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INDONESIA
Indonesian Journal of Rheumatology
Published by Indonesian Rheumatology Association
ISSN : 20861435     EISSN : 25811142     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Indonesian Journal of Rheumatology is a peer-reviewed open access journal on rheumatic diseases and connective tissue disorders. This is an official journal of Indonesian Rheumatology Associantion (IRA) and published twice a year since 2009. Our mission is to encourage the development of scientific and medical practice in rheumatic diseases and connective tissue disorders. This journal is self-focused on rheumatic disease and connective tissue disorders in the form of original article (extended and/or concise reports), review articles, editorial letters, leaders, lesson from memorable cases, book reviews, and matter arising. Both in clinical and laboratory including animal studies.
Arjuna Subject : -
Articles 302 Documents
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The Characteristics of Septic Arthritis Patients at Dr. Kariadi Hospital Semarang Malik, Zulfikar Alem Abdillah
Indonesian Journal of Rheumatology Vol. 17 No. 2 (2025): IJR VOL 17 No 2
Publisher : Indonesian Rheumatology Associantion

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Abstract

Background: Septic arthritis is an inflammatory disease caused by microbial infections such as bacteria, fungi, and viruses. Late diagnosis can lead to permanent joint damage, while overdiagnosis may result in unnecessary medical procedures. Although the incidence is relatively low, septic arthritis remains a medical concern due to its impact on joint function and patient quality of life. Determining the characteristics is needed to improve the diagnosis, treatment strategies, and prognosis of septic arthritis. Methods: This descriptive study utilized a retrospective design and was conducted on adult patients diagnosed with septic arthritis at dr. Kariadi General Hospital, Semarang, from January 2017 to August 2023. The analyzed variables included clinical manifestations, comorbidities, laboratory test results, synovial fluid analysis, synovial fluid culture, and antibiotic resistance. Results: Among the 49 patients, most were under 60 years old (67.4%) and male (61.2%). The knee joint was the most commonly affected site (87.8%) with the main symptoms such as joint pain, edema, and reduced range of motion (100%), along with inflammatory signs such as joint warmth (89.9%) and redness (83.7%). Synovial fluid analysis revealed that 53.06% of patients had cloudy and foul-smelling synovial fluid, with an average white blood cell count of 93,679.43/mm³ and a predominance of neutrophils (80.37%). Synovial fluid culture identified Staphylococcus aureus as the most common pathogen (34.7%), followed by Klebsiella pneumoniae (4.1%) and Salmonella sp. (2%). Antibiotic sensitivity tests showed Ampicillin/Sulbactam as the most effective treatment, while antibiotic resistance was observed in Gentamicin, Penicillin, and Linezolid. Conclusion: Staphylococcus aureus is the dominant pathogen, and rising antibiotic resistance remains a concern. Early diagnosis and targeted therapy are crucial for better patient outcomes.
Inflammatory Cascade in Aortic Wall: Latent Tuberculosis Complicating Takayasu Arteritis in a Young Bangladeshi Lady- The Silent Duo Gomes, Richmond Ronald
Indonesian Journal of Rheumatology Vol. 17 No. 2 (2025): IJR VOL 17 No 2
Publisher : Indonesian Rheumatology Associantion

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Abstract

Takayasu disease or pulseless disease is a rare chronic granulomatous panarteritis of unknown aetiology affecting large vessels, particularly the aorta and its main branches. It mainly affects females more than males with the ratio of 8:1 and in the second and third decade of life. Mechanism may be transmural fibrous thickening of the arterial walls. Takayasu arteritis is characterized by inflammation of the vessel wall, leading to occlusion of the vessel wall. It is represented with claudication, fever, and arthralgia. Clinical features are chest pain, vascular bruits, hypertension. There is indirect evidence signifying a potential link between tuberculosis (TB) and Takayasu’s arteritis (TAK); however, the exact mechanism and relationship between TAK and Mycobacterium tuberculosis (TB) remain elucidated. This case intends to highlight the association between latent TB and TAK, as early detection can avoid devastating consequences.

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