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Anti-inflammatory Effect of Pequi Oil (Caryocar brasiliense) in Acute Respiratory Distress Syndrome Sousa,, Tawanne Costa de
Journal of Medical Biomedical and Applied Sciences Vol 1 (2014)
Publisher : Journal of Medical Biomedical and Applied Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15520/.v1i0.2

Introduction: Acute lung lesion (ALL) and the more severe form, acute respiratory distress syndrome (ARDS), are the common denominator of many diseases that can cause exaggerated lung inflammationÂ Objectives:Â The aim of this study was to analyze the anti-inflammatory action of pequi oil (Caryocar brasiliense) in an experimental model of acute lung inflammation induced in mice.Â Methods:Â Fifteen maleÂ RattusÂ novergicusÂ were divided into three groups: falsely operated (abdominal incision), sham (ischemia and intestinal reperfusion â I/R-1 without treatment); treated (I/R + pequi essential oil).Â Results: The treated group had less inflammatory cells, when compared with the sham group (p<0.001). Moreover, the results suggest that the treated group did not significantly differ from the falsely operated group.Â Conclusion:Â It is suggested that nebulized pequi oil reduces the pulmonary inflammatory response to injury resulting from the I/R-i lesion.

Prevalence Characteristics Risk Factors and Prognosis of Active Epilepsy in Children with Cerebral Palsy. A Prospective Case Control Hospital Based Study Deeb, Dr Hanan Said and Dr Walid EL
Journal of Medical Biomedical and Applied Sciences Vol 1 (2014)
Publisher : Journal of Medical Biomedical and Applied Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15520/.v1i0.3

Â Cerebral palsy is a major cause of childhood disability and has been described as one of the three most common life-long developmental disabilities in childhood. It is more prevalent in the more socio-economically deprived populations of the world. Epilepsy is said to occur in 15-90% of children with cerebral palsy and this poses additional economic and psychological stress on affected children and their families.Â Objectives:Â To study the prevalence, associated risk factors, and prognosis of seizures in children with cerebral palsy.Methods& Results:Â A prospective hospital based Case control study done over a period of two years to observe the clinical profile of epilepsy in children with cerebral palsy. Two hundred epileptic children with cerebral palsy were studied and Â their results were compared with the results of epilepsy in 55 developmentally normal children. Appropriate statistical tests were carried out using the SPSS 12 for windows software to identify significant predictors of epilepsy. Ages of all children studied were between 1-5 years. Majority were below three years of age and male outnumbered female. Spastic Tetraplegia (34.3%) was the commonest type of cerebral palsy. Generalized tonic-clonic seizure (42.8%&45.5%) was the commonest seizure type in both groups respectivey. Second most common type of seizure was partial (21.8%&21.4%) in developmentally normal and cerebral palsy children respectively. Brain atrophy (71.4%) was the commonest computed tomographic findings in cerebral palsy patients. In electro encephalography generalized epileptiform activity was the commonest finding in both groups. Clinical pattern is different in many ways when epilepsy is associated with cerebral palsy.Conclusion:Â Epilepsy is a frequent problem in children with cerebral palsy. A history of neonatal seizures, occurrence of seizures in the first year of life, presence of spastic tetraplegia and post infectious brain damage all warrant a close evaluation and appropriate follow up for early detection of epilepsy in children with cerebral palsy.Â Key words: Epilepsy, risk factors, cerebral palsy.

Bursal body Weight ratio and Histopathological changes in commercial chicks Vaccinated with a live and two killed Infectious bursal disease vaccines L. SaÃ¢Â€Â™idu3, M.T. Angani1, P.A Abdu2,
Journal of Medical Biomedical and Applied Sciences Vol 1 (2014)
Publisher : Journal of Medical Biomedical and Applied Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15520/.v1i0.4

This study was conducted to compare the bursal body weight ratio and histopathological changes in commercial chicks vaccinated with a live and two killed infectious bursal disease (IBD) vaccines. Two hundred and eighty, day old chicks were divided into four groups of seventy chicks each. Group 1, 2 and 3 were vaccinated with live vaccine, killed vaccine (A) and killed vaccine (B) respectively while group 4 was not vaccinated. Vaccination was conducted at 9 and 16 days of age. Five chicks from each group were sacrificed weekly and the bursa to body weight ratio (BBWR) were determined. Twenty chicks from each group were challenged with a very virulent infectious bursal disease virus (vvIBDV) at 30 days of age. There was no significant difference in body weight in chicks vaccinated with both live and killed IBD vaccines but there was a significant decrease in the bursal body weight ratio of chicks in group 1 after vaccination at p value of 0.0001 and after challenge at p value of 0.0002. Histopathologic lesions which include; thickened epithelium, interfollicular oedema, small sized follicles, poorly demarcated cortex and medulla and follicles sparsely populated by lymphocytes were observed in the chicks in group 1. No histopathologic lesions were observed in chicks in group 2 and 3 after vaccination but lesions were observed in group 3 after challenge. No lesions were observed inÂ group 4 prior to challenge but after challenge, lesions observed include; sloughed off epithelium, interfollicular oedema, interfollicular haemorrhages, interplica debris, follicles devoid of lymphocytes. In conclusion, the live vaccine caused bursal atrophy. Killed vaccine A and B did not have any adverse effect on the BF. Killed vaccine A is recommended for the control of IBD in Nigeria and the potential of the live vaccine to cause bursal atrophy and immunosuppression should be investigated.

Detection of Rabies Antigen in the Saliva and Brains of Apparently Healthy Dogs Slaughtered for Human Consumption in Abia State Nigeria and its Public Health Implication. Ogunkoya, A.B.,, 1Mshelbwala, P.P., 1; Abdullahi, S.U, Maikai, B.V. ,3 Nlebedum, UC
Journal of Medical Biomedical and Applied Sciences Vol 1 (2014)
Publisher : Journal of Medical Biomedical and Applied Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15520/.v1i0.5

Apparently healthy dogs could excrete rabies virus in their saliva for long period without showing signs and symptoms of the disease. Carrier status of rabies virus infection has been demonstrated in different parts of Nigeria but in Abia State, there is limited information on the status of rabies in apparently healthy dogs. The study was carried out in eight slaughter points within four Local Government Areas of the State for the determination of rabies antigen in the saliva and brain of apparently healthy dogs slaughtered for human consumption. A total of one hundred (100) samples of saliva and brain were collected before and after slaughter respectively between April to June, 2013 in the selected areas. The saliva was subjected to rapid immune-chromatographic test (RICT) while Direct Fluorescent Antibody Test (DFAT) was carried out on the brain samples. Structured questionnaire was administered to nineteen (19) dog meat processors (18 male and 1 female) in the selected areas. Sixty four percent of the samples tested were from female dogs while 36% were from males. All the dogs were sourced from surrounding villages.Â Five (5%) of the dogs tested were positive for rabies antigen with the use of both tests, signifying a total agreement between RICT and conventional DFAT. All the positive cases were detected in female dogs. 94.7% of the butchers were bitten during the course of processing, out of the 94.7% exposed to dog bite, 72.8%Â utilizeÂ traditional method of treatment while 27.8%Â reported to theÂ hospital for proper medical attention. This study has established the presence of rabies antigen in apparently healthy dogs in the study area which may signify the endemicity of the disease in the area. Hence mass enlightenment program for dog owners, marketers, processors, consumers and children within the state is highly recommended.

Diversity, Distribution and Indigenous Uses of Medicinal Plants in Parbati Valley of Kullu District in Himachal Pradesh, Northwestern Himalaya S.S. Samant2, Pankaj Sharma1* and
Journal of Medical Biomedical and Applied Sciences Vol 1 (2014)
Publisher : Journal of Medical Biomedical and Applied Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15520/.v1i0.6

In the remote areas of the Indian Himalayan Region, the inhabitants largely depend on medicinal plants for curing diseases and income generation. But, proper documentation of the medicinal plants has been poorly attempted. The value of medicinal plants in traditional healthcare practices provides clues to latest areas of research in biodiversity conservation. Keeping this in view, the present study has been conducted to study the diversity, distribution and indigenous uses of medicinal plants of Parbati valley in Kullu district of the Himachal Pradesh. A total of 402 species of medicinal plants belonging to 98 families and 266 genera were recorded and used by the inhabitants of the area for curing various ailments. These medicinal plants comprise of 34 trees, 301 herbs, 61 shrubs, and climbers and ferns, 03 species, each. Maximum medicinal plants were reported in the altitudinal zone, 1100-1800m and decreased with increasing altitudes in the study area. Of the total medicinal plants, 207 were natives, 04 endemic and 44 near endemic. The continued over-exploitation, habitat degradation and changing environmental conditions may lead to the extinction of these species within a few years. Therefore, regular monitoring of population and habitats using standard ecological methods, development of conventional andÂ in-vitropropagation protocols, establishment of species inÂ in-situÂ andÂ ex-situÂ conditions have been suggested.

Impact of Corporate Governance in Solving the Challenges Faced by Family Business Transitions: Case Study of Pakistan Fareeha Zafar, Zara Usmani,
Journal of Medical Biomedical and Applied Sciences Vol 1 (2014)
Publisher : Journal of Medical Biomedical and Applied Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15520/.v1i0.7

This research paper centers on the challenges faced in transferring and sustaining the family business to the next generations in Pakistan. Family businesses are mostly Small and Medium Enterprises SMEâs and our thought to be the backbone of every economy. This paper talks regarding the increasing number of family business in Pakistan. Family businesses are facing many challenges due to the rising growth and globalization of economies. The way businesses tackle with these challenges can be the reason for their success and failure. By incorporating good corporate governance framework and systems many of the challenges can be eradicated. In this paper, the significance of corporate governance in family owned business is identified. This study looks at the theoretical background of corporate governance and its inculcation in the family businesses of Pakistan. Family businesses play a major role for economic growth in Pakistan. This study aims to emphasize that for a sustainable family businesses and their perpetual growth, good corporate governance must be introduced in such entities. In addition to family owners more non-family employees and managers should be hired in the business, so that business is managed more justly and efficiently without any biasness keeping in mind the business laws and codes. Corporate governance will ensure that FOBs are transparent enough to satisfy its various stakeholders such as supplierâs customers and creditors.

Human resource Role in Change management During cross border Mergers Yousaf Iqbal,, Dr. Fareeha Zafar
Journal of Medical Biomedical and Applied Sciences Vol 1 (2014)
Publisher : Journal of Medical Biomedical and Applied Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15520/.v1i0.8

Human resource in todayâs age and time has a strategic role to be played in change processes. The following paper analyzes the key factors that can lead for a successful merger and how HR can assist in this change. The 2Câs namely culture and communication holds the key for success and failure depending upon the implied strategy by the top management and its application by the HR department. Moreover, change management and mergers have been analyzed with case studies from cross border mergers.

Integrating Strategies of Entrepreneurship- Gourmet Pakistan case study from Pakistan Zafar, Muhammad Ali
Journal of Medical Biomedical and Applied Sciences Vol 1 (2014)
Publisher : Journal of Medical Biomedical and Applied Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15520/.v1i0.9

This paper aims to get to know how integrating strategies boost up entrepreneurship. The study has shown that the dynamics of prevailing market structure, Applying creativity to develop innovation, culture, entrepreneurial leadership, economic transition, networking structures its stages and management resources are key integrating strategies for entrepreneurship. Moreover, capital and tax polices play a vital role in boosting up entrepreneurship.Study of Gourmet Pakistan gives strong support that mentioned strategies boost up the entrepreneurial process. The researchmethodology used in this paper is face to face interview, financial reports & official website of Gourmet Pakistan.

Interactive role of climate change on Economic growth Farooq, Ammara
Journal of Medical Biomedical and Applied Sciences Vol 1 (2014)
Publisher : Journal of Medical Biomedical and Applied Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15520/.v1i0.10

Climate change is a very uncertain and complex external phenomenon that affects the economic growth. The purpose of this paper is to study the role of climatic changes on economic growth globally as the climate effects are very crucial to evaluate the economic growth. Climate change has significant effects on the economy hence on the economic growth. In order to study the effect of climate change, all the effects of climate change will be discussed followed by the factors of economic growth and their interactive effect will be analyzedÂ

Menstrual Blood Banking: A concept âbest out of wasteâ in the area of stem cell research Ancy Mathew, Frincy Francis, Sheeba Elizabeth Joel,
Journal of Medical Biomedical and Applied Sciences Vol 3 (2016)
Publisher : Journal of Medical Biomedical and Applied Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15520/.v3i0.11

The primitive cells also known as the stem cells are miraculous cells that can regenerate into various organs such as the heart, bones, muscles and nervous system. The emergence of stem cell technology and the successful impact of the stem cells research has brought ray of hope to the diseased population of the world. Remarkable responses have been created in the medical specialties by stem cell therapies with the most popularized concept of cord blood which has helped in many major diseases like Thalassemia, Alzheimerâs disease. Likewise stromal cells of menstrual origin or Menses-Menstrual Blood âDerived Stem Cells have demonstrated cells to be equally multi potent like the umbilical cord blood and the dental pulp stem cells except for the myth among the public that the menstrual blood is a bad blood that needs to be discarded. Menstrual stem cells could offer a lot of advantages over the other stem cells as the source is easy to find because every woman is a source, quantity available is more, the fear of tissue rejection is minimal and above all the question of ethical issues related to using embryonic stem cells are avoided. Researchers across the globe have come to a conclusion that the cells derived from menstrual blood may represent a potentially unlimited, easily available and cost effective source used in regenerative therapies. The electronic databases using which was done were Cumulative Index to Nursing and Allied Health Literature (CINAHL), Medical Literature Online (Medline), Pub med, EBSCO, Embase, and Science Direct. The search terms include Menstruation, Menstrual Blood, and Menstrual Blood Stem Cells. Menstrual Blood Banking, Endometrial Stem Cells. Menstrual Regenerative Cells. Menstrual Blood Banking appears to be an innovative, promising, cost effective, novel and ethically acceptable alternative concept which needs to be popularized in the field of medicine.

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