ASEAN Journal on Science and Technology for Development
Vol. 25 No. 2 (2008): ASEAN Journal on Science and Technology for Development (AJSTD)

APPLICATION OF NMR IN THE INVESTIGATION OF DYNAMIC TAUTOMERISM OF 4(3H)-QUINAZOLINONE SYSTEM

Pham Thi Thanh My (Institute of Chemistry, Vietnamese Academy of Science and Technology)
Chu Dinh Kinh (Institute of Chemistry, Vietnamese Academy of Science and Technology)
Thanh Thi Thu Thuy (,Institute of Chemistry, Vietnamese Academy of Science and Technology)
Nguyen Ngoc Vinh (Institute of Drug Quality Control, Ho Chi Minh City)
Nguyen Thi Phuong Chi (Vietnamese Academy of Science and Technology)

Article Info

Publish Date
22 Nov 2017

Abstract

Tautomerism of 4(3H)-quinazolinone system with [(2-hydroxyphenyl)methylene]-2-(4oxoquinazolin-3(4H)-yl)acetohydrazide and N’-[(1E)-(4-hydroxy-3-methoxyphenyl)methylene]-2-(4-oxoquinazolin-3(4H)-yl)acetohydrazide as two representative compounds was investigated on the basis of 1H NMR method at coalescence with the help of line formprogramme. The dynamic parameters such as k, Ea, DG*, DH*, DS* were fully calculated with high reliability.

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Journal Info
ASEAN Journal on Science and Technology for Development
Website

Abbrev

ajstd

Publisher

Universitas Gadjah Mada

Subject

Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Mathematics

Description

The coverage is focused on, but not limited to, the main areas of activity of ASEAN COST, namely: Biotechnology, Non-Conventional Energy Research, Materials Science and Technology, Marine Sciences, Meteorology and Geophysics, Food Science and Technology, Microelectronics and Information Technology, ...