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Journal of Medical Biomedical and Applied Sciences

jmbas
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Published by Innovative Journal

ISSN : - EISSN : - DOI : -

Core Subject : Health, Science,

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

Arjuna Subject : -

Articles 8 Documents

Search results for , issue " Vol 6 No 9 (2018)" : 8 Documents clear

Bioinformatics Technology In Clinical And Public Health Microbiology Applying Computational Methods Kim, Hyunjo
Journal of Medical Biomedical and Applied Sciences Vol 6 No 9 (2018)
Publisher : Journal of Medical Biomedical and Applied Sciences

The role of clinical genomics in infectious disease diagnostics and public health microbiology is the topic of discussion during a recent decade. Although much of this work is aimed at describing the structure of outbreak communities, the methodology works equally well to identify pathogens in clinical samples. Clinical genomics is the exploitation of genome sequence data for diagnostic, therapeutic, and public health purposes. Central to this field is the high-throughput DNA sequencing of genomes and metagenomes. The key concept in using clinical genomics methodology is that detection of microbes is independent of culture and is not limited to targets used for in-depth PCR assays. Rather, it is a process of generating large-scale sequence data sets that adequately sample a specimen for microbial content and then of applying computational methods to resolve the sequences into individual species, genes, pathways, or other features.

Accuracy of 12 Lead ECG For Diagnosis of Posterior Myocardial Infarction Taking 15 Lead ECG As Gold Standard Panezai, Sikander Azeem; Azim, Waqar; Kakar, Kaleemullah; khan, Alamzeb; Tareen, Sehrish Ghani; Tareen, Zarghoona
Journal of Medical Biomedical and Applied Sciences Vol 6 No 9 (2018)
Publisher : Journal of Medical Biomedical and Applied Sciences

INTRODUCTIONThe acute management of ST-elevation myocardial infarction (STEMI) is based on interpretation of the ECG. Thisis typically undertaken by doctors in the emergency department (ED) and acute medical unit. Increasingly, the ECGdiagnosis is being made by paramedics, allowing them to pre-alert the ED or even initiate thrombolytic therapy inregions where primary angioplasty is unavailable. Identification of ST-segment elevation or presumed new left-bundlebranch block in combination with a history of cardiac chest pain results in prompt initiation of reperfusion therapy.SUBJECT AND METHODA cross sectional study was done at Cardiology Department, Bolan Medical College, Quetta. Total duration was from01/02/2018-30/07/2018. 196 patients were recruited from Out Patient Department and Emergency Department of BolanMedical Complex, Quetta on the basis of inclusion/exclusion criteria, that is all patient with chest pain and age >18 and< 70 with posterior MI as per operational definition presenting within 12 hours of symptoms were included and allpatients with underlying LBBB on ECG, PPM and paced rhythm on ECG and pericardial effusion were excluded asthey are effect modifiers and bring bias in study.RESULTSTotal 196 patients were included in the study according to the inclusion criteria of the study. Mean age (years) in thestudy was 40.28+14.38 whereas there were 123 (62.8) male and 73 (37.2) female patients in the study. The diagnosticaccuracy, sensitivity, specificity, PPV and NPV of 12 lead ECG for diagnosis of posterior myocardial infarction taking 15lead ECG as gold standard was 82.14%, 87.12%, 57.58%, 91.03% and 47.50% respectively.CONCLUSIONThe study concludes that diagnostic accuracy of 12 lead ECG for diagnoses of posterior wall myocardial infarction washigh. The high sensitivity identified more patients to be re vascularized early.

Mitochondrial neuropathy in pediatric patients carrying mtDNA, POLG1, SURF1, and PDHA1 mutations Finsterer, MD, PhD, Josef; Zarrouk-Mahjoub, PhD, Sinda
Journal of Medical Biomedical and Applied Sciences Vol 6 No 9 (2018)
Publisher : Journal of Medical Biomedical and Applied Sciences

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Postnatal Prognosis of Fetal Noncompaction Is Uncertain In Sibs Carrying a PKP2 Deletion Finsterer, MD, PhD, Josef; Zarrouk-Mahjoub, PhD, Sinda
Journal of Medical Biomedical and Applied Sciences Vol 6 No 9 (2018)
Publisher : Journal of Medical Biomedical and Applied Sciences

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Toxoplasma Gondii Stimulates The Behavioural Changes of Rodents: Updated Evidence Che Omar, Siti Shafiyyah; Mohd Moklas, Mohamad Aris; Mohtarrudin, Norhafizah; Osman, Malina
Journal of Medical Biomedical and Applied Sciences Vol 6 No 9 (2018)
Publisher : Journal of Medical Biomedical and Applied Sciences

In recent years, there have been an increased number of reports in the literatures on animal behavioural changeslinked with intracellular protozoan Toxoplasma gondii. Evidence for animal behavioural changes with Toxoplasmagondii infection comes from experimental tests on animal models such as mice and rats. These studies describethe important mechanisms of behavioural changes which involving neuromodulator and neurotransmitter level.Furthermore, behavioural changes also have been identified in human as well as animal models that may also playa role in development of schizophrenia in humans

Dressing Out Percent And Some Carcass Characteristic of EL Gash Sheep M. O. M, Omer; A.N, Ekhlas; O.M.A, Atif
Journal of Medical Biomedical and Applied Sciences Vol 6 No 9 (2018)
Publisher : Journal of Medical Biomedical and Applied Sciences

This study was conducted to evaluate dressing out percent and carcass characteristic potentials of EL Gash sheep,under their natural habitat in Kassala town abattoir, Thirty , sheep 15 males and 15 females , were purchased formthe different local market of El Gash Area. Each sex was comprised of five groups , according to the age studied .live animals body weights were be taken before and after slaughtering .The evaluation of dressing out percent carcassyield characteristic were be taken. The slaughter data results significant difference between the two sexes . The resultindicated that dressing out percentage were 49.4% and 47.3% for the male and the female respectively with overallaverage of 48% . Slaughter at different ages showed significant differences in some parts of internal organs betweenthe two sexes. Alive weight, muscle, bone, trims, head, skin, rumen full, intestine full intestine empty, liver, heart, lungsreproductive organs and spleen were heavier in male than the female it might be due to the sex male hormone, butmesenteric fat, omentum fat, kidney knob canal fat [k.k.c.f], and fat were heavier in female than the males while muscle,bone, fat, trims, head, mesenteric fat, omentum fat, spleen and knob canal fat (k.k.c.f)were significant.

Familial Noncompaction In Holt-Oram Syndrome Finsterer, MD, PhD, Josef; StÃƒÂ¶llberger, MD, Claudia
Journal of Medical Biomedical and Applied Sciences Vol 6 No 9 (2018)
Publisher : Journal of Medical Biomedical and Applied Sciences

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Bioinformatics Tools In Clinical Microbiology and Infectious Disease Prevention Algorithms Kim, Hyunjo
Journal of Medical Biomedical and Applied Sciences Vol 6 No 9 (2018)
Publisher : Journal of Medical Biomedical and Applied Sciences

Bioinformatics resource is the exploitation of genome sequence data for diagnostic, therapeutic, and preventionpurposes. The role of clinical genomics in infectious disease is aimed at describing the structure of outbreakcommunities, the methodology works equally well to identify pathogens in clinical samples. Furthermore, early detectionof infectious disease in outbreaks is one of the significant issues in syndromic surveillance systems. The key concept inusing clinical genomics methodology is a process of generating large-scale sequence data sets that adequately samplea specimen for microbial content and then of applying computational methods to resolve the sequences into individualspecies, genes, pathways, or other features. It helps to provide a rapid epidemiological response and reduce morbidityand mortality. Therefore, bioinformatics model algorithms for virus transmission and prevention in terms of resistomewould be taken into consideration. The relevant future study of resistome reveals strategies that can be applied in newantibiotic discoveries.

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