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Journal of Applied Pharmaceutical Research
Published by Creative Pharma Assent
ISSN : -     EISSN : 23480335     DOI : 10.18231
Core Subject : Health,
Medicine & Pharmacology
Journal of Applied Pharmaceutical Research (JOAPR) is an official publication of Creative Pharma Assent (CPA). It is an open access, peer review online international journal. JOAPR is primarily focused on multiple discipline of pharmaceutical sciences (Pharmaceutics, Pharmaceutical Technology, Biopharmaceutics, Cosmetic Technology, Pharmacokinetics, Pharmaceutical/Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmacognosy and Phytochemistry, Herbal drugs/ formulations, Pharmacology, Pharmaceutical Analysis, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics and Biotechnology of Pharmaceutical Interest) which publish quarterly. JOAPR also includes evaluation of pharmaceutical excipients & their practical application to research & industry based efforts. The aim of the scientific journal, JOAPR is to present a wide area for the current researchers to share their noble works and ideas in terms of the research papers, review articles and short communications. JOAPR only publish the original research works with a definite innovation and novelty after thorough reviewing. The paper must have a suitable and proper scientific background.
Arjuna Subject : -
Articles 2 Documents
 1 
Search results for , issue " Vol 4 No 3 (2016)" : 2 Documents clear
FORMULATION AND CHARACTERIZATION OF ORGANIC- INORGANIC HYBRID FILM FOR TRANSDERMAL DRUG DELIVERY Taksande, Jayshree Brijesh; Gupta, Mona; Trivedi, R V; Wadher, K J; Umekar, M J
Journal of Applied Pharmaceutical Research Vol 4 No 3 (2016)
Publisher : Creative Pharma Assent

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Abstract

A novel organic–inorganic hybrid film-forming gel for transdermal application was developed by poly vinyl alcohol using Di methyl polysiloxane as an inorganic-modifying agent, poly N-vinyl pyrrolidone as a tackifier and PEG 200 as a plasticizer. The hybrid film-forming gel can be directly applied on the skin forms a thin bioadhesive film with transparent and non- greasy feeling. The mechanical and bioadhesive properties of films produced from the hybrid gels were investigated and the results showed that the incorporation of appropriate Di methyl polysiloxane into the PVA matrix significantly improves the mechanical strength and skin adhesion properties of the resulting film.  In conclusion, the bioadhesive films formed from organic–inorganic hybrid gel holds excellent qualities for application on the skin and may provide a promising formulation for transdermal delivery of drugs, especially when the patient acceptability from an aesthetic perspective of the dosage form is a main consideration.
Pharmacognostic Evaluation and Physico-chemical Analysis of Ulmus wallichiana Planch. Bora, Kundan Singh; ., Akhilesh
Journal of Applied Pharmaceutical Research Vol 4 No 3 (2016)
Publisher : Creative Pharma Assent

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Abstract

The plant Ulmus wallichiana Planch. (Family: Ulmaceae) is found in Himalayan regions from Afghanistan to West Nepal. In India, it is found in Kumaun and Garhwal hills of Uttarakhand (India), locally known as Chamarmou. Bark of U. wallichiana is commonly used as Kumauni and Garhwali traditional healers for bone fracture of animals as well as human being. The current work was designed to establish the pharmacognostic parameters like macroscopic & microscopic characters, and physico-chemical analysis for U. wallichiana. WHO recommended methods and other standard procedures were employed for the establishment of pharmacognostic and physico-chemical parameters. Transverse section (TS) of the bark under the microscope showed periderm region showing cortex, mucilage canal, cork, phellogen and phelloderm. TS of the bark also showed secondary phloem region, medullary rays, stone cells and fibres. Longitudinal section showed medullary region, epidermal region and mucilage canal. Powder microscopy under the microscope showed calcium oxalate crystals, cork cells, phloem fibre, starch grains, stone cells and lignified phloem fibres. Physico-chemical analysis helps to identify pure plant material and detect adulteration. In the present study, total ash, water soluble ash, acid insoluble ash, sulphated ash and loss on drying were estimated to be 17%, 15%, 3.5%, 5%, 0.15% respectively. The findings of the present study could be useful in authentication of plant material and also in monograph preparation of U. wallichiana.

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