesian. Especially in rural areas that still rich with variety of plants. Plants of black pudding leaves (Graptophyllum pictum Griff) are one that efficacious for treating various of diseases. The content of flavonoid in the black pudding leaves have antipyretic effect, analgesic and anti-inflammatory. This research aims to find out whether the black pudding leaves have antipyretic effect or not. This research used the induction method of vaccineDPT-Hb 0.022 / 20 gr a white rat as stimulant fever. Positive control with paracetamol 1.3 mg / 20 gram a white rat, negative control with Na CMC 0.5 ml / 20 grams a white rat, first extract test of black pudding leaves 0.8 mg / 20 gram a white rat, second extract test of black pudding leaves 1.6 / 20 gram a white rat, and third extract test of black pudding leaves 3.2 / 20 gram a white rat. The results of research showed that ethanol extract of black pudding leaves if it’s looked from statistic result of SPSS 16 program , it doesn’t show out of any effect as antipyretic effect because the significant value is P> 0.05.Keywords: Antipyretic, DPT vaccine Hb, (Graptophyllum pictum)

Molecular Mechanism of Cholerae Toxin (ctx) in Causing Diarrhea Praja, Rian Kusuma Arinta; Rosalina, Reny
Oceana Biomedicina Journal Vol 1, No 2 (2018): Oceana Biomedicina Journal
Publisher : Universitas Hang Tuah

Vibrio cholerae is one of the pathogenic bacteria transmitted through contaminated food, especially seafood and contaminated beverages. V. cholerae produces cholerae toxin (ctx) which is encoded by the ctx gene located within its chromosome. This toxin has been recognized as one of the toxins responsible for cholera outbreaks. The mechanism of ctx gene expression is induced by environmental signals such as pH, osmolarity, temperature, bile, amino acids, and CO2. These signals will be a positive transcriptional factor to the ToxR gene that regulates the biogenesis of cholerae toxin. After cholerae toxin has been successfully expressed, V. cholerae uses a type II secretion (T2S) pathway to deliver cholerae toxin to the extracellular environment. Cholerae toxin consists of A and B subunits. The B subunit plays a role in attaching to the receptor Manosialosyl Ganglioside (GM1 ganglioside) and the A subunit plays a role in catalyzing ADP-ribosylation of Gs (stimulatory) proteins and turning them into active condition. The Gs proteins will convert the inactive adenilate cyclase (AC) into active AC. The increase of AC activity will increase the cyclic adenosine 3'5'-monophosphate (cAMP) concentration along the cell membrane. The cAMP then causes the active secretion of sodium (Na+), chloride (Cl-), potassium (K+), bicarbonate (HCO3-), and water (H2O) out of the cell into the intestinal lumen, resulting in large fluid losses and electrolyte imbalances. Keywords: Vibrio cholerae, cholerae toxin (ctx), ToxR gene, type II secretion (T2S), GM1 ganglioside, adenilate cyclase.

Recent Therapeutics Policies of Arthritis Rheumatoid (part I) Andisari, Hendrata Erry
Oceana Biomedicina Journal Vol 1, No 1 (2018): Oceana Biomedicina Journal
Publisher : Universitas Hang Tuah

Therapy in RA has undergone many advances today and in line with knowledge of the pathogenesis of RA, the current therapeutic goal is to alter the journey and control the activity of RA disease. Several groups of drugs have been used in RA therapy including non-steroidal anti-inflammatory drugs (NSAIDs), conventional disease-modifying antirheumatic drugs (DMARDs) as well as biological agents (bDMARD), glucocorticoids and anti-pain medicines. In recent years, the development of biological agents that have specific targets for inflammatory mediators such as interleukin (IL) -1, IL-6 and Tumor Necrosis Factor (TNF) suggests a potent therapeutic effect on RA. In this article will be presented the latest biological agents as the latest therapy on RA.

Manalagi Apple Vinegar (Malus sylvestris Mill) as Anti Diabetic to Alloxan Induced Wistar White Male Rat Purnomo, Valentina Verrel; Tjandra, Agustinus Sareh Arjono; Risma, Risma
Oceana Biomedicina Journal Vol 2, No 1 (2019): Oceana Biomedicina Journal
Publisher : Universitas Hang Tuah

Apple vinegar is estimated to be able to cure diabetes. Vinegar is able to control the increase of glicemic index. Apple has antioxidant substance such as quercetin and chlorogenic acid. Manalagi apple could be found easily in Indonesia. This research aims to reveal the effect of Manalagi apple vinegar (Malus sylvestris Mill) towards blood glucose level of alloxan induced Wistar white male rats (Rattus norvegicus). This research is experimental laboratory using Experimental methods. The samples are 30 white rats divided into three groups for 31 days, 1) group which only given standard diet; 2) group that induced by 120mg/dL alloxan; 3) group that induced by 120mg/dL alloxan and Manalagi apple vinegar 0.27ml/100gram weight for 14 days. The measurement of blood serum glucose level is done on day twenty four using homogenous colorimetric enzymatic test method for all groups. Blood glucose average in group with only given standard diet as negative control group (182.33 mg/dL), group which induced by 120mg/dL alloxan as positive control group (205.2 mg/dL), group which induced by 120mg/dL alloxan and Manalagi apple vinegar as treatment group (212.25 mg/dL). The result of One-Way Anova significance is 0.229. The conclusion of this research is that Manalagi apple vinegar treatment doesn’t able to decrease the blood glucose level of white Wistar male rats significantly. Keywords : Malus sylvestris Mill, Blood glucose, Alloxan.

Empirical Antibiotic Therapy Assessment of Patients diagnosed with Sepsis in Intermediate Care Ward of Internal Medicine Department of Dr. Soetomo General Hospital according to Gyssens Method Adiwinoto, Ronald Pratama; Sustini, Florentina; Hardiono, Hardiono; Widodo, Agung Dwi Wahyu; Hidajat, Boerhan; Hadi, Usman
Oceana Biomedicina Journal Vol 1, No 2 (2018): Oceana Biomedicina Journal
Publisher : Universitas Hang Tuah

Rational empirical antimicrobial therapy is an important component of sepsis patient management. This study aimed to assess the rationality of empirical antimicrobial therapy in patients diagnosed with sepsis admitted in intermediate care ward of internal medicine department (RPI) of Dr. Soetomo General Hospital from January 2016 to July 2017. Medical records of 91 patients diagnosed with sepsis were collected and studied retrospectively in period from July 2017 to November 2017. 91 (85.05%) medical records from 107 sepsis patients were evaluated. Cultures and antimicrobial sensitivity tests were carried out in 21 (23.07%) patients. 14 patients yielded positive culture results, 9 of which were MDRO positive with ESBL as resistant marker. Empirical antibiotic therapies for these patients were reviewed according to Gyssens method.73 (80.2%) of 91 patients were deemed receiving appropriate empirical antibiotic therapies. Ceftriaxone IV injection as monotherapy or combination therapy were the most common empirical antibiotic therapies (82 in 91 patients, 90.1%), despite local microbiologic flora and antibiogram show most pathogens were resistant to ceftriaxone. Mortality rate in this study was high, 92.3% (84 patients died) despite rational empirical antibiotic therapies were high. This study concluded that empirical antibiotic therapies in sepsis patients according to guidelines adopted in Soetomo General Hospital, albeit deemed rational, was no longer appropriate according to local antibiogram issued by microbiological department of Soetomo General Hospital. Keywords: Empirical Antibiotics Therapy, Gyssens criteria, Intermediate Care Ward, Sepsis, Septic Shock

Detection of genes encoding ompW and ctxA of Vibrio cholerae isolated from shrimp and shellfish at Kedonganan fish market, Bali-Indonesia Kusuma Praja, Rian Arinta; Sukrama, I Dewa Made; Fatmawati, Ni Nengah Dwi
Oceana Biomedicina Journal Vol 2, No 1 (2019): Oceana Biomedicina Journal
Publisher : Universitas Hang Tuah

Contamination of pathogenic bacteria in food can lead to the emergence of foodborne disease. One of foodborne disease which often occurs in some developing countries such as Africa, Southeast Asia, and Latin America is cholera which is caused by Vibrio cholerae. The disease is transmitted through beverages and food, especially contaminated seafood. V. cholerae has several virulence factors including the outer membrane protein W (ompW) and cholerae toxin (ctx).The ompW acts as a protective barrier and can also be used as a marker specific species of V. cholerae and cholerae toxin is an enterotoxin responsible for the incidence of diarrhea in a cholera outbreak produced by pathogenic V. cholerae. This study was an observational study to determine the level of contamination of V. cholerae by detecting the outer membrane protein W (ompW) and cholerae toxin subunit A (ctxA) gene of V. cholerae in shrimp and shellfish sold at Kedonganan fish market. Samples were taken using total sampling technique and obtained 24 samples consisting of 14 shrimp samples and 10 shellfish samples. Samples were examined using culture methods and biochemical tests, and then further tested using Duplex Polymerase Chain Reaction (dPCR) to detect ompW and ctxA gene. The dPCR assay results showed 8 out of 14 (57.1%) samples from shrimp and 1 out of 10 (10%) samples from the shellfish positive carried ompW gene, and found no positive samples carrying the ctxA gene in samples derived from shrimp and shellfish. Chi square test analysis results indicated contamination of V. cholerae in shrimp was higher than shellfish based on ompW gene (p<0.05). It can be concluded that the shrimp and shellfish at Kedonganan fish market are contaminated by V. cholerae. Further research is needed to detect the virulence factors besides ompW and ctxA of V. cholerae in seafood. Keywords: Foodborne disease, Vibrio cholerae, ompW gene, ctxA gene, and Duplex Polymerase Chain Reaction (dPCR).

Page 1 of 11 | Total Record : 110

1 2 3 4 5

Filter by Year

2018 2024

Filter By Issues

All Issue Vol 7 No 1 (2024): Oceana Biomedicina Journal Vol 6 No 2 (2023): Oceana Biomedicina Journal Vol 6 No 1 (2023) Vol 5 No 1 (2022): Oceana Biomedicina Journal Volume 5 Issue (No) 1 Vol 5 No 2 (2022): Oceana Biomedicina Journal Vol 4 No 1 (2021): Oceana Biomedicina Journal Volume 4 Issue (No) 1 January - June 2021 Vol 4 No 2 (2021): Oceana Biomedicina Journal Volume 4 Issue (No) 2 Vol 3 No 2 (2020): Oceana Biomedicina Journal Volume 3 Issue (No) 2 July - December 2020 Vol 3 No 1 (2020): Oceana Biomedicina Journal Volume 3 Issue (No) 1 January - June 2020 Vol 3, No 1 (2020): Oceana Biomedicina Journal Vol 2 No 2 (2019): Oceana Biomedicina Journal Volume 2 Issue (No) 2 July - December 2019 Vol 2 No 1 (2019): Oceana Biomedicina Journal Volume 2 Issue (No) 1 January - June 2019 Vol 2, No 2 (2019): Oceana Biomedicina Journal Vol 2, No 1 (2019): Oceana Biomedicina Journal Vol 1 No 2 (2018): Oceana Biomedicina Journal Volume 1 Issue (No) 2 July - December 2018 Vol 1 No 1 (2018): Oceana Biomedicina Journal Vol 1 Issue (No) 1 January-June 2018 Vol 1, No 2 (2018): Oceana Biomedicina Journal Vol 1, No 1 (2018): Oceana Biomedicina Journal More Issue

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name
Erina Yatmasari

Contact Email
erina.yatmasari@hangtuah.ac.id

Phone
+628121752228

Journal Mail Official
biomedicina@hangtuah.ac.id

Editorial Address
Jl. Gadung 1 Kompleks Barat RSPAL dr. Ramelan Surabaya, Indonesia

Location
Kota surabaya,

Jawa timur

INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Erina Yatmasari

Contact Email erina.yatmasari@hangtuah.ac.id

Phone +628121752228

Journal Mail Official biomedicina@hangtuah.ac.id

Editorial Address Jl. Gadung 1 Kompleks Barat RSPAL dr. Ramelan Surabaya, Indonesia

Location Kota surabaya, Jawa timur INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Erina Yatmasari

Contact Email
erina.yatmasari@hangtuah.ac.id

Phone
+628121752228

Journal Mail Official
biomedicina@hangtuah.ac.id

Editorial Address
Jl. Gadung 1 Kompleks Barat RSPAL dr. Ramelan Surabaya, Indonesia

Location
Kota surabaya,

Jawa timur

INDONESIA