Jurnal Farmasi Higea
Vol 9, No 1 (2017)

Formulasi Dan Evaluasi Stabilitas Fisik Suspensi Ibuprofen Menggunakan Kombinasi Polimer Serbuk Gom Arab Dan Natrium Karboksimetilselulosa

Rina Wahyuni (Sekolah Tinggi Ilmu Farmasi (STIFARM) Padang)
Syofyan Syofyan (Fakultas Farmasi Universitas Andalas (UNAND) Padang)
Septa Yunalti (Sekolah Tinggi Ilmu Farmasi (STIFARM) Padang)



Article Info

Publish Date
15 Apr 2017

Abstract

The research about formulation and evaluation of physical stability of ibuprofen suspension using arabic gom and  natrium carboxymethylcelulose as suspending agent had been done. Concentration of arabic gom and  natrium carboxymethylcelulose were 2.5 : 0.25, 5 : 0.5, 2.5 : 0.75 and 5 : 1 % for F1, F2, F3 and F4 respectinely. Evaluation of physical stability had been done  for 8 weeks, ie organoleptic, density, viscosity, volume of sedimentation, redispresion, pH, freeze thaw cycling, crystal growth and particle size distribution. Concentration of arabic gom and natrium carboxymethylcelulose had been influenced the physical stability of suspension.

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