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Journal of Medical Biomedical and Applied Sciences

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Published by Innovative Journal

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Core Subject : Health, Science,

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

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Articles 5 Documents

Search results for , issue " Vol 6 No 3 (2018)" : 5 Documents clear

Comparative Dynamics of The Efficiency of Antithrombotic Prophylaxis Before Delivery In Pregnant Women With Different Forms of Antiphospholipid Synrome Gurbanova, J.F.; Guliyeva, M.A.
Journal of Medical Biomedical and Applied Sciences Vol 6 No 3 (2018)
Publisher : Journal of Medical Biomedical and Applied Sciences

Objectives: The aim of this study was the assessment of effectiveness of antithrombotic prophylaxis in pregnant women with different form of APS. Methods of study: For the assesment of condition and effectiveness of treatment of pregnants, the investigations were carried out in 92 women. In various periods of pregnancy were determined non-active thrombin-antithrombin III (TAT) complex, protrombin fragments (F1+2), D-dimer et c. Results and conclusions: Long-term antithrombotic prophylaxis with low-molecular heparins allows to decrease the level of thrombophilic markers in pregnant women with different forms of APS. Monotherapy with low-molecular heparins in women allows to normalize the level of thrombofilic markers and effectively prevents thrombosis.

âA POTENTIAL NONINVASIVE BIOMARKER OF NONALCOHOLIC STEATOHEPATITISâ Oliveira, Yanaihara Pinchemel; Cotrim, Helma; Daltro, Carla; Alves, Erivaldo; Barros, Raffaelle
Journal of Medical Biomedical and Applied Sciences Vol 6 No 3 (2018)
Publisher : Journal of Medical Biomedical and Applied Sciences

Background/Aim: Liver biopsy remains the gold standard for characterizing the histology of nonalcoholic fatty liver disease, yet this procedure is invasive. Oxidative stress plays an important role in the pathogenesis of steatohepatitis and erythrocytesare known to exert pro-oxidant activity. We hypothesized that erythrocytes damaged by oxidative stress could represent potential biomarkers capable of distinguishing steatosis from steatohepatitis. Methods: Our sample included 37 obese patients who underwent bariatric surgery and liver biopsy. Patients were classified according to histological diagnosis with respect to steatosis or steatohepatitis. Oxidative stress measurements were performed by chemiluminescence. Erythrocytes obtained from the whole blood of patients were stained to evaluate cell morphology by optical microscopy. Results: Higher levels of oxidative stress were seen in obese patients with steatohepatitis in comparison to those with steatosis (Cohens d=4.1). Erythrocytes damaged by oxidative stress were found in 81.2% of patients with steatosis and in 95.2% of the steatohepatitis cases (Phi= 0.22). These results were confirmed in an in vitro model. Oxidative stress levels were found to be elevatedin 60.6% of the cases in which modified erythrocytes were also present. Conclusions: The results indicated that altered erythrocytes may represent a novel noninvasive biomarker capable of distinguishing steatosis from steatohepatitis.

Renal Perinephric Abscess Complicated with Psoas Muscle Abscess D, Kochiashvili; T, Didbarize; V, Kvakhajelidze; G, Kochiashvili
Journal of Medical Biomedical and Applied Sciences Vol 6 No 3 (2018)
Publisher : Journal of Medical Biomedical and Applied Sciences

Perinephric abscess is an uncommon complication of urinary tract infections. The incidence ranges from 1-10 cases for every 10000 hospital admissions. Men and women are affected with equal frequency. Escherichia coli, Proteus speacies and Staphylococcus aureus are the unusual etiologic organisms. There were very few reports about urinary tract infections such as renal perinephric abscess complicated with psoas muscle abscess.Renal and perirenal abscess can complicate aurologic infection (usually due to gram-negative enteric bacilli or a polymicrobial infection). This clinical case of a 24 year old men with predisposing condition for secondary psoas muscle abscess (6 year history of the right non functional kidney), is interesting because of unusual etiologic organisms for psoas muscle abscess Proteus mirabilis, which is highly flagellate, have stone formation ability which is very difficult to clear with only antibiotics, has predilection for the kidney and are difficult to eradicate.

Correlation Among Inhibin A And B, Anti-M Â¨Ullerian Hormone, Follicle-Stimulating Hormone, Luteinizing Hormone, And Estradiol Hormones In Infertile Women Aytan Ali, Abdullayeva; Fazil Kurbanova, Jamila
Journal of Medical Biomedical and Applied Sciences Vol 6 No 3 (2018)
Publisher : Journal of Medical Biomedical and Applied Sciences

Objective: The main purpose of this study was to assess ovarian reserve in infertile women and whether hormonal status depends on anti-MÂ¨ullerian hormone level.Study Design: This retrospective study evaluated and compared inhibins A and B, follicle-stimulating hormone, luteinizing hormone, and estradiol concentrations in 67 infertile women with anti-M Â¨ullerian hormone level <600 ng/L and in 39 infertile women with anti-MÂ¨ullerian hormone level >600 ng/L. Data were analyzed using SPSS version 20 (IBM, Armonk, NY, USA) and reported as meanÂ±standard deviation or number and percentage. The data in the study groups were nonparametric.Results: The mean concentrations of inhibin A and B and estradiol levels were lower (p<0.05) in infertile women with low anti-MÂ¨ullerian hormone level. Serum inhibin A level (p<0.01) positively correlated with inhibin B level in women with anti-MÂ¨ullerian hormone level <600 mg/mL. In women with anti-MÂ¨ullerian hormone level >600 mg/mL, negative correlations were found between inhibin A and B levels (r=0.494, R2=0.13, p<0.01) and between anti-MÂ¨ullerian hormone and inhibin B levels (r=-0.426, R2=0.149, p<0.01), but a positive correlation was demonstrated between inhibin A and anti-MÂ¨ullerian hormone levels (r=0.545, R2=0.096, p<0.01). The analyses of correlations between follicle-stimulating hormone and estradiol showed a major coefficient of correlation (r=0.545, R2=0.287, p<0.05). There was no correlation between age and anti-MÂ¨ullerian hormone.Conclusion: Differences in correlation between inhibin A and B levels in groups with different anti-M Â¨ullerian hormone levels demonstrate their importance in the evaluation of ovarian reserve in infertile women. Hence, we conclude that ovarian reserve assessment in infertile women should include not only the anti-M Â¨ullerian hormone level bwut also the inhibin A and B levels.

Task-Oriented Training In Rehabilitation of Gait After Stroke: Systematic Review Vijay ghag, Dr. Shweta; Shyam ganvir, Dr. Suvarna
Journal of Medical Biomedical and Applied Sciences Vol 6 No 3 (2018)
Publisher : Journal of Medical Biomedical and Applied Sciences

TITLE-Task-oriented training in rehabilitation after stroke: systematic review. AIM- The aim of the present study is to provide an overview of the evidence in the literature on task-oriented training to improve balance and gait of stroke survivors. BACKGROUND- Stroke is the second leading cause of death and one of the leading causes of adult disability in the Western world.One of the major purpose of the rehabilitative process it to help patients achieve as high a level of functional independence as possible within the limits of their particular impairments.Task related training (TRT) is a rehabilitation strategy that involves the practice of goal-directed, functional movements in a natural environment to help patients derive optimal control strategies for alleviating movement disorders. DATA SOURCES- A range of databases was searched to identify papers addressing taskoriented training in stroke rehabilitation, including Pubmed Papers published in English between English between April 2000 to 2015 were included. There were 5 papers in the final dataset, including. REVIEW METHOD- The selected randomized controlled trials and systematic reviews were assessed for quality. Important characteristics and outcomes were extracted and summarized. CONCLUSION- Generally, task-oriented rehabilitation after stroke has proved to be effective and relevant for stroke practice. The possible mechanism for effectiveness of task related training may be attributable to an enhancement of presynaptic inhibition of the hyperactive stretch reflexes in spastic muscles, decrease in the cocontraction of spastic antagonists, and disinhibition of descending voluntary commands to the motoneurons of paretic muscle.

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