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Jurnal Biomedika
Published by Universitas Setia Budi
ISSN : 20892136     EISSN : 23021306     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
JURNAL BIOMEDIKA (p-ISSN:1979-035X, e-ISSN: 2302-1306) is a scientific publication media that accommodates the scientific creativity of lecturers and researchers as outlined in scientific writing, both for academics in Setia Budi University and observers of medical biology and health. Articles published are the results of research in the field or in laboratories, scientific studies and studies of books that have never been published in other media. Information on scientific works can range from biotechnology, health, pharmacology, microbiology, biochemistry, and food analysis and health management.
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Articles 15 Documents
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Search results for , issue "Vol 12 No 2 (2019): Jurnal Biomedika" : 15 Documents clear
Uji Aktivitas Antijamur Ekstrak Etanol Daun dan Daging Buah Berenuk(Crescentia cujete, Linn.) terhadapCandida albicans ATCC 1023 Dewi Sulistyawati; Kartinah Wiryosoendjojo; Nony Puspawati
Biomedika Vol 12 No 2 (2019): Jurnal Biomedika
Publisher : Fakultas Ilmu Kesehatan Universitas Setia Budi Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (351.513 KB) | DOI: 10.31001/biomedika.v12i2.616

Abstract

Candida albicans is the cause of opportunistic candidiasis which is a fungal infection with the highest incidence. Candidiasis is a disease that can attack the oral cavity, mucous membranes, and genital areas. Indonesia is a country that is rich in biodiversity and people have used more than 6,000 species of plants as medicines and protection needs. One of the herbs that can be used as an alternative treatment for candidiasis is Calabash (Crescentia cujete, Linn.) Which has not been much studied. Throwing contains alkaloids, flavonoids, phenols and tannins which can damage the cell wall of Candida albicans. The purpose of this study was to determine the antifungal activity of leaves and fruit of Calabash (Crescentia cujete, Linn) against Candida albicans ATCC 1023 and determine the maximum concentration as an antifungal. This research is an experimental laboratory research. The test method used is the disk diffusion method. The extraction method used is ethanol maceration. The results showed that the leaves and fruit of Calabash had an antifungal activity against Candida albicans ATCC 1023. The maximum concentration of the extracts of the Calabash was 25% with inhibition zone diameters of 15 ± 0.8 mm and 9.33 ± 0, 57 mm.
Pemanfaatan Ekstrak dan Serbuk Kulit Jeruk Bali (Citrus Maxima Merr) untuk Mereduksi Kadar Krom(VI) dan Kadmium(II) pada Limbah Cair Artifisial Maria Fransiska Utami Bugis; Nur Hidayati; Dian Kresnadipayana
Biomedika Vol 12 No 2 (2019): Jurnal Biomedika
Publisher : Fakultas Ilmu Kesehatan Universitas Setia Budi Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (245.427 KB) | DOI: 10.31001/biomedika.v12i2.618

Abstract

Artificial waste is made using chrome K2Cr2O7 crystals, and cadmium from CdCl2 crystals. The purpose of this study was to determine the utilization of grapefruit skin extracts and powders in reducing the levels of chromium and cadmium. This research was carried out using artificial waste mixed with grapefruit peel extract and powder with a concentration of 0%, 0.5%, 1%, 1.5% and 2%. Metal content was measured using the Atomic Absorption Spectrophotometry method.The results of the research on chromium content before the treatment were 46.49 ppm and after the treatment using powder levels with a concentration of 0.5%; 1%; 1.5% and 2%, are namely 29.97 ppm, 33.20 ppm, 31.05 ppm, and 33.76 ppm, while the levels of extract are 40.43 ppm, 41.94 ppm, 42.34 ppm and 48 , 23 ppm. The results of the study of cadmium metal content before treatment were 102.36 ppm and after treatment using powder levels with variations in concentration of 0.5 %%; 1%; 1.5% and 2%, namely 33.61 ppm, 20.26 ppm, 13.44 ppm, and 16.82 ppm, while the extracts are 75.45 ppm, 74.86 ppm, 80.66 ppm and 85 , 10 ppm.
Pengaruh Penambahan Molase pada produksi Bioethanol dari Limbah Padat Industri Pati Aren Dewi Astuti Herawati; Andang Arif Wibawa
Biomedika Vol 12 No 2 (2019): Jurnal Biomedika
Publisher : Fakultas Ilmu Kesehatan Universitas Setia Budi Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (277.005 KB) | DOI: 10.31001/biomedika.v12i2.619

Abstract

Research has been carried out to determine the effect of the addition of molasses to on bioethanol production from palm starch industrial solid waste. The stages of this research were the preparation of raw materials, delignification of palm starch solid waste, lignin content analysis, enzyme production, anaerobic fermentation and ethanol content analysis. Delignification of palm starch solid waste using 3% NaOH solution. Enzyme production is produced from A. Niger and Trichoderma sp. Fermentation using 5 grams of delignified sample added a nutrient solution, a mixture of cellulase enzymes from A. niger and Trichoderma sp. by comparison (1: 2), molasses and Saccharomyces cereviseae. Analysis of ethanol levels was carried out every day until the 6th day. Delignification using 3% NaOH solution can reduce the level of lignin samples up to 17.15%. The addition of molasses containing 35% sugar as a source of sugar in the palm starch solid waste will increase the levels of bioethanol from 0.0904% to 3, 5407%, whereas molasses with 40% sugar content results in lower bioethanol levels. The higher the sugar content, the higher the level of bioethanol, but if the sugar content is too concentrated, it causes a slow fermentation process in the production of bioethanol.
Uji Aktivitas Larvasida Ekstrak Etanolik Daun Serai Wangi (Cymbopogon nardus L.) terhadap Larva Culex sp. Instar III Eka Cahya Nugraha; Tri Mulyowati; Rinda Binugraheni
Biomedika Vol 12 No 2 (2019): Jurnal Biomedika
Publisher : Fakultas Ilmu Kesehatan Universitas Setia Budi Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (265.513 KB) | DOI: 10.31001/biomedika.v12i2.620

Abstract

Culex sp. larvae is a vector of filariasis. The prevention effort is by controlling the presence of Culex sp. Citronella grass is known to contain secondary metabolite which is useful as plant-based insecticides. This research was conducted to determine the toxicity of the ethanolic extract of citronella grass on the mortality of Culex sp. III instar.The research method used was an experimental method with a completely randomized design (CRD) research design, the treatment that was tried was reagent control; negative control; 250 ppm; 353 ppm; 498 ppm; 702 ppm; 991 ppm; 1397 ppm; 1970 ppm, three replications for each treatment. Variables observed were larvae mortality in various concentrations. Larvae mortality was calculated after 24 hours. The data obtained were analyzed using the kruskal wallis test and the man whitney test with SPSS 21 application to determine the LC50value using probit analysis.The results indicate that the ethanolic extract of citronella grass functioned as larvasideonCulex sp. larvae III instar. The higher the concentration of citronella grass extract used, the greater the mortality percentage of Culex sp. larvae. III instar. The concentration of 991 ppm was the most effective concentration and the LC50value was 1036,54 ppm. The conclusion of this research is the ethanolic extract of citronella grass (Cymbopogonnardus L.) has larvicidal activity on Culex sp. larvae. III instar.
Pengaruh Pemberian Ekstrak Etanol Buah Sirsak (Annona muricata L.) Pada Kadar Kolesterol Low Density Lipoprotein (LDL) Tikus Putih (Rattus norvegicus) Hiperkolesterolemia Siti Fatimah; Desto Arisandi; Sismawati Sismawati
Biomedika Vol 12 No 2 (2019): Jurnal Biomedika
Publisher : Fakultas Ilmu Kesehatan Universitas Setia Budi Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (182.133 KB) | DOI: 10.31001/biomedika.v12i2.637

Abstract

The cause of Coronary heart disease is an increase caused due to increased cholesterol levels in the blood, so there is a risk of blockage in the blood vessels (atherosclerosis). LDL cholesterol which is abundant in the bloodstream will accumulate in the arteries and potentially cause blockages. Ethanol extract of soursop fruit (Annona Muricata L.) contains antioxidant compounds such as alkaloids, tannins, saponins, flavonoids and polyphenols that are needed to increase endurance and prevent various diseases that enter the body. Research has been conducted to determine the effect of soursop fruit ethanol extract (Annona Muricata L.) on Low Density Lipoprotein (LDL) cholesterol levels white Rat (Rattus Norvegicus) hipercolesterolemia. This research was conducted experimentally with 10 male white rats (Rattus Novergicus, L.), aged 2-3 months with a weight of 150-200 g, which were divided into 2 groups: the control group and the treatment group. Hypercholesterolemia induction is done by giving high fat diet foods for 7 days. Soursop fruit ethanol extract was given in a sonde to the treatment group at a dose of 3.6 mg / 200gBB / day for 14 days and measurements of LDL cholesterol levels were carried out on days 16 and 30 by the CHOD-PAP examination method. Data were analyzed by Paired t-test. The results showed LDL cholesterol levels in the treatment group showed that as many as 5 mice decreased, the mean decreased by 32.49 mg / dl while in the control group as many as 2 mice decreased, the mean decreased by 0.76 mg / dl. There was a significant difference (p <0.05) in changes in LDL cholesterol levels in the treatment group. Soursop fruit etanol extract with 3.6 mg / 200gBB / day for 14 days can reduce LDL cholesterol levels in hypercholesterolemia rats.

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