JFIOnline
Vol 9, No 1 (2017): Punica Granatum

Aktivitas Anti inflamasi Ekstrak Etanol Uwi Banggai Ungu (DioscoreaAlataL.) Terhadap Tikus Putih Galur Wistar Yang Induksi Putih Telur

Khaerati, Khildah (Unknown)
Rivani, Rivani (Unknown)
Ihwan, Ihwan (Unknown)



Article Info

Publish Date
11 Mar 2019

Abstract

ABSTRACT: Purple uwi Banggai (Dioscorea alata L.) is a plant used as a source of carbohydrates and also has many benefits. This research aimed is to know the dosage of ethanol extract of purple uwi Banggai which is effective as anti-inflammatory to white rat (Rattus norvegicus). This research used 25 test animals that were divided into five groups. All groups were induced with 100% egg whites with subplantar method, after 60 minutes each group was given different suspension. The negative control group was given a 0.5% Na CMC suspension, meanwhile positive control group was given 9 mg / 200 gBB mefenamic acid, and the third, fourth, and fifth groups were given test suspension with variation of doseĀ  200, 250, 300 mg / 200 gBB, then measured again inflammation volume with pletismometer for 6 hours with 60 minutes interval. Data were analyzed statistically using ANOVA. The result showed that the ethanol extract of purple uwi Banggai have anti-inflammatory effect on white rat induced egg white 100%. The effective dose as antiinflammatory is 200 mg / 200gBB.

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Journal Info

Abbrev

jurnal

Publisher

Subject

Health Professions Medicine & Pharmacology

Description

Jurnal Farmasi Indonesia yang diterbitkan oleh Pengurus Pusat Ikatan Apoteker Indonesia. Isi website memuat seluruh jurnal yang telah diterbitkan mencakup semua aspek dalam ilmu pengetahuan dan teknologi kefarmasian antara lain farmakologi, farmakognosi, fitokimia,farmasetika, kimia farmasi, biologi ...