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JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice)
Published by Universitas Gadjah Mada
ISSN : 20888139     EISSN : 24432946     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
JMPF is the first open access journal in Indonesia specialized in both research of pharmaceutical management and pharmacy practice. Articles submitted in JMPF are peer reviewed, we accept review articles and original research articles with no submission/publication fees. JMPF receives manuscripts in both English (preferably) and Indonesian Language (Bahasa Indonesia) with abstracts in bilingual, both Indonesian and English. JMPF is also open for various fields such as pharmaceutical management, pharmacoeconomics, pharmacoepidemiology, clinical pharmacy, community pharmacy, social pharmacy, pharmaceutical marketing, goverment policies related to pharmacy, and pharmaceutical care.
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Articles 10 Documents
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Search results for , issue "vol 16, no 2" : 10 Documents clear
Multiple Criteria Decision Analysis for Off-Patent Pharmaceuticals in Health Care: Bibliometric Analysis and Scoping Review Ratih Puspita Febrinasari; Erna Kristin; Aiman Hilmi Asaduddin; Meutia Filzan Kamilah; Dinari Febriyanti
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 16, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.100349

Abstract

Background: Multi-Criteria Decision Analysis (MCDA) is a structured approach used for evaluating complex decisions that involve multiple criteria. In the context of healthcare, its use has grown significantly for benefit–risk assessments, formulary decisions, and reimbursement processes. In developing countries, MCDA has been proposed to support evidence-based evaluation of off-patent pharmaceuticals (OPPs), helping improve public health outcomes and access to quality medicines. However, existing reviews remain limited in scope, emphasizing the need for an updated bibliometric overview of MCDA applications in OPPs.Objectives: This study aims to provide a comprehensive bibliometric analysis of MCDA research in healthcare, with a specific focus on OPPs.Methods: Searches were conducted in Scopus, PubMed, and Epistemonikos from January 1985 to October 2023. Eligible studies included full-text English articles utilizing MCDA in OPP procurement. Data were extracted on decision contexts, criteria, methodologies, and stakeholder involvement. Bibliometric analysis was conducted using Scopus Analyzer, VOSviewer, and Microsoft Excel.Results: A total of 2,210 MCDA-related healthcare articles were identified from 1981 to 2023, with a marked increase after 2013. Dominant themes included decision-making, multicriteria analysis, and healthcare. The identification results showed that A.A. Zaidan was the most prolific author. Citation analysis reported 41,882 citations between 2011 and 2023. The scoping review identified seven studies focusing on MCDA for OPPs, highlighting quality as the most prioritized criterion in procurement frameworks.Conclusion: MCDA frameworks offer a comprehensive approach to improve healthcare decision-making and policy development, particularly in evaluating and procuring OPPs, while supporting adaptable implementation across diverse health systems.
Effectiveness and Limitations of Spiramycin for Toxoplasmosis During Pregnancy: A Systematic Review Noor Laila Harkaningdyah; Salma Auliya Fatimah; Ayu Anggresti; Lavia Dinta Nur Pratiwi; Nabila Risti Rachmadi; Andi Desiah Pranada
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 16, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.100761

Abstract

Background: Toxoplasmosis is brought on by the protozoan parasite Toxoplasma gondii. Toxoplasmosis can be transferred from a mother to her fetus during pregnancy, resulting in congenital illness. Spiramycin is administered in the early stages as a kind of prophylaxis for the fetus and can be continued until delivery. If the fetus becomes infected, therapy is altered to a triple mixture of sulfadiazine, folinic acid, and pyrimethamine.Objectives: This article aims to comprehensively review spiramycin as a prophylactic measure for preventing vertical transmission of infection to fetuses and its limitations, including adverse effects.Methods: This study used a systematic review approach of publications indexed in Scopus, PubMed, ScienceDirect, and Web of Science databases from 2014 to 2024. It utilized the PRISMA flow diagram to guide the article selection process until a conclusion was reached.Results: Based on the predetermined inclusion and exclusion criteria and in accordance with the topic of this research objective, six research articles were suitable for review. Among the six reviewed articles, spiramycin is the first-line therapy for preventing vertical transmission of Toxoplasma gondii to the fetus. The most common side effect of using spiramycin in pregnant women is paresthesia.Conclusion: Spiramycin has an important role in preventing congenital toxoplasmosis, but it is not recommended for infected fetuses. Instead, combination therapy is superior for treating infections that have occurred in the fetus.
Effectiveness of Opioids-Adjuvant Analgesics Combinations for Pediatric Cancer Pain: A Systematic Review Ulfa Filliana; Susi Ari Kristina; Bekti Meilani Nurcahya
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 16, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.100789

Abstract

Background: The pediatric cancer was reported that they got worst pain and 40% weren’t managed well. The impact of untreated cancer pain is low quality of life and poor pain experienced. Therefore, it is important to know the best analgesic for improving the clinical outcome of pain.Objectives: This study aims to determine the effectiveness of using opioid combined with adjuvant analgesics based on WHO analgesic ladder in pediatric cancer pain.Methods: PubMed and Science Direct were searched for randomized controlled trials and retrospective studies by the keyword’s “opioid”, “adjuvant analgesic”, “pediatric”, “cancer” within 2014-2024. The primary outcome was using Faces Pain Scale, or visual analog scale (VAS), or numerical rating scale (NRS).Results: A result of 556 studies were reviewed. After further inspection of collected studies, only 5 studies achieved all inclusion criteria. The final studies consist of two prospective studies with randomized trial and three retrospective studies. Combination gabapentin or pregabalin as adjuvant analgesic with opioids was better reduced pain intensity and less adverse events than other combinations.Conclusion: This study supports the increased effectiveness of analgesic opioid combined with adjuvant analgesics, compared with single opioid, in the treatment of pediatric cancer pain. Further study inspires researchers to conduct studies using the randomized trial method and continue meta-analysis study especially in pediatric population and developing countries.
Comparing the Effectiveness of Metformin–Acarbose and Metformin–Sulfonylurea Combination Therapies in Patients with Type 2 Diabetes Mellitus at Diponegoro National Hospital Syarifah Khaerunnisa; Eva Annisaa'; Fitri Wulandari
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 16, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.101082

Abstract

Background: Diabetes mellitus is a major non-communicable disease and accounts for approximately 4% of deaths in Indonesia. The effectiveness of type 2 diabetes mellitus (T2DM) treatment is generally evaluated using HbA1c, fasting blood sugar (FBS), postprandial blood sugar (PPBS), and the incidence of hypoglycemia—the most concerning complication. Multiple combination therapy regimens are available, each with varying levels of effectiveness.Objectives: This study aimed to compare the effectiveness of metformin–sulfonylurea and metformin–acarbose combination therapies in T2DM patients, as measured by HbA1c, FBS, PPBS, and hypoglycemia incidence at Diponegoro National Hospital.Methods: A cross-sectional observational study with a retrospective design was conducted. Secondary data were collected between January 2021 and June 2023 using purposive sampling. Eligible patients had received regular drug therapy for at least three months.Results: Among patients receiving metformin–sulfonylurea, glycemic control was achieved in 82.3% for FBS, 82.3% for PPBS, and 48.4% for HbA1c, with 82.3% showing no hypoglycemia. In patients receiving metformin–acarbose, glycemic control was achieved in 66.1% for FBS, 67.7% for PPBS, and 32.3% for HbA1c, with 96.8% showing no hypoglycemia.Conclusion: Significant differences in effectiveness were observed between metformin–sulfonylurea and metformin–acarbose with respect to FBS and hypoglycemia incidence, whereas no significant differences were found for PPBS and HbA1c. These findings suggest that both regimens are generally effective. Metformin–sulfonylurea may be preferred when stricter glycemic control is desired, while metformin–acarbose may be more suitable for patients at higher risk of hypoglycemia.
Cost-Effectiveness Analysis of Amlodipine–Candesartan and Amlodipine–Furosemide in Hypertensive Inpatients at RSUD Dr. Loekmono Hadi Kudus, 2023 Yulia Pratiwi; Mutia Arum Masitoh; Annis Rahmawaty; Mersi Riyanti
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 16, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.103302

Abstract

Background: Hypertension is a major public health problem and a leading risk factor for cardiovascular morbidity and mortality. In hospitalized patients, combination antihypertensive therapy is frequently used to achieve optimal blood pressure control, which may lead to increased healthcare costs. Therefore, evaluating the cost-effectiveness of commonly used antihypertensive combinations is essential to support rational drug selection in hospital settings.Objectives: This study aims to analyze the cost-effectiveness of amlodipine–candesartan and amlodipine–furosemide combination therapies for inpatient hypertension treatment at RSUD dr. Loekmono Hadi Kudus in 2023.Methods: This non-experimental, descriptive study employed a retrospective design using medical record and cost data from 88 hypertensive inpatients. Patient characteristics, length of hospital stay, therapeutic effectiveness, and direct medical costs were analyzed. Therapeutic effectiveness was defined as the proportion of patients achieving target blood pressure based on JNC VIII guidelines. Cost-effectiveness was assessed using the Average Cost-Effectiveness Ratio (ACER) and Incremental Cost-Effectiveness Ratio (ICER).Results: The amlodipine–candesartan combination demonstrated a lower ACER (Rp48,229 per 1% effectiveness) than amlodipine–furosemide (Rp90,275). The ICER value (−Rp597,651) indicated that amlodipine–candesartan was both more effective and less costly. Higher costs in the amlodipine–furosemide group were associated with injectable drug use and a greater proportion of prolonged hospital stays.Conclusion: Amlodipine–candesartan was more cost-effective than amlodipine–furosemide for managing hypertensive inpatients. These findings support the preferential use of amlodipine–candesartan when clinically appropriate to optimize both clinical outcomes and healthcare resource utilization.
Efficiency of Drug Inventory Control in Hospitals in Indonesia Using the Minimum-Maximum Stock Level: A Systematic Review Putu Hediarta Widiana Putra; Satibi Satibi; Susi Ari Kristina
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 16, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.106600

Abstract

Background: Efficient drug inventory management in hospitals is crucial for ensuring the availability of necessary medications while avoiding excessive costs and storage challenges. In developing countries, pharmaceuticals account for 40–50% of total hospital expenditures, highlighting the importance of inventory control. The Minimum-Maximum Stock Level (MMSL) method is a straightforward approach to managing hospital drug inventory that prevents overstocking and causes reorders to avoid shortages.Objectives: This study aims to evaluate the impact of the MMSL method on drug inventory control efficiency in hospitals in Indonesia.Methods: This systematic review was conducted following the PRISMA Statement guidelines. Articles were identified from PubMed, Scopus, Garuda, and Google Scholar databases. Studies conducted in hospitals in Indonesia that evaluated the implementation of the MMSL and reported efficiency indicators such as inventory value, Inventory Turnover Ratio (ITOR), stockout, and dead stock were included. The methodological quality of the selected studies was assessed using the JBI critical appraisal tools.Results: A total of seven reviewed articles showed that the MMSL method positively influenced the efficiency of drug inventory control in hospitals, as evidenced by reductions in drug inventory values, increases in ITOR, decreases in stockout frequency and value, and a reduction in dead stock. In another study, ITOR decreased at a government hospital, although it remained within the ideal value range.Conclusion: The MMSL method enhances the efficiency of drug inventory management and can be implemented in hospitals in Indonesia.
Bibliometric Analysis on the Impact of Electronic Medical Records Implementation on Prescribing Errors: Trends and Research Gaps Karla Rochyana Heliati; Elsye Maria Rosa; Kusbaryanto Kusbaryanto
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 16, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.106886

Abstract

Background: Patient safety is a crucial issue worldwide, with medication errors particularly prescribing errors posing significant risks to clinical outcomes. Electronic Medical Records (EMR) have been widely implemented to minimize these errors. However, the scope and evolution of EMR’s impact on prescribing errors need a comprehensive analysis.Objective: This study systematically reviews the research landscape on the relationship between EMR implementation and prescribing errors using bibliometric analysis to identify key trends, research clusters, and future research opportunities.Methods: A qualitative bibliometric analysis was conducted on 117 articles published between 2020 and 2024, retrieved from the Scopus database. The PRISMA framework guided the screening process, including title, abstract, and full-text reviews based on predefined inclusion criteria. VOSviewer software was employed to visualize co-occurrence networks, overlay maps, and density distributions to identify dominant research themes.Results: Three primary cluster emerged: (1) technological innovations to detect and prevent prescribing errors in hospital environments; (2) integration of clinical practice with digital tools to improve healthcare quality; and (3) Optimization of EMR accuracy and clinical decision support systems to enhance efficiency and safety. Despite increasing research output, gaps persist regarding the long-term effects of EMR interventions, user acceptance, the synergy between technology and staff training, and interdisciplinary collaboration in EMR development.Conclusion: This bibliometric study synthesizes current knowledge and reveals critical research gaps. Strengthening user centered and interdisciplinary approaches is essential to further reduce prescribing errors and improve patient safety.
Renal Safety of Long-Term Antihypertensive Therapy: A Systematic Review Thendi Abdul Arief; Yohanna Lawanda da Costa; Niky Budiarti; Luthfiah Pertiwi; Agung Endro Nugroho; Zullies Ikawati
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 16, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.108256

Abstract

Background: Managing hypertension, a major risk factor for chronic kidney disease (CKD), requires long-term antihypertensive medication. However, clinical judgment and medication adherence are impacted by ongoing worries about its renal safety.Objectives: This study aimed to systematically evaluate and compare the renal safety profiles of antihypertensive drug classes during long-term use (>6 months) in hypertensive patients.Methods: Following the PRISMA 2020 principles, a systematic review was carried out. A thorough search of PubMed and ScienceDirect from 2015 to April 2025 was conducted ("ACEi OR ARB OR CCB OR Beta Blocker OR Diuretic AND Hypertension AND long-term use AND Renal Function"). A narrative synthesis was carried out in compliance with the Synthesis Without Meta-Analysis (SWiM) guideline due to clinical and methodological heterogeneity.Results: A total of 7214 studies were retrieved and reviewed. Only five papers were chosen after additional analysis. In comparison to CCBs in advanced chronic kidney disease (CKD), diuretics in combination with renin-angiotensin system inhibitors (RASi) were linked to a decreased incidence of significant adverse renal events (weighted HR 0.87, 95% CI 0.77-0.97). Despite a higher frequency of reversible eGFR drop and hyperkalemia, continuous ACEi/ARB treatment before dialysis initiation significantly decreased post-dialysis mortality (aHR 0.87, 95% CI 0.83-0.92). Compared to amlodipine, ACEi alone reduced eGFR and raised serum levels of potassium and creatinine for at least a year. In patients with resistant hypertension and baseline eGFR ≥30 mL/min/1.73 m², spironolactone successfully reduced blood pressure; however, initial elevations in serum creatinine and potassium needed to be monitored. Since blood pressure was well controlled, there was no discernible difference between ARBs and CCBs regarding the risk for end-stage kidney disease (HR 0.28; CI 0.14-0.58).Conclusion: Combining RASi with a diuretic provides superior renal protection for CKD patients compared to CCB. Post-dialysis mortality is also decreased by long-term ACEi/ARB usage. Under careful supervision, spirolactone is both safe and effective. Thus, regular use of ACEi/ARB and diuretic-RASi combination therapy is a safe and effective long-term method for maintaining renal function in hypertension.
Factors Associated with High-Alert Medication (HAM) Knowledge of Pharmaceutical Staff at Tangerang Regional Hospital, Indonesia Sherly Tandi Arrang; Devina Clara Alverina; Dion Notario
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 16, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.108378

Abstract

Background: High-alert medication (HAM) poses a high risk of causing serious harm to patients when used incorrectly. One of the critical strategies to reduce or prevent medication errors associated with medication is ensuring adequate knowledge among healthcare providers.Objectives: This study aims to assess knowledge level of pharmaceutical staff regarding HAM in hospital settings.Methods: An observational, non-experimental design was used with a cross-sectional approach. Data were collected with structured questionnaires and analyzed through multiple linear regression.Results: A total of 89 respondents participated in the study, of which 97% demonstrated a good understanding of HAM. The mean ± SD value of respondents was 87.97 ± 8.50, while the minimal, maximal, and median values were 64.71, 100, and 88.24, respectively. Multivariate analysis showed that variables such as age, gender, education level of pharmacy technicians, and work experience (p > 0.05) were not significantly associated with knowledge level. However, the education level of pharmacists indicated a statistically significant association (p < 0.05) with knowledge regarding HAM.Conclusion: This study found a significant association between the education level of pharmacist staff and knowledge level. Future studies should consider various hospital settings across Indonesia to gain a more comprehensive understanding regarding knowledge level of pharmaceutical staff concerning HAM. Additionally, further investigations are needed to explore the correlation between the incidence of medication errors associated with HAM and knowledge level of pharmaceutical staff.
Impact of Telepharmacy on Medication Adherence and Patient Satisfaction: A Literature Review Hannah Yusriyyah; Rano Kurnia Sinuraya; Auliya Abdurrohim Suwantika
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 16, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.108708

Abstract

Background: Technology has transformed patient care, with telepharmacy emerging as a major advancement. The use of telepharmacy expanded rapidly during and after the COVID-19 pandemic, ensuring continuity of medical care when in-person access was limited. It effectively addresses challenges such as social isolation, restricted facility visits, and the lack of face-to-face consultations. Clinical advantages include improved access to healthcare, reduced costs, higher patient satisfaction, enhanced counseling, and better therapy adherence.Objectives: This literature review aims to the impact of telepharmacy services on medication adherence and patient satisfaction across diverse healthcare settings and patient populations.Methods: A literature search was conducted in PubMed and Scopus using the Boolean operator AND and the keywords "telepharmacy," "adherence," and "satisfaction." The inclusion criteria comprised original articles, published in English between 2015-2025. A total of five articles met these criteria and were included in the review.Results: The reviewed studies consistently demonstrated the benefits of telepharmacy. Among HIV patients, medication adherence reached 100%, while adherence among outpatients with chronic illnesses was 95.2%. Patient satisfaction scores ranged from 9.4 to 9.8 out of 10, or 4.82 out of 5 on Likert scales. Patients particularly valued telepharmacy for its cost-effectiveness, convenience, improved understanding of medications, and continuity of care.Conclusion: Telepharmacy shows strong potential to enhance both patient satisfaction and medication adherence. However, further research is needed to address existing methodological limitations and to better understand its long-term impact and feasibility across various healthcare contexts.

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