Jurnal Farmasi Higea
Vol 4, No 2 (2012)

Pembuatan Natrium Karboksimetil Selulosa (Na CMC) Dari Batang Rumput Gajah (Pennisetum purpureum Schumach)

Zulharmitta Zulharmitta (Fakultas Farmasi Universitas Andalas Padang)
Silvia Maryani (Sekolah Tinggi Ilmu Farmasi (STIFARM) Padang)
Roslinda Rasyid (Fakultas Farmasi Universitas Andalas Padang)



Article Info

Publish Date
26 Jan 2017

Abstract

A study on the preparation of sodium carboxymethil cellulose (Na-CMC) from celulose powder that was isolated from the stems elephant grass (Pennisetum purpureum Schumach) has been performed. Cellulose was purified using 17.5% of sodium hydroxide solution, then bleach, dried and crushed to obtain alpha cellulose. Alfa cellulose was eterified with sodium chloroacetat resulting sodium carboxymethyl cellulose, furthermore characterized: organoleptic, losses on drying, chemical identification, pH test and test with fourier transform infrared (FT-IR). The results showed that of 300 g stems elephant grass yield alpha cellulose as much as 92,.54 g and 25 g of alpha cellulose produced  Na-CMC as 16.92 g. Based on the characterization made Na-CMC and Na-CMC Merck®  meet Indonesian Pharmacopoeia 3th edition requirement.

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