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INDONESIA
Jurnal Kesehatan Reproduksi
Published by Universitas Gadjah Mada
ISSN : 2302836X     EISSN : 2621461X     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Nursing Public Health
urnal Kesehatan Reproduksi is a scientific journal published by Association of Women and Children Reproductive Health Enthusiasts and Experts/Ikatan Pemerhati Anak dan Kesehatan Reproduksi/IPAKESPRO) who works closely with the Department of Obstetrics and Gynaecology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada. Jurnal Kesehatan Reproduksi first printed version was published in 2014 with ISSN 2302-836X. In 2016, we also have an online journal version with ISSN 2621-461X. Currently, we already use the Online Journal System, requiring all authors to submit their papers online. Afterwards, authors, editors and reviewers will be able to monitor the manuscript processing. This journal is published annually every April, August and December.
Arjuna Subject : -
Articles 5 Documents
 1 
Search results for , issue "special edition" : 5 Documents clear
Conference Abstract Book PIT HOGSI 2026 in Collaboration with Jurnal Kespro UGM PIT HOGSI 2026; Jurnal Kespro UGM
JURNAL KESEHATAN REPRODUKSI Special Edition : Conference Proceedings PIT HOGSI 2026
Publisher : Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jkr.119186

Abstract

Kegiatan Makalah Bebas pada Pekan Ilmiah Tahunan (PIT) HOGSI 2026 dengan tema “Implementasi Obstetri Ginekologi Sosial dalam Peningkatan Kuantitas & Kualitas Pelayanan Obstetri Ginekologi: Strategi Penurunan AKI, AKB serta Double Burden dengan Integrasi Kesehatan Reproduksi dan Hilirisasi Berbasis Kearifan Lokal”.
Hypokalemia Induced Arrhythmia during Pregnancy in Rural Area - A Case Report Dicky Ardian; Fajar Hamonangan Panjaitan; Fatima Zahra
JURNAL KESEHATAN REPRODUKSI Special Edition: Full Paper PIT HOGSI 2026
Publisher : Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jkr.119731

Abstract

Hyperemesis gravidarum is a severe form of nausea and vomiting during pregnancy that leads to persistent fluid and electrolyte imbalances, with hypokalemia being among the most clinically significant complications. Hypokalemia disrupts normal cardiac membrane excitability and can precipitate lethal arrhythmias, including ventricular tachycardia, ventricular fibrillation, and torsade de pointes — rhythms that carry a substantial risk of sudden cardiac death if not promptly identified and treated. These life-threatening arrhythmias arise from hypokalemia-induced hyperpolarization of the cardiomyocyte resting membrane potential, which paradoxically heightens ventricular automaticity and creates a vulnerable electrophysiological substrate susceptible to malignant dysrhythmias. A 33-year-old multiparous woman at 29 weeks of gestation presented to the emergency unit with a three-day history of generalized weakness, fatigue, persistent nausea, vomiting exceeding five episodes per day, diffuse muscle cramping, and abdominal discomfort. On examination, she was tachycardic with an irregular pulse of 100 beats per minute and tachypneic at 24 breaths per minute. The initial electrocardiogram demonstrated ventricular bigeminy, and brief self-terminating runs of non-sustained ventricular tachycardia were subsequently observed — findings that signaled an evolving arrhythmogenic state with potential for progression to fatal ventricular arrhythmia. Laboratory investigations confirmed severe hypokalemia with a serum potassium level of 1.7 mEq/L. Two-dimensional echocardiography revealed no structural cardiac abnormalities with a preserved left ventricular ejection fraction of 60%. The patient was managed with intravenous potassium chloride replacement, empirical magnesium sulfate supplementation, Bisoprolol, and Methyldopa in the Intensive Care Unit. Serial electrocardiograms documented progression from ventricular bigeminy to trigeminy before complete resolution following serum potassium normalization to 3.4 mEq/L. This case demonstrates that hypokalemia secondary to hyperemesis gravidarum can induce lethal ventricular arrhythmias, and that favorable outcomes are achievable through early recognition and systematic management.
Perbandingan Akurasi Rumus Johnson Toshach dengan Pemeriksaan Ultrasound untuk Prediksi Berat Badan Lahir Bayi Spontan Pervaginam Dicky Ardian; I Putu Satrya Wijaya
JURNAL KESEHATAN REPRODUKSI Special Edition: Full Paper PIT HOGSI 2026
Publisher : Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jkr.119740

Abstract

Latar Belakang: Estimasi berat janin yang akurat merupakan komponen penting dalam manajemen persalinan untuk menurunkan morbiditas dan mortalitas perinatal.Tujuan: Membandingkan akurasi rumus Johnson Toshach dengan pemeriksaan ultrasonografi dalam memprediksi berat badan lahir bayi spontan pervaginam.Metode: Penelitian cross-sectional dilakukan terhadap 99 ibu hamil yang melahirkan spontan pervaginam di Rumah Sakit Pupuk Kaltim Bontang periode Februari-April 2025. Data taksiran berat janin menggunakan rumus Johnson Toshach dan ultrasonografi dibandingkan dengan berat lahir aktual menggunakan uji Wilcoxon Signed-Rank Test. Akurasi dinilai dengan Mean Absolute Error (MAE) dan Mean Absolute Percentage Error (MAPE).Hasil: Ultrasonografi menunjukkan tidak ada perbedaan signifikan dengan berat lahir aktual (p=0,553) dengan selisih rata-rata 24,17 gram, sedangkan rumus Johnson Toshach menunjukkan perbedaan signifikan (p=0,000) dengan selisih 134,53 gram. Nilai MAE ultrasonografi (239,8 gram) lebih rendah dibanding Johnson Toshach (243,2 gram). Nilai MAPE keduanya kurang dari 10% (7,94% vs 7,83%).Kesimpulan: Ultrasonografi lebih akurat dibanding rumus Johnson Toshach dalam memprediksi berat lahir bayi, meskipun keduanya tergolong sangat akurat secara klinis.
Kehamilan dengan Penyakit Moyamoya Shila Rubianti Prawirodihardjo; Catherine Catherine; Leo Prawirodihardjo
JURNAL KESEHATAN REPRODUKSI Special Edition: Full Paper PIT HOGSI 2026
Publisher : Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jkr.119842

Abstract

Kehamilan pada pasien dengan penyakit serebrovaskular seperti penyakit moyamoya, merupakan kondisi berisiko tinggi yang memerlukan penatalaksanaan multidisiplin. Pasien wanita usia 36 tahun, G3P2A0, usia kehamilan 22 minggu, datang ke IGD dengan keluhan perut terasa kencang dan keram sejak subuh. Riwayat obstetri anak pertama lahir spontan tahun 2010 dan anak kedua dengan sectio caesarea tahun 2012. Pasien memiliki komorbiditas penyakit moyamoya dan telah menjalani operasi revaskularisasi pada Maret 2025. Pemeriksaan fisik dalam batas normal tanpa defisit neurologis. Pemeriksaan obstetri tinggi fundus sesuai usia kehamilan dan terdapat his. Ultrasonografi menunjukkan kehamilan tunggal intrauterin 22 minggu, janin hidup dengan denyut jantung 120 kali per menit, taksiran berat 500 gram, plasenta posterior, dan cairan ketuban cukup. Mempertimbangkan risiko maternal, dilakukan tindakan sectio caesarea disertai tubektomi bilateral. Bayi lahir dengan berat 500 gram dan meninggal 10 menit pascakelahiran. Kondisi ibu pascaoperasi stabil dan pemulihan berjalan baik. Kehamilan dengan penyakit moyamoya meningkatkan risiko komplikasi neurologis akibat perubahan tekanan darah selama kehamilan dan persalinan. Penelitian sebelumnya menunjukkan bahwa revaskularisasi sebelum atau selama kehamilan dapat menurunkan risiko kejadian serebrovaskular, meskipun tidak sepenuhnya menghilangkan risiko tersebut dan sectio caesarea sering dipilih untuk menghindari lonjakan tekanan intrakranial akibat mengejan. Pada kasus ini, riwayat revaskularisasi, usia maternal lanjut, kontraksi aktif usia 22 minggu, dan potensi risiko perdarahan serebral menjadi dasar pertimbangan terminasi operatif disertai sterilisasi definitif. Pada usia gestasi previabel dengan risiko maternal tinggi, keselamatan ibu menjadi prioritas utama dalam pengambilan keputusan klinis. Penatalaksanaan yang tepat dan pemantauan ketat pascaoperasi berperan penting dalam mencapai luaran maternal yang optimal.
Gold Nanoparticle Paper-Based Biosensor for Early Preeclampsia Screening Using Urinary hsa-miR-1-3p: A Systematic Review Mauliya Sri Sukmawati Wahyudi; Nidia Nursafitri; Endry Winarko
JURNAL KESEHATAN REPRODUKSI Special Edition: Full Paper PIT HOGSI 2026
Publisher : Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jkr.120209

Abstract

Preeclampsia remains a leading cause of maternal morbidity and mortality, particularly in low-resource settings where access to early screening tools is limited. Urinary miRNA-1-3p have emerged as promising biomarkers for preeclampsia due to their stability in maternal urine during the first trimester, weeks before the onset of clinical symptoms. It reflects early molecular and pathological changes in preeclampsia. Recent advances in nanotechnology have improved miRNA detection using electrochemical biosensors that are suitable for POC testing. The incorporation of gold nanoparticles, further enhances biosensor performance. This study aims to describe the potential of this novel biosensor for detecting miRNA-1-3p in maternal urine as an early antenatal screening tool for preeclampsia. There was elevated levels of miRNA 1-3p in maternal urine during first trimester in women with PE with p value 0.035, showing its potential as non-invasive biomarkers. This biosensor can detect miRNA 1-3p through probe hybridization and produces a measurable electrochemical signal. The incorporation of gold nanoparticles significantly enhances the biosensor sensitivity by about 80% by increasing electroactive surface area and enabling the detection of very low miRNA concentrations with low LOD by about 0.35 fM. Moreover, the gold nanoparticle enhance the biosensor specifity by reducing non-specific binding. This novel biosensor offers non-invasive, rapid, low cost, and portable tool, making it suitable for POC testing in low resource settings. This novel biosensor has strong potential to become a transformative as an early antenatal screening tool for preeclampsia in low-resource settings, may contribute to better maternal health outcomes. 

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