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Science Midwifery
Published by Institute of Computer Science
ISSN : 20867689     EISSN : 27219453     DOI : -
Core Subject : Health,
Dentistry Health Professions Nursing Public Health Veterinary
Jurnal Kebidanan dan ilmu kesehatan ini adalah di terbitkan 2 kali dalam setahun, dalam bidang kebidanan dan perawat.
Arjuna Subject : Keperawatan - Maternity and Midwifery
Articles 1,494 Documents
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Hybrid mediator panel: A legal pluralism framework for resolving medical disputes under the Indonesian health law Repelita Witri; Melita Widyastuti; Nanang Zuli Purwanto; Marsudi Dedi Putra; Carolina Kuntardjo
Science Midwifery Vol 14 No 1 (2026): Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v14i1.2319

Abstract

Background The transformation of medical-legal relationships from a paternalistic to a contractual model in Indonesia has triggered complex disputes that conventional, legalistic mechanisms often fail to resolve fairly. While Law No. 17 of 2023 mandates non-litigation resolution, the current mediation framework remains trapped in a state-centric paradigm that marginalizes professional ethics and social norms. Research Gap A critical research gap exists in the prevailing legal monism approach, which creates a "justice gap" by failing to synchronize the disciplinary reviews of Article 308 with criminal judicial processes, thereby leaving healthcare workers vulnerable to criminalization and patients without substantive restoration. Method This study employs a normative-prescriptive research method with a qualitative-synthetic conceptual development design to reconstruct the mediation function. Findings The findings introduce a "Hybrid Mediator Panel" and a "Multi-Layered Screening" mechanism as a functional reconfiguration of Article 310 of Law No. 17 of 2023. This model integrates state law, professional ethics (deontological), and living law (deliberation) into a single convergent system to ensure that settlement agreements are not only legally enforceable but also sociologically valid. Contribution This study provides a strategic blueprint for the Indonesian government to implement restorative justice in health law, ensuring legal certainty for medical professionals while simultaneously achieving holistic justice and therapeutic recovery for patients.
Nanophytosome delivery system and in vivo test of combination of binahong leaf extract (Andredera cordifolia) and bay leaf (Syzygium polyanthum) as a diabetic wound healer Arip Saifurrohman; Garnadi Jafar; Entris Sutrisno; Fathurahman Ari Senjaya
Science Midwifery Vol 14 No 1 (2026): Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v14i1.2326

Abstract

This study aimed to develop and characterize a nanophytosome system containing combined extracts of bay leaf (Syzygium polyanthum) and binahong leaf (Anredera cordifolia), and to evaluate its wound healing activity through in vivo study. The extracts were prepared by maceration using 96% ethanol and characterized through phytochemical screening and LC-MS/MS analysis. Nanophytosomes were formulated using phospholipid complexes with variations of surfactants, followed by homogenization and sonication. The formulations were evaluated for particle size, polydispersity index, zeta potential, and entrapment efficiency. The results showed that particle size ranged from 16.30 to 927.18 nm, with the smallest size observed in Tween 80-based formulation. The polydispersity index ranged from 0.20 to 0.86, indicating better homogeneity in Tween 80 systems. Zeta potential values ​​were in the range of −6 to −17 mV, suggesting moderate stability. Entrapment efficiency was high in all formulations (92.5–97.3%), with the highest value observed in Cremophor-based formulation. In vivo evaluation demonstrated that the nanophytosome significantly accelerated wound healing compared to control groups, as indicated by faster wound contraction and improved tissue regeneration. In conclusion, the nanophytosome system enhanced the physicochemical properties and delivery of bioactive compounds, showing potential as an effective therapeutic approach for wound healing.
219-13FR Sacha inchi oil-based nanoemulsion of bay leaf (syzygium polyanthum) and binahong leaf (anredera cordifolia) extracts and in vitro release using a dialysis membrane Dudy Agustian Hidayat; Garnadi Jafar; Winasih Rachmawati; Rieztya Aliza; Sulthan Abdul Basith Ratmoko
Science Midwifery Vol 14 No 1 (2026): Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v14i1.2327

Abstract

This study aimed to develop and characterize a nanoemulsion system containing combined extracts of bay leaf (Syzygium polyanthum) and binahong leaf (Anredera cordifolia) using sacha inchi oil, and to evaluate its in vitro release profile using a dialysis membrane method. The extracts were prepared by maceration using 96% ethanol and characterized through physicochemical and phytochemical analyses. Nanoemulsions were formulated using Cremophor RH40 and PEG 400, followed by homogenization and sonication. The formulations were evaluated for particle size, polydispersity index (PDI), zeta potential, and morphology. The results showed that the optimized formulation (NEC5) exhibited the smallest particle size (130.06 ± 56.66 nm), acceptable PDI (0.45 ± 0.12), and moderate zeta potential (−14.15 ± 4.88 mV), indicating good stability. Morphological analysis confirmed spherical and uniformly distributed droplets. In vitro release studies demonstrated an initial burst release followed by a more controlled release pattern, with the nanoemulsion showing more stable release compared to the extract. In conclusion, the nanoemulsion system successfully improved the physicochemical properties and controlled release behavior of the plant extracts, indicating its potential as an effective delivery system for plant-derived bioactive compounds.
Formulation and characterization of nanoparticles combination of binahong leaves and bay leaves as a thin oral herbal preparation for diabetes prevention Eka Priana; Garnadi Jafar; R. Herni Kusriani; Intan Meilani; Ranti Fitriani
Science Midwifery Vol 14 No 1 (2026): Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v14i1.2328

Abstract

Diabetes mellitus is a chronic metabolic disease with a steadily increasing prevalence globally. Binahong leaves (Anrederacordifolia) and bay leaves (Syzygiumpolyanthum) contains flavonoids, such as kaempferol, which have the potential as antidiabetics, but its use is limited by the low solubility, stability, and bioavailability of the active compounds. This study aims to formulate and characterize a nanoparticle herbal medicine combining the two leaves using PlantCrystal technology, and develop it into an oral thin herbal preparation. The simplicia was processed through sorting, washing, drying, grinding, and sieving, then characterized and screened for phytochemicals. The nanoparticle herbal medicine was evaluated based on particle size, polydispersity index, zeta potential, and particle morphology. The membrane lysis release test showed an increase in the release of active substances compared to the simplicia. Furthermore, the formulation was developed into an oral thin herbal and evaluated for its physical properties, including organoleptic, water content, pH, film thickness, fold resistance, weight uniformity, and disintegration time.

Page 150 of 150 | Total Record : 1494

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