Aktifitas Stimulan Sistem Saraf Pusat Ekstrak Biji Pinang ( Areca catechu, L ) Terhadap Mencit Putih ( Mus musculus, L)

Suhatri Suhatri (Fakultas Farmasi Universitas Andalas Padang)
Yimmi Syavardie (Sekolah Tinggi Ilmu Farmasi (STIFARM) Padang)
Zet Rizal (Sekolah Tinggi Ilmu Farmasi (STIFARM) Padang)

Jurnal Farmasi Higea
Vol 3, No 1 (2011)

The stimulant activity of central nerve systems of areca seed (Areca cathecu, L.), at white mouse ( Mus musculus, L ) had been done by using method hanging test, evasi test, swim test and discrimination maze. Drug dose given is 0.5 mg/20 gram BW white mouse, 1 mg/20 gram BW white mouse, 2 mg/ 20 gram BW white mouse in oral mechanism. As negative control is applied by Tween 80 2% and condensation of comparator is applied by Caffeine.Activity test result from seed extract Pinang ( Areca cathecu, L. ) to white mouse ( Mus musculus, L. ) the obtained result signifikan ( P < 0.01 ) as stimulant central nerve systems.