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Hygroma Colli Vaulinne Basyir; Try Genta Utama
Andalas Obstetrics And Gynecology Journal Vol 5, No 2 (2021)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.5.2.262-268.2021

Abstract

Background : Hygroma coli is a malformation of the lymphatic system in the form of a membrane cyst filled with fluid, limited by the epithelium that is located in the anterolateral or occipito-cervical region. The prenatal diagnosis of cystic hygroma coli by ultrasound is based on an apparently bilateral, mostly symmetrical, and sometimes unilateral cystic structure located in the occipitocervical region. Large hygroma coli can cause pressure on the respiratory tract and digestion, so it requires management as soon as possible.The main treatment modality is surgical excision to remove the cystic lesion. The prognosis of a hygroma coli cyst depends on its size and the action taken because it is rare for cases to experience spontaneous regression.Destination : Reported a case of hygroma colliMethods : Case ReportCase Report : Case 24 years old women with preterm G1P0A0L0 26-27 weeks + Hygroma colli + IUFD + Suspected COVID-19. On ultrasound examination, it was found that BPD =4,71; AC = 15,91; FL = 2,89; EFW = 330 gr; FHR = (-); Cyst = 5,06 x 3,26. The presence of head presentation, IUFD, hygroma colli was found. The patient was planned for labor induction and the progress of labor was followed. Patient provided inform consent that baby was death during pregnancy and need to be labored. The baby was born, weight 300 gr, body length 14 cm and A/S 0/0. Postmortem physical examination revealed findings of hygroma colli infants such membrane cyst filled with fluid that located in the occipito-cervical region. Conclusion: Hygroma colli is a malformation of the lymphatic system and the prognosis or complications depends on the size of cyst. Careful prenatal examination is required in diagnosis and termination of pregnancyKeywords: Hygroma Colli, prenatal diagnosis
Thanatophoric Dysplasia Vaulinne Basyir; Yusrawati Yusrawati; Gistin Husnul Khatimah
Andalas Obstetrics And Gynecology Journal Vol 5, No 1 (2021)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.5.1.112-118.2021

Abstract

Background: The term tanatophorik comes from the Greek word thanatophorus which means "innate death" or "bearing death". The problem that underlies this disease is the process of bone formation. This disease is associated with an autosomal dominant inherited mutation of the fibroblast growth factor 3 receptor (FGFR3) gene on the arm of chromosome 4 (4p16.3). Because FGFR3 is the main modulator in bone formation, the typical clinical features of this disease include shortening of the extremities, curved femur, clover-like skull and narrowing of the thoracic cavity.Tanatophoric dysplasia is a skeletal disorder that is "lethal" or deadly. The deaths occurred due to respiratory failure caused by reduced chest cavity capacity, hypoplastic lungs and / or brainstem compression.Destination: Reported a case of thanatophoric dysplasiaMethod: Case Report Case Report: Case 33 years old woman, with preterm parturient G1P0A0H0 35-36 weeks 1 latent phase + history of 2x laparotomy + suspected fetal tanatophoric dysplasia. On ultrasound examination, it was found that BPD = 9.14 cm; AC = 30.56 cm; HC = 32.05 cm; FL = 2.55 cm; AFI; 9.06cm; SDAU = 1.72 cm. The presence of frontal bosing, saddle nose and micromilia (proximal, distal, phalanges) was found. The patient was planned for vaginal delivery and the progress of labor was followed. Patients provided informed consent regarding the possibility of fetal death during labor and after birth. During the active phase of the labor process, hypotony uterine innersia occurs and oxytocin drip is performed to accelerate labor. The baby was born male, weight 2175 grams, body length 34 cm and A / S: 1/0. Postmortem physical examination revealed macroscopic findings of tanatophoric dysplasia infants such as hypertelorism, low nasal bridge, cranio-facial disproportion. Narrow chest with protruding abdomen and short, bent limbs.Conclusion: Tanatophoric dysplasia is "lethal" skeletal dysplasia. Careful prenatal examination is required in diagnosis and termination of pregnancy. Keywords: Thanatophoric dysplasia, prenatal diagnosis
DIFFERENCES IN PROTEASE ACTIVATED RECEPTOR-1 AND THROMBINE LEVELS IN PREECLAMPSIA AND NORMAL PREGNANCY Gistin Khusnul Khatimah; Joserizal Serudji; Vaulinne Basyir
Andalas Obstetrics And Gynecology Journal Vol 6, No 1 (2022)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.1.27-34.2022

Abstract

Introduction: Preeclampsia is a condition caused by alterations in endothelial function during pregnancy. Changes in endothelial function result in an increase in coagulation and microvascular fibrin accumulation, which results in impaired placental perfusion. Thrombin, which converts fibrin to fibrinogen, as well as platelet activity, the fibrinolytic system, and anticoagulants, are all procoagulant circumstances in preeclampsia. Thrombin contributes to the pathogenesis of preeclampsia by increasing the expression of sFlt-1 thereby providing an antiangiogenic response. Protease Activated Receptor-1 (PAR-1) is a mediator of thrombin for coagulation and inflammation in preeclampsia. Inhibition of Protease Activated Receptor-1 expression in trophoblasts can enhance placental angiogenesis and vascular remodeling. Recently, only few studies have assessed the levels of Protease Activated Receptor -7 and thrombin in preeclampsia.Objective: To determine the difference in levels of Protease Activated Receptor-1 and thrombin in preeclampsia and normal pregnancyMethods: This study is observational with a cross-sectional comparative study design. Sampling was conducted from March 2020 to March 2021. A total of 66 patients were investigated, with 33 samples of preeclampsia and 33 samples of normal pregnancy. The independent sample T-test was used for statistical analysis.Results: The mean levels of Protease Activated Receptor-1 in the preeclampsia group were higher at 28.56 ± 7.68 ng/mL while normal pregnancy was 21.67 ± 6.92 ng/mL. The results of statistical tests showed that there was a significant difference in levels of Protease Activated Receptor-1 between the preeclampsia and normal pregnancy groups (p<0.05). The mean thrombin level in the preeclampsia group was higher at 72.23 ± 7.99 ng/mL, while in normal pregnancy it was 63.70 ± 8.92 ng/mL. The difference in thrombin levels between the preeclampsia and normal pregnancy groups was statistically significant (p<0.05).Conclusion: Preeclampsia was associated with greater levels of Protease Activated Receptor-1 and thrombin than normal pregnancy. There was a significant difference in the mean levels of Protease Activated Receptor-1 and thrombin between preeclampsia and normal pregnancy.Keywords: Thrombin, Protease Activated Receptor-1(PAR-1), Preeclampsia
Pengaruh Likopen terhadap Kadar Soluble FMS-Like Tyrosine Kinase 1 pada Preeklamsi Vaulinne Basyir; Prima Nanda Fauziah; Akhmad Yogi Pramatirta; Yanwirasti Yanwirasti; Johanes C. Mose; Fadil Oenzil
Jurnal Kesehatan Andalas Vol 9, No 4 (2020): Online December 2020
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v9i4.1513

Abstract

Preeklamsi merupakan penyebab utama morbiditas dan mortalitas baik maternal maupun perinatal. Tujuan: Menganalisis pengaruh pemberian likopen terhadap kadar sFlt-1 secara in vitro pada sel trofoblas model preeklamsi. Metode: Penelitian ini dilakukan secara eksperimental di Laboratorium Genetika Molekuler dan Kultur Sel Fakultas Kedokteran Universitas Padjadjaran selama periode 2017-2018. Sampel serum diperoleh dari RS. Dr. Hasan Sadikin Bandung, sesuai kriteria inklusi dan eksklusi. Kriteria inklusi adalah pasien yang telah didiagnosis preeklamsi berdasarkan pemeriksaan tekanan darah dan protein urin, dan kriteria eksklusi adalag pasien yang tidak datang kontrol atau tidak bisa dihubungi. Penelitian ini terdiri dari dua tahap, pertama ditentukan nilai LD50 likopen terhadap sel trofoblas kemudian dijadikan dasar nilai konsentrasi yang akan digunakan, selanjutnya dilakukan pemeriksaan sFlt-1 menggunakan metode Elisa pada kultur sel trofoblas kondisi normal dan preeklamsi dengan analisa data menggunakan analisis varians (Anova) dan uji Duncan untuk mengetahui perbedaan antar variabel. Hasil: Nilai LD50 adalah 250 ug/ml dan serial konsentrasi yang digunakan mulai dari 1,953 sampai dengan 125 ug/ml. Didapatkan kadar sFlt-1 menurun secara signifikan (p0,05) dari 39,5445 menjadi 31,1342 pg/ml pada sel trofoblas yang diinduksi dengan serum preeklamsi setelah pemberian konsentrasi likopen sebesar 15,625-31,25 ug/ml yang nilainya mendekati keadaan pada sel trofoblas yang diinduksi serum kehamilan normal. Pemberian likopen dapat menurunkan kadar sFlt-1 pada sel trofoblas preeklamsi. Simpulan: Likopen dapat merubah kadar sFlt-1 dan perubahannya dipengaruhi oleh konsentrasi dan jenis serum.Kata kunci: likopen, preeklampsi, sFlt-1 
Hubungan Kunjungan Posyandu Terintegrasi PAUD dengan Status Gizi dan Kemampuan Berbahasa pada Anak Balita Usia 4-5 Tahun di Wilayah Kerja Puskesmas PAUH Kota Padang Tahun 2019 Satra Yunola; Hafni Bachtiar; Vaulinne Basyir
Jurnal Kesehatan Andalas Vol 8, No 4 (2019): Online December 2019
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v8i4.1136

Abstract

AbstrakPosyandu terintegrasi Pendidikan Anak Usia Dini (PAUD) merupakan penyelenggaraan integrasi layanan sosial dasar di posyandu, salah satunya adalah pembinaan gizi dan kesehatan ibu anak serta pos PAUD. Posyandu yang melaksanakan program pengembangan tambahan, meliputi perkembangan kognitif, bahasa, fisik, sosial dan emosional anak yang dapat dipantau salah satunya pada integrasi Posyandu PAUD, namun pelaksanaannya belum maksimal. Tujuan: Menentukan hubungan kunjungan posyandu terintegrasi PAUD dengan status gizi dan kemampuan berbahasa pada anak balita usia 4-5 tahun. Metode: Desain penelitian yaitu crossectional terhadap 73 responden. Pengumpulan data dilakukan dengan melakukan observasi langsung pada anak menggunakan lembar pedoman perkembangan bahasa anak di Posyandu terintegrasi PAUD pada bulan Maret sampai September 2019 dengan metode simple random sampling menggunakan uji Chi-square. Hasil: Analisis kuantitatif menunjukkan bahwa lebih dari separoh kunjungan posyandu terintegrasi PAUD tidak aktif (60,2%), sebagian besar status gizi lebih (68,5%), lebih dari separoh kemampuan berbahasa anak kurang baik (60,2%). Hasil uji Chi-Square menunjukkan terdapat hubungan kunjungan posyandu terintegrasi PAUD dengan status gizi (ρ<0,05) dan kemampuan berbahasa (ρ<0,05) anak balita usia 4-5 tahun. Simpulan: Kunjungan posyandu terintegrasi PAUD penting dihadiri oleh ibu untuk memantau status gizi dan kemampuan berbahasa anak. 
PEMBERDAYAAN MASYARAKAT DI NAGARI LUMPO KABUPATEN PESISIR SELATAN Yusrawati Yusrawati; Yulizawati Yulizawati; Lusiana El Sinta Bustami; Aldina Ayunda Insani; Vaulinne Basyir; Hudila Rifa Karmila; Feni Andriani; Erda Mutiara Halida; Fitrayeni Fitrayeni; Uliy Iffah; Miranie Safaringga; Laila Rahmi; Rafika Oktova; Ulfa Farah Lisa; Muhammad Iqbal; Rahmat Syawqi; Syandrez Prima Putra; Liganda Endo Mahata; Elfira Yusri
BULETIN ILMIAH NAGARI MEMBANGUN Vol 2 No 4 (2019)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (451.712 KB) | DOI: 10.25077/bina.v2i4.130

Abstract

Pesisir Selatan Regency is one of the districts with 15 sub-districts with the largest population in IV Jurai District. The number of deaths per year on the South Coast fluctuates. In 2015 the number of infant deaths increased from 6 to 42 people (male 29 and 13 female) from the previous year, AKABA of 47 from 18 in the previous year. There were 16 toddlers with herniated nutrition and many pregnant women, namely around 273 pregnant women. Based on a preliminary study conducted by the activity implementation team at the Lumpo Public Health Center, IV Jurai District, Pesisir Selatan Regency, it is known that there is no ultrasound examination facility in pregnancy and prenatal yoga facilities at the Lumpo Puskesmas, besides that there are no similar activities carried out at SD Negeri 016 and MTsN. Nagari Lumpo which is included in the work area of Lumpo Puskesmas. Several tests can be done during pregnancy as an effort to detect early and prevent complications and growth disorders in the fetus. Among others, by monitoring weight gain during pregnancy, conducting general examinations (vital signs), physical examinations that focus on the breasts, abdomen, genitalia with inspection, palpation, auscultation, and percussion, ultrasonography (USG) examinations, and performing supporting examinations in the form of laboratory examination (hemoglobin examination). The result of this activity is an increase in each target group's quality of life by the stages of life after this activity.
Correlation Ofmaternal Serum Ferritin With Cord Blood Dopamine Concentration Wulan Dewi Rizky; Vaulinne Basyir; Rima Semiarty
Journal of Midwifery Vol 3, No 2 (2018): Published on December 2018
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (288.901 KB) | DOI: 10.25077/jom.3.2.53-64.2018

Abstract

Anemia in pregnancy is a common health problems today, where iron deficiency is the main cause. Iron deficiency will affect the various organs and metabolic pathways, especially the central dopamine pathway. Dopamine is a neurotransmitter that is found in brain and affects human interpersonal actions and correlations. The purpose of this study was to determine the correlation of maternal serum feritin with cord blood dopamine concentration. The design of this study was cross sectional, observe 30 pregnant women with their babies born in Rika Hardi, SSiTmaternity clinic. Samples were selected by consecutive sampling. Ferritin and dopamine concentration was checked at BalaiLaboratoriumKesehatan West Sumatera, where ferritin concentration by ECLIA and dopamine concentration by ELISA. Data were analyzed with Spearman correlation test to find the correlation of maternal serum feritin with cord blood dopamine concentration. The study results obtained, mean concentration of maternal serum ferritin 33,21±26,08 ng/mL and cord blood dopamine concentration 172,27±27,21 ng/L. Correlation test of maternal serum feritin with cord blood dopamine concentration had p value = 0,301 (p>0,05). In this study, we can conclude that there is no correlation between maternal serum feritin with cord blood dopamine concentration.Further research is needed by considering various factors that affect maternal ferritin concentration such as food intake and iron supplementation, and which affect dopamine concentration, such as stress and adequate sleep.
Antenatal Ultrasound Should Be For All; Congenital Diaphragmatic Hernia - A Case Report Reyhan Julio Azwan; Vaulinne Basyir; Yusrawati yusrawati
Journal of Midwifery Vol 6, No 2 (2021): Published on Desember 2021
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jom.6.2.69-74.2021

Abstract

Congenital diaphragmatic hernia is an anatomical defect of the diaphragm, which allows protrusion of abdominal viscera into the chest, causing serious pulmonary and cardiac complications in the neonate. In this study we aimed to present a case of congenital diaphragmatic hernia. We investigated a 35-36 weeks of pregnancy, with a pregnancy carried out in a public hospital in Padang, West Sumatera. We suggest that if diagnosis occurs in the prenatal period, the prognosis of this disease improves.
The relationship between the level of knowledge and attitudes with the behavior of pregnant women in recognizing the danger signs of pregnancy in the city of Padang in 2021 Deden Kurniawan; Ferdinal Ferry; vaulinne Basyir
Andalas Obstetrics And Gynecology Journal Vol. 6 No. 2 (2022)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.2.159-166.2022

Abstract

Introduction: Lack of knowledge of mothers in recognizing danger signs during pregnancy is one of the factors for the high maternal mortality rate. This study aims to determine the relationship between the level of knowledge and attitudes with the behavior of pregnant women in recognizing the danger signs of pregnancy in the city of Padang. Methods: This research using a cross sectional approach to 56 pregnant women at 3 Public Health Centers in Padang City from January 2022 to April 2022. To determine that relation, the chi-square test was used with 95% CI (α 0.05). Results: The results shows that most of the respondents who use the KIA book have a good knowledge (83%), have a positive attitude (89.3%) and behave appropriately (89.3%) and there is also a relationship between the level of knowledge and behavior. KIA book users in recognizing the danger signs of pregnancy (P = 0.04) and the relationship between attitudes and behavior of pregnant women using KIA books in recognizing pregnancy danger signs (p = 0.001). The relationship between knowledge and attitudes with the behavior of KIA book users in recognizing the danger signs of pregnancy(p-value0.001versus0.846). Conclusion: There is a relation between the level of knowledge and the behavior of KIA book users in recognizing the danger signs of pregnancy, between attitudes and the behavior of pregnant women using KIA books in recognizing the danger signs of pregnancy and attitudes have a more dominant influence than knowledge.
Relationship Of Maternal Nutrition Status And Mother's Height Of Stunting Events In Tolls At Puskesmas Pagambiran Annisa Namirah Nasution; Vaulinne Basyir; Rinang Mariko; Nur Afrainin Syah; Yusri Diannne Jurnalis; Hudila Rifa Karmia
Contagion: Scientific Periodical Journal of Public Health and Coastal Health Vol 5, No 1 (2023): CONTAGION
Publisher : Universitas Islam Negeri Sumatera Utara, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30829/contagion.v5i1.14973

Abstract

Abstract Stunting is a chronic malnutrition problem characterized by height for age which is <-2 SD according to the median standard of child growth. Stunting causes poor quality of human resources, which will reduce productivity. The factor causing the problem of stunting In Tools AtPagambiran Health Center, Padang City is the lack of clean water sanitation. The purpose of this study was to determine the relationship between the nutritional status of the mother, the height of the mother, and the mother's knowledge of the incidence of stunting in toddlers at the Pagambiran Health Center, Padang City.This research is an observational analytic study with a cross-sectional design. This research was conducted at the Pagambiran Health Center in Padang City with 3457 populations in November 2021-December 2022. The research sample was 174 mothers and children aged 24-59 months. Sampling using Stratified Random Sampling and Simple Random Sampling. Data collection used a questionnaire and the MCH handbook. The statistical tests used are Chi-square and Logistic Regression.The results of the univariate study found that 55 mothers (31.6%) had a history of chronic energy deficiency, and 12 mothers (6.9%) had a height < 150 cm. The results of the bivariate study using chi-square analysis obtained the p-value of each variable, namely the mother's nutritional status (p=0.005) and mother's height (p=0.018). The study concludes that there is a relationship between the mother's nutritional status and the mother's height in the incidence of stunting in toddlers at the Pagambiran Health Center, Padang City. Researchers suggest that counseling related to stunting can be carried out for pregnant women and prospective brides as an initial preventive measure. Keywords: Chronic Energy Deficiency, Mother's Height, Stunting.