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Journal of Applied Pharmaceutical Research
Published by Creative Pharma Assent
ISSN : -     EISSN : 23480335     DOI : 10.18231
Core Subject : Health,
Medicine & Pharmacology
Journal of Applied Pharmaceutical Research (JOAPR) is an official publication of Creative Pharma Assent (CPA). It is an open access, peer review online international journal. JOAPR is primarily focused on multiple discipline of pharmaceutical sciences (Pharmaceutics, Pharmaceutical Technology, Biopharmaceutics, Cosmetic Technology, Pharmacokinetics, Pharmaceutical/Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmacognosy and Phytochemistry, Herbal drugs/ formulations, Pharmacology, Pharmaceutical Analysis, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics and Biotechnology of Pharmaceutical Interest) which publish quarterly. JOAPR also includes evaluation of pharmaceutical excipients & their practical application to research & industry based efforts. The aim of the scientific journal, JOAPR is to present a wide area for the current researchers to share their noble works and ideas in terms of the research papers, review articles and short communications. JOAPR only publish the original research works with a definite innovation and novelty after thorough reviewing. The paper must have a suitable and proper scientific background.
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Articles 5 Documents
 1 
Search results for , issue "Vol. 5 No. 1 (2017)" : 5 Documents clear
Short review on domperidone tablet Sharma, Shaveta; Chandel, Diksha; Sudan, Puneet; Jain, Upendra K.
Journal of Applied Pharmaceutical Research Vol. 5 No. 1 (2017)
Publisher : Creative Pharma Assent

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Abstract

Oral route is presently the gold standard in the pharmaceutical industry where it is regarded as the safest, most economical and most convenient method of drug delivery resulting in highest patient compliance. Pediatric and geriatric patients find it difficult to swallow solid dosage forms like tablets. Mouth dissolving tablet that dissolve or disintegrate rapidly in oral cavity result in solution, is an ultimate remedy for this problem in addition they give pleasing mouth feeling. ODT has advantages such as patient compliance, quick onset of action, improved bioavailability. Domperidone tablet (ODT) gives relief from nausea, vomiting. This review gives us all information about pharmacokinetic, pharmacodynamic, uses, precautions, side effects of domperidone tablets
A nanocrystal technology: to enhance solubility of poorly water soluble drugs Mirza, R M; Ahirrao, S P; Kshirsagar, S. J.
Journal of Applied Pharmaceutical Research Vol. 5 No. 1 (2017)
Publisher : Creative Pharma Assent

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Abstract

Most of the recently developed new chemical entities are poorly water soluble and they create major problems during formulation and development of new dosage form and due to poor solubility and poor bioavailability. The drugs belong to BCS class II and class IV has problem of solubility, to overcome the solubility problem nanotechnology is most useful technique. In this review article the main focus on Nanocrystals and various techniques used for preparation of Nanocrystals. Drug nanocrystals consists pure poorly water soluble drugs without any matrix material which means that it is carrier free drug delivery. Nanocrystals technologies have been introduced as advantageous, universal formulation approaches for the BCS class II and IV drugs. Nanocrystals, with greater surface to volume ratio, can effectively increase both the dissolution rate and saturation solubility of active ingredients The Nanocrystals is suitable drug delivery system for all commonly used routes of administration such as oral, IV, SC, and IM and topical application. Nanocrystals can also be incorporated into the tablets, capsules, fast-melts and lyophilized for sterile product applications. There are no of techniques which are used for production including precipitation, milling, high pressure homogenization and combination methods such as Nano-Edge, SmartCrystal and Precipitation-lyophilization-homogenization (PLH) technology.
In – vitro anti tubercular activity of flowers of Couroupita guanensis L Aravind, D Sai; Karthikeyan, R; Babu, P Srinivas
Journal of Applied Pharmaceutical Research Vol. 5 No. 1 (2017)
Publisher : Creative Pharma Assent

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Abstract

Modern civilization is facing hundreds of disorders associated with microorganisms. The natural phytochemicals from non-edible plants are gaining importance to fight against these disease The intention of this study is to evaluate the ethanol and dichloromethane extracts of flower of Couroupita guianensis (Lecithydaceae) for anti-tubercular activity. The anti-tubercular activity of all the extracts of Couroupita guianensishave been evaluated against Mycobacterium tuberculosis H73Rv strain using Microplate Alamar Blue Assay (MABA). The activity was documented within MIC range of 0.8 to 100μg/ml. The results of MABA showed that both ethanol and dichloromethane extract exhibited significant anti-tubercular activity. The present investigation suggests that Couroupita guianensis possess remarkable anti-tubercular activity
Bioelectrode based chitosan-nano copper oxide for application to lipase biosensor Bodade, A B; Taiwade, M A; Chaudhari, G N
Journal of Applied Pharmaceutical Research Vol. 5 No. 1 (2017)
Publisher : Creative Pharma Assent

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Abstract

Chitosan (Chit)-nanocrystalline CuO composite prepared from Chitosan and CuO nanoparticles by a spin coating method. CuO nanoparticles (45 nm) synthesized by Sol-gel citrate method and characterized by X-Ray diffraction (XRD), Raman spectroscopy, UV-visible spectroscopy, Fourier transform spectroscopy (FTIR) and Scanning electron microscopy (SEM). The electrochemical studies revels that these Chit-nano CuO electrode provide favorable condition for immobilization of enzyme lipase [LIP] specific enzyme for triglyceride detection, resulting in enhanced electron transfer at the interface. The prepared bioelctrode (LIP/Chit-nano CuO/Au bioelectrode) is utilized for triglyceride [TG] sensing using cyclic voltammetry (CV) with hexacyanoferrate as mediator. The electrochemical response studies shows on improved sensing performance of bioelectrode exhibit high sensitivity, low detection limit and good linearity of tributyrin concentration with fast response time. The low value of Michallis-Menten constant indicates high affinity of LIP towards the analyte (tributyrin). The Redox behavior of nano CuO makes an efficient matrix with chitosan for triglyceride [TG] biosensor.
A review on the pros and cons of online Pharmacies Jain, V H; Tadv, S A; Pawar, S P
Journal of Applied Pharmaceutical Research Vol. 5 No. 1 (2017)
Publisher : Creative Pharma Assent

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Abstract

Now a day’s buying a medicine online is common practice across the globe, because buyers are used to order for medicines through a click of a button rather than taking a trip to a drug store. Such online websites sell everything from prescription drugs to health related products. Most of such stores are legal outlets that safeguard all traditional procedures related to drug prescription. That is why most buyers are confident about dealing with these stores. But there are quite a few rogue stores that have come up in the recent past over the internet. These stores deal in illegal medications and unapproved drugs, buyers must be aware of such rogue stores. The fact remains that drugs purchased at online drug stores offer high levels of handiness, put forward privacy for the buyer as well as safeguard traditional procedures of prescribing drugs. Thus consumers can use these services with the same confidence as they would have had in the neighbourhood pharmacist. But they must stay away from "rogue sites" that sell unapproved products or sidestep conventional procedures that safeguard the interests of consumers. Additionally, customers have difficulty knowing whether an Internet pharmacy is a legitimate operation.

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