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INDONESIA
Health Notions
Published by Humanistic Network for Science and Technology
ISSN : 25804936     EISSN : -     DOI : -
Core Subject : Health,
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health
"Health Notions" is a media for the publication of articles on research and review of the literature. We accept articles in the areas of health science and practice such as public health, medicine, pharmaceutical, environmental health, nursing, midwifery, nutrition, health technology, clinical laboratories, health education, and health popular.
Arjuna Subject : -
Articles 21 Documents
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Search results for , issue "Vol 1, No 4 (2017): October-December" : 21 Documents clear
The Role of Nutritional Status, Dietary Pattern and Free Radical in the Insulin Resistance Development Meirna Dewita Sari; Bambang Wirjatmadi; Merryana Adriani
Health Notions Vol 1, No 4 (2017): October-December
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (383.009 KB) | DOI: 10.33846/hn.v1i4.79

Abstract

Insulin resistance is an early sign of diabetes type 2 that occurs in situations where target organ sensitivity decreases against insulin. Excess free radicals can be mutually insulin resistance. The purpose of this study was to determine how the effects of insulin can be a determining factor. This study used case control design conducted on 22 outpatients at Clinic University of Muhammadiyah Surabaya during June until July 2017. Data were collected using questionnaires, nutritional status, fasting blood glucose, fasting insulin, and MDA levels. Insulin resistance status using normal HOMA IR method of <2.77. Logistic Regression was used to determine the effect of free radical on the occurrence of insulin resistance. The results showed free radical against insulin resistance at =0.05 with p=0.018. That result means boosting MDA levels also increases the risk of insulin resistance. In addition, the consumption of dietary sources of fat and excessive use of food additives, low fruit intake, BMI values are also factors affecting insulin resistance with p=0.027; p=0.036; and p=0.027. Given the elevated levels of MDA-free radicals can increase the risk of insulin resistance. Applying a healthy lifestyle by consuming fiber-rich foods can prevent the formation of excessive free radicals. Keywords: Insulin resistance, Free radical, HOMA IR

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