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INDONESIA
Indonesian Journal of Rheumatology
Published by Indonesian Rheumatology Association
ISSN : 20861435     EISSN : 25811142     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Indonesian Journal of Rheumatology is a peer-reviewed open access journal on rheumatic diseases and connective tissue disorders. This is an official journal of Indonesian Rheumatology Associantion (IRA) and published twice a year since 2009. Our mission is to encourage the development of scientific and medical practice in rheumatic diseases and connective tissue disorders. This journal is self-focused on rheumatic disease and connective tissue disorders in the form of original article (extended and/or concise reports), review articles, editorial letters, leaders, lesson from memorable cases, book reviews, and matter arising. Both in clinical and laboratory including animal studies.
Arjuna Subject : -
Articles 8 Documents
 1 
Search results for , issue " Vol 3, No 1 (2011)" : 8 Documents clear
Diagnostic criteria of knee osteoarthritis in rheumatology outpatient clinic, Dr. Sardjito Hospital, Yogyakarta Kertia, Nyoman; Wachid, Deddy Nur; Krishnan, P N
Indonesian Journal of Rheumatology Vol 3, No 1 (2011)
Publisher : Indonesian Rheumatology Association

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Abstract

Background: Osteoarthritis (OA) is a chronic condition characterized by the breakdown of joints cartilage. Approximately 25% of persons 55 years of age or older have knee pain on most days and about half of them have radiographic OA in the knee. Prevalence of knee OA increases with age and it is more common in women than men. It is not easy to establish the diagnosis of knee OA since other knee disorders have similar clinicalsigns and symptoms.Objective: The purpose of this study was to observe the diagnosis pattern of knee OA in rheumatology outpatient clinic at Dr. Sardjito Hospital based on clinical and radiographic criteria of American College of Rheumatology (ACR). Method: The design of this study was cross-sectional. Data of the patients with knee OA were investigated from their medical records. Results: There were 212 subjects diagnosed with knee OA during the year 2000–2010. Most of the subjects (90.56%) were more than 50 years old. Women were more frequent affected by OA than men. All of the subjects (100%) had knee pain. Crepitus was found in98.11% subjects. Morning stiffness less than 30 minutes was found in 86.79% subjects. Osteophyte appearances were found in 79.72% subjects.Conclusion: Knee pain, crepitus, and age more than 50 years old were the most frequent criteria used to diagnose knee OA. Morning stiffness less than 30 minutes and osteophyte appearances were also frequent in knee OA.
Risk of cardiovascular disease in rheumatoid arthritis patients Utari, A P; Hidayat, Rudy; Setiyohadi, Bambang
Indonesian Journal of Rheumatology Vol 3, No 1 (2011)
Publisher : Indonesian Rheumatology Association

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Abstract

Despite rheumatoid arthritis (RA) therapy development has been in advance level today, its mortality remains increasing in general population. The mortality is mainly caused by early-manifested atherosclerosis and other cardiovascular complications. Available evidences showthis condition appears in early stage of the disease. Thus, early detection and management of cardiovascular risk, followed by control of these factors are necessaryto reduce morbidity and mortality of RA patients
Experience with cyclophosphamide in the treatment of a young woman with refractory dermatomyositis Setiyohadi, Bambang; Sinto, R
Indonesian Journal of Rheumatology Vol 3, No 1 (2011)
Publisher : Indonesian Rheumatology Association

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Abstract

Dermatomyositis is an idiopathic inflammatory myopathy characterized by the presence of rash and moderate-to-severe muscle weakness secondary to inflammation of the muscle. It can be a difficult condition to treat. Systemic corticosteroids are the first choice of treatment. However, about a quarter of patients either fail to respond to steroids or develop steroid-related toxicity. Second-line agents such as azathioprine and methotrexate are then added either alone, or in combination with corticosteroids. Failure of the disease to respond tosecond-line agents can then be a problem and this is often referred to as “refractory dermatomyositis”. Unfortunately, there is neither agreement nor wellestablished guidelines on the best regimen or combination of immunosuppressive agents in the case of refractory dermatomyositis.
Knee function measured by timed up-and-go test and stair-climbing test after isometric exercise of quadriceps femoris muscles in female patients with knee osteoarthritis Widjanantie, S C; Tulaar, A BM; Kasjmir, Yoga I; Prasetyo, S B
Indonesian Journal of Rheumatology Vol 3, No 1 (2011)
Publisher : Indonesian Rheumatology Association

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Abstract

Background: Osteoarthritis (OA), the most common form of joint disease, can result in long-term disability. Limitation of activity in OA patients may result in a decline in the strength of quadriceps femoris muscles and thus further reduce mobility. Isometric exercise has been known to increase muscle strength, decrease pain, and improve knee function.Objective: To evaluate knee function measured by timed up-and-go test (TUGT) and stair-climbing test (SCT) as well as muscle strength in the fourth and sixth week after isometric exercise of quadriceps femoris muscles and the correlation between these variables.Methods: Female patients with OA underwent isometric exercise of quadriceps femoris muscles 3 times a week for 6 weeks. Muscle strength (measured by tensiometer cable) and knee function (measured by TUGT and SCT) were evaluated before and at week 4and 6 of the exercise.Results: Thirty fi ve female patients were recruited in this study. The majority of the patients (45.7%) were between 60 to 65 years old. Obesity was found in 62.86% of the patients. At week 6, there was significant decrease in mean TUGT and SCT (by 39.0% and 45.6%, respectively; p<0.001), and signifi cant increase in mean right and left quadriceps muscles strength (by 47.9% and 36.7%, respectively; p<0.001). There was a weaknegative correlation (nonsignifi cant) of the increased strength of quadriceps muscles with the increase of knee function according to TUGT (right leg: r = -0.172, p = 0.323; left leg: -0.303, p = 0.077) and SCT (right leg: r = -0.031, p = 0.860); left leg: r = -0.058, p = 0.742).Conclusion: In female patients in this study, significant improvement was found in the strength of quadriceps muscles, TUGT, and SCT after 6 weeks of isometric exercise. There was no signifi cant correlation between muscle strength and knee function according to TUGT and SCT.
Sclerodermatomyositis Febyani, M; D, H Purbo; Hamijoyo, Laniyati; Sutedja, E; Suwarsa, O
Indonesian Journal of Rheumatology Vol 3, No 1 (2011)
Publisher : Indonesian Rheumatology Association

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Abstract

The classification of rheumatic diseases is still challenging due to several reasons. First, those diseases have several differential clinical features, which giving overlap symptoms. Second, the etiopathogenesis of those diseases remains elusive.Diagnosis of overlap syndrome is made when there are more than one well-defined connective tissue diseases in one patient, which may develop simultaneously or sequentially.1,2 The prevalence of overlap syndrome among autoimmune diseases is25%.2 The term sclerodermatomyositis or scleromyositisis is used to describe an overlap syndrome in patients with scleroderma and dermatomyositis/polymyositis (DM/PM).2,3,4 Sclerodermatomyositis usually affects adults, and it is rarely found in children.4 The clinical features of this syndrome are myalgia or myositis, arthralgia, scleroderma-like skin changes, Raynaud’s phenomenon (RP),2,3 interstitial lung disease, calcinosis,3 mask-like facies, dysphagia or esophageal dysmotility,4 as well as the presence of specific antibody Pm/Scl.2 Skin manifestations as the part of dermatomyositis include periorbital erythema and Gottron’s papules.3 We report this case due to its very rare occurrence. According to medical records in the Department of Dermatology as well as Rheumatology at Hasan Sadikin Hospital, Bandung, this is the first case recorded in the last 10 years.
Comparison of ultrasound therapy and local steroid injection in rotator cuff tendinitis Noviar, Noviar; Tulaar, A BM; Kasjmir, Y I; Sudarsono, S
Indonesian Journal of Rheumatology Vol 3, No 1 (2011)
Publisher : Indonesian Rheumatology Association

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Abstract

Objective: To evaluate the effectiveness of ultrasound therapy compared with local steroid injection for pain relief and movement limitation in rotator cuff tendinitis.Methods: Patients with rotator cuff tendinitis at the rheumatology and rehabilitation outpatient clinic at Cipto Mangunkusumo General Hospital were enrolled in a parallel randomized trial, in which each eligible patient were randomly assigned to one of two groups: one group received 10 sessions of ultrasound therapy given in 2 weeks, the other received a single dose of local steroid injection. Evaluation of the visual analog scale(VAS) was performed in 10 days (5 days for each week: day 1–5 and 8–12), while evaluation of the abduction as well as external and internal rotation range of motion(ROM) was performed twice a week (day 2, 5, 9, and 12). Change in the variables between the two groups at the end of the second week (day 12) was then compared. Results: Thirty patients, divided into two groups consisting of 15 patients each, were recruited in the study. Significant decrease in VAS during the followups was obtained in both groups, slightly earlier in the steroid injection group (day 2; p = 0.041) comparedwith the ultrasound group (day 3; p = 0.001). Significant increase in abduction ROM was achieved at the same rate (beginning at day 5) in both groups. Significant increase in internal rotation ROM was achieved at day 9 in the ultrasound group (p = 0.043) and day 12 in steroid injection group (p = 0.044). The increase in external rotation ROM in both groups was not found to be statistically signifi cant. At the end of the second week, signifi cant difference between the two groups was only shown in the abduction ROM, with higherincrease in the steroid group.Conclusions: Ultrasound therapy provided a comparable effectiveness to steroid injection inalleviating pain and improving ROM in patients with rotator cuff tendinitis.
Septic arthritis in malignancy Setiyohadi, Bambang; Santosa, D; Titis, Titis; Abdullah, A A
Indonesian Journal of Rheumatology Vol 3, No 1 (2011)
Publisher : Indonesian Rheumatology Association

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Abstract

Septic arthritis is an infection of a joint, which canbe caused by bacteria, viruses, fungi, or parasites. The infection may happen in distant sites of the body, which then spread hematogenously, or it could also result from open wounds, surgery, or unsterile injections.1 Septic arthritis is a serious condition that, if left undiagnosed and untreated, can cause joint destruction and an irreversible loss of joint function.2,3 Based on epidemiological data, the incidence of septic arthritis in general population is 2–10 cases in 100,000 people annually and is increased in those who have risk factors for septic arthritis, such as rheumatoid arthritis (RA) and joint prosthesis. In those with RA, the incidence of septic arthritis rises up to 30–70 cases in 100,000 people annually, and in those with prosthesis the figure is around 40–68 cases in 100,000 people annually.4,5 Septic arthritis can affect all age groups, but it is more prevalence in the elderly and in children under 5 years old, in which the prevalence is 8.4 and 5 cases, respectively, in 100,000 people annually.5 Septic arthritis is usually monoarticular, whereas polyarticular involvement occurs in only 10–15% of cases. The knee is involved in around 50% of cases.Septic arthritis is still a challenge for cliniciansince there has not been a significant decline in both morbidity and mortality in the last two decades.2 Late recognition and therapy can cause permanent joint dysfunction and even death; thus, early diagnosis and prompt therapy is expected to decrease the morbidity and mortality rate in septic arthritis.6 In this case report we would like to present a case of a woman suffering from septic arthritis with an underlying immunocompromised condition of malignancy
Comparison of the prevalence of hyperuricemia in families of patients with and without gouty arthritis among Balinese people Kambayana, Gede; Putra, T R
Indonesian Journal of Rheumatology Vol 3, No 1 (2011)
Publisher : Indonesian Rheumatology Association

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Abstract

Background: Gout is a metabolic disorder caused by hyperuricemia, which results from changes in uric acid metabolism. Both internal (e.g., genetics) and external factors (e.g., diet, habits, comorbidities) play role in the occurrence of hyperuricemia and the difference of hyperuricemia prevalence in different populations.Objective: To compare the prevalence of hyperuricemia in families of gout and non-gout patients among Balinese people.Methods: This cross-sectional study was carried out at the rheumatology clinic at Sanglah Hospital, Denpasar. Samples were collected using consecutive method and consisted of gout and non-gout patients. Several characteristics (alcohol and purine consumption,medications, blood pressure, body mass index, serum uric acid level, and serum creatinine) in both groups were collected and compared. Family members (fi rstdegree relatives) of patients in each group were also recruited and had their serum uric acid level measured and compared.Results: A total of 46 patients and 116 family members (23 patients and 58 family members in each group) were enrolled. Among gout patients, there was signifi cantlyhigher prevalence of hyperuricemia, serum uric acid level, blood pressure, and serum creatinine; and lower creatinine clearance compared with the non-gout patients. There was signifi cantly higher prevalence of hyperuricemia among families of gout patients comparedwith families of non-gout patients (60.3 vs. 29.3%, respectively; p = 0.001), with a prevalence ratio of 2.06. Mean serum uric acid level of the family members of gout patients were also signifi cantly higher than the family members of non-gout patients (7.24 (SD 1.74) vs. 5.92 (SD 1.63) mg/dL, respectively; p = 0.000).Conclusion: Among Balinese people in this study, significantly higher prevalence of hyperuricemia and mean serum uric acid level was observed in families of gout patients compared with families of non-gout patients.

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