A New Triterpene Glycoside from the Sea Cucumber Holothuria Scabra Collected in Vietnam

Nguyen Van Thanh (Institute of Natural Products Chemistry, Vietnamese Academy of Science and Technology, 18 Hoang Quoc Viet, Caugiay, Hanoi)
Nguyen Hai Dang (Institute of Natural Products Chemistry, Vietnamese Academy of Science and Technology, 18 Hoang Quoc Viet, Caugiay, Hanoi)
Phan Van Kiem (Institute of Natural Products Chemistry, Vietnamese Academy of Science and Technology, 18 Hoang Quoc Viet, Caugiay, Hanoi)
Nguyen Xuan Cuong (Institute of Natural Products Chemistry, Vietnamese Academy of Science and Technology, 18 Hoang Quoc Viet, Caugiay, Hanoi)
Hoang Thanh Huong (Institute of Natural Products Chemistry, Vietnamese Academy of Science and Technology, 18 Hoang Quoc Viet, Caugiay, Hanoi)
Chau Van Minh (Institute of Natural Products Chemistry, Vietnamese Academy of Science and Technology, 18 Hoang Quoc Viet, Caugiay, Hanoi)

ASEAN Journal on Science and Technology for Development
Vol. 23 No. 4 (2006): ASEAN Journal on Science and Technology for Development (AJSTD)

Bioassay guided fractionation led to the isolation of a new triterpene glycoside, holothurinogenin B (1) along with three known compounds, holothurin B (2), holothurin A (3), and holothurin A2 (4), from the methanol extract of the Vietnamese sea cucumber Holothuria scabra. Their structures were deduced from the spectral analysis (1D-NMR, 2D-NMR, MS) and chemical evidences.