Jurnal Ilmu Kefarmasian Indonesia
Vol 15 No 2 (2017): JIFI

Analisis Kualitatif Uji Strip Sildenafi l Sitrat dengan Kombinasi Beberapa Reagen dalam Membran Kertas Selulosa

Yessy Gladiani Sutrisno (UNIVERSITAS JENDRAL SOEDIRMAN)
Siska Khoirunnisa (UNIVERSITAS JENDRAL SOEDIRMAN)
Diani Sri Agustien (UNIVERSITAS JENDRAL SOEDIRMAN)
Eva Karyati (UNIVERSITAS JENDRAL SOEDIRMAN)
Nabila Fasya (UNIVERSITAS JENDRAL SOEDIRMAN)
Hendri Wasito (UNIVERSITAS JENDRAL SOEDIRMAN)



Article Info

Publish Date
30 Sep 2017

Abstract

Sildenafi l citrate was widely used to treat erectile dysfunction in men. The high demand of this drug, infl uence of counterfeit drugs. Therefore, it is required an analytical method to determine the authenticity of this drug. The aims of this research were to develop and evaluate of strip test for sildenafi l sitrat identifi cation. Research was conducted by preparation of solution and choosing the appropriate reagent for sildenafi l citrate. The optimum reagents were immobilized in cellulose paper followed by manufactured into strip test. Product performance was evaluated by evaluating several test in termed of qualitative, reproducibility, specifi city and response time. The results showed that the optimum membrane product was consisted of copper sulfate and sodium bicarbonate (2:1); ammonium ferric sulfate hexahydrate and copper acetat (1:3); sodium sulfate, copper acetate and ammonium ferrite sulfate (2:1:1) and mercury acetate and copper sulfate (2:1) reagents. The strip test had a capability in specifi c identify of sildenafi l citrate with a good reproducibility and less than ten seconds for time response. The strip test developed could be used as an early detection tool for the authenticity of a sildenafi l citrate tablet which more rapid.

Copyrights © 2017






Journal Info

Abbrev

jifi

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Public Health

Description

Jurnal Ilmu Kefarmasian Indonesia (JIFI) mainly focuses on a current topic in Pharmaceutical Sciences are also considered for publication by the Journal. Discussions on a topic in Pharmaceutical Sciences, Clinical Sciences, and Social Behaviour Administration. Detailed scopes of articles accepted ...