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Nabila Fasya
UNIVERSITAS JENDRAL SOEDIRMAN
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Public Health

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Analisis Kualitatif Uji Strip Sildenafi l Sitrat dengan Kombinasi Beberapa Reagen dalam Membran Kertas Selulosa Yessy Gladiani Sutrisno; Siska Khoirunnisa; Diani Sri Agustien; Eva Karyati; Nabila Fasya; Hendri Wasito
JURNAL ILMU KEFARMASIAN INDONESIA Vol 15 No 2 (2017): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (449.398 KB) | DOI: 10.35814/jifi.v15i2.502

Abstract

Sildenafi l citrate was widely used to treat erectile dysfunction in men. The high demand of this drug, infl uence of counterfeit drugs. Therefore, it is required an analytical method to determine the authenticity of this drug. The aims of this research were to develop and evaluate of strip test for sildenafi l sitrat identifi cation. Research was conducted by preparation of solution and choosing the appropriate reagent for sildenafi l citrate. The optimum reagents were immobilized in cellulose paper followed by manufactured into strip test. Product performance was evaluated by evaluating several test in termed of qualitative, reproducibility, specifi city and response time. The results showed that the optimum membrane product was consisted of copper sulfate and sodium bicarbonate (2:1); ammonium ferric sulfate hexahydrate and copper acetat (1:3); sodium sulfate, copper acetate and ammonium ferrite sulfate (2:1:1) and mercury acetate and copper sulfate (2:1) reagents. The strip test had a capability in specifi c identify of sildenafi l citrate with a good reproducibility and less than ten seconds for time response. The strip test developed could be used as an early detection tool for the authenticity of a sildenafi l citrate tablet which more rapid.
Pengembangan Formulasi Pasta Antiinflamasi Piroksikam Berbasis Ampas Tahu dalam Pemanfaatan Limbah Tahu Di Purwokerto Nita Triana Sari; Putri Dewi Riayah; Nabila Fasya; Ainul Mardziyati A; Namira Fadhilah B; Nuryanti Nuryanti
JURNAL ILMU KEFARMASIAN INDONESIA Vol 15 No 2 (2017): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (919.432 KB) | DOI: 10.35814/jifi.v15i2.505

Abstract

The soybean curd residue is the waste product of soybean. It has potential for being excipients in pharmaceutical preparations because of its high carbohydrate element. This study aims to evaluate the soybean curd residue as excipients of piroxicam antiinfl ammatory paste. The excipient of soybean curd residue is made by isolating it with 0.1% KOH, then being characterized by physical, chemical, and functional test after becoming starch. It was prepared in piroxicam antiinfl ammatory paste preparations with ratio of soybean curd residue starch and manihot strach are F1 (0:0.25), F2 (0.25:0), F3 (1.25:1.25), F4 (1.5:1), and F5 (1:1.5). The result of physical and freeze-thaw stability test were analyzed descriptively. The data of viscosity, stickiness, and spreading power test were analyzed using one-way ANOVA. Soybean curd residue starch’s physic is slightly coarse, cubic-shapes powder, uneven surface and nonporous, slightly hygroscopic, and brownish-white. It has distinctive odor and has no taste. Chemical test showed that it contained carbohydrate and had pH 4.9. Functional test showed on average 15% it has viscosity 1959 cps, fl ow time 6.7 seconds and still angle 39.2o. Results of physical and stability tests showed that F3 were the best piroxicam antiinfl ammatory paste formula.
Co-Authors Ainul Mardziyati A Diani Sri Agustien Eva Karyati Hendri Wasito Namira Fadhilah B Nita Triana Sari Nuryanti Nuryanti Putri Dewi Riayah Siska Khoirunnisa Yessy Gladiani Sutrisno