cover
Contact Name
Defrizal, S.Kom.M.Kom
Contact Email
-
Phone
+6275139246
Journal Mail Official
redaksi_jurnalobgin@fk.unand.ac.id
Editorial Address
RSUP DR. M. Djamil Padang, Jl. Perintis Kemerdekaan Padang, Sumatera Barat 25127
Location
Kota padang,
Sumatera barat
INDONESIA
Andalas obstetrics and gynecology journal
Published by Universitas Andalas
ISSN : 25798324     EISSN : 25798413     DOI : https://doi.org/10.25077/aogj
Core Subject : Health, Science,
Andalas Obstetrics And Gynecology Journal (AOJ) (e-ISSN: 2579-8324) is a peer-reviewed, open-access national journal published by Universitas Andalas and is dedicated to publish and disseminate research articles, literature reviews, and case reports, in the field of obstetrics, gynecology, and other related disciplines.
Articles 13 Documents
Search results for , issue "Vol 6, No 1 (2022)" : 13 Documents clear
Factors Related to the Success of IVF Program in Morula BMC Clinic Padang Nurmala Sari Dewi; Dedy Hendri; Hafni Bachtiar
Andalas Obstetrics And Gynecology Journal Vol 6, No 1 (2022)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.1.50-57.2022

Abstract

Introduction: Infertility is the failure of a couple to get pregnant 12 months after having regular sex without contraception. One in seven couples even have to be treated using Assisted Reproductive Technology (TRB). The most widely used TRB is In Vitro Fertilization (IVF). In general, the success rate is in the range of 40-50%. In Indonesia, there are 32 clinics providing IVF program with a success rate of 30-40%. The success rate of IVF is influenced by multi variables that affect directly or indirectly including age, Antral Follicle Count (AFC), Anti Mullerian Hormone (AMH), basal Follicle Stimulating Hormone (FSH), number of egg cells, egg quality, sperm quality, embryo quality, and endometrial thickness. Objectives: This study aims to determine the factors associated with the success of IVF programMethods: This study used a cross-sectional analytic study design which was conducted on 77 medical records of patients undergoing IVF program at Morula Clinic BMC Padang from January 2018-December 2020. All data were then analyzed using univariate, bivariate and multivariate analysis with appropriate statistical test; Results: The average age of the study subjects was (33.4 ± 3.93) years, the average length of infertility was (6.73 ± 3.69) years, the most used antagonist protocols (88.16%), with the most common causes of infertility being factors sperm (48.9%) and overweight BMI (36.4%). From the bivariate analysis, it was found that the factors related to the number of eggs were age (r = -0.349), AFC (r = 0.471), FSH (p 0.02), and AMH (p < 0.01) with the dominant factor being AMH. Egg quality was related to AFC (p 0.007) and FSH (p 0.002), with the dominant factor being AFC. Embryo quality correlated with egg quality (p < 0.01). Meanwhile, the success of implantation was dominantly related to the embryo quality factor (0.034); Conclusion: The most dominant factor to the success of IVF program is the quality of the embryo.Keywords: IVF, IVF success
DIFFERENCES IN PROTEASE ACTIVATED RECEPTOR-1 AND THROMBINE LEVELS IN PREECLAMPSIA AND NORMAL PREGNANCY Gistin Khusnul Khatimah; Joserizal Serudji; Vaulinne Basyir
Andalas Obstetrics And Gynecology Journal Vol 6, No 1 (2022)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.1.27-34.2022

Abstract

Introduction: Preeclampsia is a condition caused by alterations in endothelial function during pregnancy. Changes in endothelial function result in an increase in coagulation and microvascular fibrin accumulation, which results in impaired placental perfusion. Thrombin, which converts fibrin to fibrinogen, as well as platelet activity, the fibrinolytic system, and anticoagulants, are all procoagulant circumstances in preeclampsia. Thrombin contributes to the pathogenesis of preeclampsia by increasing the expression of sFlt-1 thereby providing an antiangiogenic response. Protease Activated Receptor-1 (PAR-1) is a mediator of thrombin for coagulation and inflammation in preeclampsia. Inhibition of Protease Activated Receptor-1 expression in trophoblasts can enhance placental angiogenesis and vascular remodeling. Recently, only few studies have assessed the levels of Protease Activated Receptor -7 and thrombin in preeclampsia.Objective: To determine the difference in levels of Protease Activated Receptor-1 and thrombin in preeclampsia and normal pregnancyMethods: This study is observational with a cross-sectional comparative study design. Sampling was conducted from March 2020 to March 2021. A total of 66 patients were investigated, with 33 samples of preeclampsia and 33 samples of normal pregnancy. The independent sample T-test was used for statistical analysis.Results: The mean levels of Protease Activated Receptor-1 in the preeclampsia group were higher at 28.56 ± 7.68 ng/mL while normal pregnancy was 21.67 ± 6.92 ng/mL. The results of statistical tests showed that there was a significant difference in levels of Protease Activated Receptor-1 between the preeclampsia and normal pregnancy groups (p<0.05). The mean thrombin level in the preeclampsia group was higher at 72.23 ± 7.99 ng/mL, while in normal pregnancy it was 63.70 ± 8.92 ng/mL. The difference in thrombin levels between the preeclampsia and normal pregnancy groups was statistically significant (p<0.05).Conclusion: Preeclampsia was associated with greater levels of Protease Activated Receptor-1 and thrombin than normal pregnancy. There was a significant difference in the mean levels of Protease Activated Receptor-1 and thrombin between preeclampsia and normal pregnancy.Keywords: Thrombin, Protease Activated Receptor-1(PAR-1), Preeclampsia
Analysis of the stress level of resident physician education program specialist in Obstetrics and Gynecology Andalas University in 2020 Ari Fuad Fajri; Bobby Indra Utama; Hardisman Hardisman
Andalas Obstetrics And Gynecology Journal Vol 6, No 1 (2022)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.1.65-71.2022

Abstract

Introduction:The Specialist Doctor Education Program (PPDS) is one of the academic education of general practitioners and is known as a resident doctor to become a specialist and is at the forefront ofhealth services. Resident doctors are expected to be flexible clinicians, educators, researchers, andadministrators by the end of their residency training. It often requires stressful hard work, and is oftenreported as a cause of burnout, anxiety, depression, anger, irritability, anxiety, sleep deprivation,fatigue, substance abuse, and psychosocial problems. One of the problems that often occurs with residents is long working hours. Based on the working hours regulation adopted in the UK since 1998, namely the European Working Time Directive (EWTD) and a policy change in 2007 and 2009 called The New Deal, the working hours of resident doctors to achieve optimal performance is 56 hours per week. In the initial survey of 10 PPDS Obgin Unand residents, network station residents still had to carry out their duties 24 hours a day for 1 month in the hospital. Except for applying for certain permits. If you add up, the average working hours in 1 week is more than 60 working hours. Objective: This study aims to determine the stress level of resident doctors in the Education Program of  Obstetric and Gynecology Specialist, Andalas University in 2020Methods: This research is a quantitative study followed by qualitative method using an explanatory design. Data was taken using the triangulation method. The data was taken from questionnaires, Focus Group Discussion (FGD), and document review from Obstetric and Gynecology residents of all semester at Andalas University.Results: The highest stress level in the Obstetric and Gynecology residents of Andalas University in 2020 was 60.3% at moderate level, there was a relationship between stress levels with graduation and semester. The highest stress domain is ARS (Academic Related Stressor) and SRS (Social Related Stressor).Conclusion: the stress level in the Obstetric and Gynecology residents of Andalas University in 2020 is at a moderate level, and the highest stress domain is ARS (Academic Related Stressor) and SRS (Social Related Stressor).Keywords: Resident Doctor; Obstetric and Gynecology; stress

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