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INDONESIA
Jurnal Respirologi Indonesia
Published by Perhimpunan Dokter Paru Indonesia
ISSN : 08537704     EISSN : 26203162     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Jurnal Respirologi Indonesia (JRI) is an online and printed scientific publication of the Indonesian Society of Respirology (ISR). The journal is published thrice-monthly within a year (January, April, July and October). The journal is focused to present original article, article review, and case report in pulmonary and critical care medicine.
Arjuna Subject : -
Articles 12 Documents
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Search results for , issue "Vol 42, No 2 (2022)" : 12 Documents clear
Gastro-Esophageal Reflux Is Not a Common Cause of Chronic Cough; A Singapore Case Series Vijo Poulose
Jurnal Respirologi Indonesia Vol 42, No 2 (2022)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v42i2.300

Abstract

Background: Gastro-esophageal reflux disease (GERD) is believed to be a common cause of chronic cough.  There is a paucity of data on GERD-related cough (GERC) from Singapore. Our aim was to examine the prevalence, demographics and clinical features of GERC patients seen in a large teaching hospital in Singapore.Methods: We did a retrospective review of patients referred to the respiratory clinic for evaluation of chronic cough (≥ 6 weeks in duration). All patients diagnosed with GERC were further classified into 2 groups based on the likelihood of esophageal reflux being the cause of cough. 1) Likely GERC and 2) Possible GERC. We describe the demographics, clinical characteristics and the outcomes of these patients.Results: Of the 330 chronic cough patients seen over a 6 years period, 45 patients (13%) were diagnosed with GERC.  Most were women (69%), the median age was 53 years and the median duration of symptoms was 26 weeks. Fourteen patients were in the Likely group and 31 in the Possible group.  Throat symptoms or signs were found in 77 % of patients.Conclusions: Amongst patients referred for cough to a specialist clinic, GERD was not seen as a common cause.  Throat signs and symptoms were common and could add weight to the diagnosis of GERC. There was no particular timing for the cough with regards to day or night.
The Surfactant Protein D (SP-D) Serum Levels in Limestone Mining Worker Sita Laksmi Andarini; Anna Yusrika; Sri Wening Pamungkasningsih; Farhan Hilmi Taufikulhakim; Ahmad Hudoyo; Widhy Yudistira Nalapraya; Agus Dwi Susanto
Jurnal Respirologi Indonesia Vol 42, No 2 (2022)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v42i2.301

Abstract

Background: Limestone is sedimentation rocks consist of minerals calcite and aragonite, often contains silica, and fossils, commonly used in building materials. Limestone mining workers are at high risk to pneumoconiosis. Surfactant protein D(SP-D) is part of collectin family, and served as innate immune system of pathogen recognition receptor (PRR). SP-D level were usually increased in fibrotic lung disease. In this study, we sought the serum level of SP-D as marker for early pneumoconiosis in limestone worker in Indonesia.Method: This study was cross-sectional observational study. Participant of the study were 65 limestone workers, willing to participate in this study by signing informed consent, were questionnaire, and blood sample were collected to measure SP-D level by ELISA.Results: This study found that characteristic subjects dominated by male with the median of age was 42 years old and last education mostly elementary school. Majority duration of working <6 years and time working in a day >8 hours per day. The limestone mining workers mostly did not wear mask and had normal weight group. Majority limestone mining workers ever smoker, mean SP-D level in limestone workers was (66.3±5.5ng/mL), slightly higher than normal subject. Smoking status, gender, working hour were correlated with higher SP-D level.Conclusion: Although not statistically significant, the SP-D serum levels in limestone mining workers might be used as monitoring for early screening for pneumoconiosis in limestone workers.

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