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ACI (Acta Cardiologia Indonesiana)
Published by Universitas Gadjah Mada
ISSN : 24605700     EISSN : 25794345     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ACI (Acta Cardiologia Indonesiana) is published twice a year (biannually) by the Department of Cardiology and Vascular Medicine Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Arjuna Subject : -
Articles 169 Documents
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Correlation between Small Dense Low Density Lipoprotein Level with Major Adverse Cardiac Event in Acute Coronary Syndrome Patients Maria Debby Maharatno; Hariadi Hariawan; Budi Yuli Setianto
ACI (Acta Cardiologia Indonesiana) Vol 2, No 1 (2016)
Publisher : Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/aci.17817

Abstract

Background: Cardiovascular disease is one of major problems in developed and developing countries. Atherosclerosis process begins with endothelial dysfunction. Lipoprotein is important factor in atherogenesis. Previous study stated that about 50% of cardiovascular events happened in individuals with normal or low LDL, therefore LDL plasma level alone is not enough to identifyindividuals with major adverse cardiac events. Individuals with small dense LDL predominant have 3 times fold to have cardiovascular risk. The goal of this study is to know whether the level of sdLDL has impact on in hospital major adverse cardiac events (MACE) of acute coronary syndrome patients. Methods: This was a cross sectional study, enrolling patients with acute coronary syndrome admitted and hospitalized in ICCU of Dr.Sardjito Hospital since September of 2013 until June 2015. The small dense LDL (sdLDLD) level was measured with previous formula using routine blood lipid component. Major adverse cardiac events (MACE) were determined upon observation during horpitalisation and defi ned as death, reinfarction, cardiogenic shock, acute heart failure, ventricular tachycardia or ventricular fi brillation, prolonged angina pain, and the need for immediate coronary intervention. Results: There were 159 patients with mean age 60.80 ± 9.8 years involved in this study. Onehundred eighteen (118) or 73% of patients were male. The mean of sdLDL level in patients with MACE was 108.34 ± 37.94 g/dl and mean sdLDL level in patients without MACE was 105.54 ± 43.10 g/dl. The level of sdLDL in patients without MACE was lower than patients with MACE (p=0.705). In this study we found the cut- off sdLDL level is ≥ 108.085 for higher sdLDL level and < 108.085 for lower sdLDL level. The higher sdLDL level have the prevalence ratio of 1.25 to develop MACE, however the value was not statistically signifi cant.Conclusion: The sdLDL level did not correlate with MACE in hospitalised patients with acute coronary syndrome.Keywords: small dense LDL, acute coronary syndrome, MACE
Dyslipidemia and Atherosclerosis B Setianto
ACI (Acta Cardiologia Indonesiana) Vol 3, No 1(S) (2017): Supplement, Abstracts of The 3rd InaPRevent 2017
Publisher : Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/aci.27252

Abstract

Dyslipidemia and atherosclerosis are met in the concept of atherogenic dyslipidemia that has .....
Acute Changes on Pulmonary Pressure Following Percutaneous Secundum Atrial Septal Defect Closure Wiryanto J., et al
ACI (Acta Cardiologia Indonesiana) Vol 3, No 2(S) (2017): Supplement, Abstracts of Jogja INternational CARdiovascular TOpic Series (JIN
Publisher : Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/aci.27974

Abstract

Acute Changes on Pulmonary Pressure Following Percutaneous Secundum Atrial Septal Defect Closure
Comparison of Predicted Significant Coronary Lesion by Duke Treadmill Score among Coronary Heart Disease Risk Factors in Patients with Positive Ischemic Response Treadmill Test David Rubiyaktho; Cholid Tri Tjahjono
ACI (Acta Cardiologia Indonesiana) Vol 4, No 1 (2018)
Publisher : Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/aci.36632

Abstract

Background: According to Framingham Study, independent risk factors for coronary heart disease (CHD) are diabetes, hypertension, smoking, dyslipidemia, family history of CHD and obesity. Previous study reported cut-off value of Duke Treadmill Score (DTS) < -0.5 represents a significant coronary lesion with positive predictive value 88.4%. Objective: To compare the incidence of predicted significant coronary lesions by DTS among various risk factors for coronary heart disease. Methods: A cross sectional study was done on 292 patients age 18 to 74 years old who had positive exercise testing for CAD screening during period of June 1st 2016 until May 30th 2017. DTS was calculated from treadmill test as: exercise time - (5 x ST deviation in mm) - (4 x exercise angina). A coronary lesion was predicted significant with DTS cut off value < -0.5. Results: Subjects mean age was 57 years old, male were 60.4%. The risk factors for CHD were found sequentially from the most frequent were hypertension 51.9%, smoking 35.3%, diabetes mellitus 23.1%, dyslipidemia 11.9%, obesity 4.2% and family history of CHD 6.3%. It was found that diabetes was significantly different from its effect on DTS value with p value = 0.021, while hypertension, obesity, dyslipidemia and family history CHD had no significant effect. Logistic regression found consistently that diabetes was significant (p=0.019). Conclusion: Predicted significant coronary lesions by DTS developed more frequent in diabetes compared to, hypertension, smoking, dyslipidemia, obesity and family history of coronary heart disease.
Efficacy of Lumbrokinase and Warfarin Compared to Single Warfarin on Thrombus Resolution in Deep Vein Thrombosis Anggia Endah Satuti; Hariadi Hariawan; Hasanah Mumpuni
ACI (Acta Cardiologia Indonesiana) Vol 1, No 2 (2015)
Publisher : Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/aci.17798

Abstract

Background: Deep vein thrombosis (DVT) is a challenging condition for clinician in all specialities. Prognosis after vein thromboembolism is worse and much worse after pulmonary embolism. Anticoagulant is the mainstay therapy for deep vein thrombosis, but there is still slow thrombus resolution even with the use of optimal anticoagulant. The use of intravenous thrombolytic agentsis one of the methods to signifi cantly lyse thrombus. Since there is increasing risk of bleeding with the use of the agents, indication is limited. Lumbrokinase is oral thrombolytic that may give significant thrombus lyses without increasing the risk of bleeding for deep vein thrombosis. This study was conducted to compare single warfarin therapy with combination of lumbrokinase andwarfarin for thrombus resolution in deep vein thrombosis patients. Methods: This study was a randomized open labeled trial comparing deep vein thrombosis patients using single warfarin therapy group to group using combination lumbrokinase and warfarin. 22 patients meet the inclusion and exclusion criteria. Patients were followed for 30 days and in the end of the trial, evaluation using vascular Doppler ultrasonography was done. Chi-square analysis was used to compare the outcome between two therapy groups. Results: In this trial, group therapy with added lumbrokinase to warfarin yielded a tendency toward better thrombus resolution compared to group with single warfarin therapy (58.3% vs.30%, p=0.231). Conclusion : Added therapy with lumbrokinase to warfarin may give better thrombus resolution as compared to single warfarin therapy, although there is no signifi cant difference between groups.Keywords: deep vein thrombosis, lumbrokinase, warfarin
The Real Landscape Of Pulmonary Artery Hypertension Associated With Congenital Heart Disease In Vietnam National Heart Institute – Bach Mai Hospital – Vietnam Thi Duyen Nguyen; Truong Thannh Huong
ACI (Acta Cardiologia Indonesiana) Vol 3, No 2(S) (2017): Supplement, Abstracts of Jogja INternational CARdiovascular TOpic Series (JIN
Publisher : Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/aci.27963

Abstract

The Real Landscape Of Pulmonary Artery Hypertension Associated With Congenital Heart Disease In Vietnam National Heart Institute – Bach Mai Hospital – Vietnam
Rehabilitation Program in a Patient Undergoing Mitral and Aortic Valve Replacement Surgery Purwati Pole Rio; Muhamad Taufik Ismail; Irsad Andi Arso
ACI (Acta Cardiologia Indonesiana) Vol 3, No 1 (2017)
Publisher : Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/aci.29759

Abstract

Heart disease due to valvular anomaly has increased prevalence along with increasing age. The operative management including reparation or substitution with prosthetic valve is the main therapy. Still becoming question mark either rehabilitation program is benefcience for patient undergoing valvular surgery. We report a patient with heart failure due to valvular heart disease and underwent double valve replacement surgery. Cardiac rehabilitation phase 1 and phase 2 was done. Patient feel physical condition is much better than before.  
Abnormal Heart Rate Recovery and Duke Treadmill Score as Predictor of Cardiovascular Mortality YB Utomo
ACI (Acta Cardiologia Indonesiana) Vol 3, No 1(S) (2017): Supplement, Abstracts of The 3rd InaPRevent 2017
Publisher : Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/aci.27266

Abstract

Background: The Duke Treadmill Score (DTS) has been well validated and widely used for .....
Atrial Arrythmia in Atrial Septal Defect Patient Paranita I., et al
ACI (Acta Cardiologia Indonesiana) Vol 3, No 2(S) (2017): Supplement, Abstracts of Jogja INternational CARdiovascular TOpic Series (JIN
Publisher : Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/aci.27991

Abstract

Atrial Arrythmia in Atrial Septal Defect Patient
Prediction of Failed Fibrinolytic Using Scoring System in ST Elevation Myocardial Infarction Patients Satria Mahendra; Budi Yuli Setianto; Hariadi Hariawan
ACI (Acta Cardiologia Indonesiana) Vol 2, No 2 (2016)
Publisher : Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/aci.22601

Abstract

Background: ST elevation myocardial infarction (STEMI) is the most common acute coronary syndrome in adults, and requiring immediate reperfusion. Primary percutaneous coronary intervention (PCI) is the main reperfusion therapy, but because of many limitations, fibrinolytic is often chosen. Fibrinolytic have high failure risk, so it is important to be able to predict whether this therapy will fail or not. This research aim to create a scoring system to predict failed fibrinolytic in STEMI patients. Methods: This is retrospective cohort study using medical records data from Dr. Sardjito General Hospital in Yogyakarta, recorded in June 2014-December 2015. The population was STEMI patients that reperfused with streptokinase regiment. Determination of failed fibrinolytic was using the difference in the ST segment elevation of the pre and post fibrinolytic electrocardiogram (ECG). The clinical variables of subjects were recorded. The statistical analysis was done and scoring system was constructed. Results: A total of 105 patients with mean age of 57.82±9.59 years were included in this study. Subjects with failed fibrinolytic was 53 patients (50.5%). Several variables were independently associated with failed fibrinolytis, i.e. the onset of ≥ 6 hours, hyperglycemia, and the location of anterior infarction (OR = 11.3, p = 0.000; OR = 6.11, p = 0.003 and OR = 10.5, p = 0.001, respectively). After scoring system was constructed, it was found that score ≥ 2 predict failed fibinolytic, with 53% sensitivity and 94% specificity. Conclusions : Scoring system consisting of onset ≥ 6 hours, hyperglycemia in arrival, and anterior infarct location, can be used to predict failed fibrinolytic in STEMI patients using streptokinase with 53% sensitivity and 94% specificity. Keywords: failed fibrinolytic scoring; fibrinolytic; STEMI; streptokinase

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