Jurnal Ilmu Kefarmasian Indonesia
Vol 10 No 1 (2012): JIFI

Sintesis Analog 3-0-Benzylstentorin sebagai Prekursor untuk Kerangka Dasar Blepharismin

TENI ERNAWATI (LEMBAGA ILMU PENGETAHUAN INDONESIA)
YOSHINOSUKE USUKI (FACULTY OF SCIENCE OSAKA CITY UNIVERSITY)
HIDEO IIO (FACULTY OF SCIENCE OSAKA CITY UNIVERSITY)

Article Info

Publish Date
30 Apr 2012

Abstract

A Method for the synthesis of precursor for the basic skeleton of blepharismin and structural analog was described. Such compound is identified as potential drug for the treatment of antiviral and photodynamic therapy. Benzyl stentorin analog as the basic skeleton of blepharismin was effectively synthesized via reaction one of hydroxyl groups in bianthraquinone derivative with p-methoxybenzylchloride in the presence of potassium carbonate as base. Dimerization of bromo anthraquinone derivative produced dimmer in 55% while the formation of compounds analogous of 3-0-benzylstentorin resulted in 70% yield.

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Journal Info
Jurnal Ilmu Kefarmasian Indonesia
Website

Abbrev

jifi

Publisher

Universitas Pancasila

Subject

Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Public Health

Description

Jurnal Ilmu Kefarmasian Indonesia (JIFI) mainly focuses on a current topic in Pharmaceutical Sciences are also considered for publication by the Journal. Discussions on a topic in Pharmaceutical Sciences, Clinical Sciences, and Social Behaviour Administration. Detailed scopes of articles accepted ...