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INDONESIA
Science Midwifery
ISSN : 20867689     EISSN : 27219453     DOI : -
Core Subject : Health,
Jurnal Kebidanan dan ilmu kesehatan ini adalah di terbitkan 2 kali dalam setahun, dalam bidang kebidanan dan perawat.
Articles 1,520 Documents
Hybrid mediator panel: A legal pluralism framework for resolving medical disputes under the Indonesian health law Witri, Repelita; Widyastuti, Melita; Purwanto, Nanang Zuli; Putra, Marsudi Dedi; Kuntardjo, Carolina
Science Midwifery Vol 14 No 1 (2026): April: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v14i1.2319

Abstract

Background The transformation of medical-legal relationships from a paternalistic to a contractual model in Indonesia has triggered complex disputes that conventional, legalistic mechanisms often fail to resolve fairly. While Law No. 17 of 2023 mandates non-litigation resolution, the current mediation framework remains trapped in a state-centric paradigm that marginalizes professional ethics and social norms. Research Gap A critical research gap exists in the prevailing legal monism approach, which creates a "justice gap" by failing to synchronize the disciplinary reviews of Article 308 with criminal judicial processes, thereby leaving healthcare workers vulnerable to criminalization and patients without substantive restoration. Method This study employs a normative-prescriptive research method with a qualitative-synthetic conceptual development design to reconstruct the mediation function. Findings The findings introduce a "Hybrid Mediator Panel" and a "Multi-Layered Screening" mechanism as a functional reconfiguration of Article 310 of Law No. 17 of 2023. This model integrates state law, professional ethics (deontological), and living law (deliberation) into a single convergent system to ensure that settlement agreements are not only legally enforceable but also sociologically valid. Contribution This study provides a strategic blueprint for the Indonesian government to implement restorative justice in health law, ensuring legal certainty for medical professionals while simultaneously achieving holistic justice and therapeutic recovery for patients.
Nanophytosome delivery system and in vivo test of combination of binahong leaf extract (Andredera cordifolia) and bay leaf (Syzygium polyanthum) as a diabetic wound healer Saifurrohman, Arip; Jafar, Garnadi; Sutrisno, Entris; Senjaya, Fathurahman Ari
Science Midwifery Vol 14 No 1 (2026): April: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v14i1.2326

Abstract

This study aimed to develop and characterize a nanophytosome system containing combined extracts of bay leaf (Syzygium polyanthum) and binahong leaf (Anredera cordifolia), and to evaluate its wound healing activity through in vivo study. The extracts were prepared by maceration using 96% ethanol and characterized through phytochemical screening and LC-MS/MS analysis. Nanophytosomes were formulated using phospholipid complexes with variations of surfactants, followed by homogenization and sonication. The formulations were evaluated for particle size, polydispersity index, zeta potential, and entrapment efficiency. The results showed that particle size ranged from 16.30 to 927.18 nm, with the smallest size observed in Tween 80-based formulation. The polydispersity index ranged from 0.20 to 0.86, indicating better homogeneity in Tween 80 systems. Zeta potential values ​​were in the range of −6 to −17 mV, suggesting moderate stability. Entrapment efficiency was high in all formulations (92.5–97.3%), with the highest value observed in Cremophor-based formulation. In vivo evaluation demonstrated that the nanophytosome significantly accelerated wound healing compared to control groups, as indicated by faster wound contraction and improved tissue regeneration. In conclusion, the nanophytosome system enhanced the physicochemical properties and delivery of bioactive compounds, showing potential as an effective therapeutic approach for wound healing.
219-13FR Sacha inchi oil-based nanoemulsion of bay leaf (syzygium polyanthum) and binahong leaf (anredera cordifolia) extracts and in vitro release using a dialysis membrane Hidayat, Dudy Agustian; Jafar, Garnadi; Rachmawati, Winasih; Aliza, Rieztya; Ratmoko, Sulthan Abdul Basith
Science Midwifery Vol 14 No 1 (2026): April: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v14i1.2327

Abstract

This study aimed to develop and characterize a nanoemulsion system containing combined extracts of bay leaf (Syzygium polyanthum) and binahong leaf (Anredera cordifolia) using sacha inchi oil, and to evaluate its in vitro release profile using a dialysis membrane method. The extracts were prepared by maceration using 96% ethanol and characterized through physicochemical and phytochemical analyses. Nanoemulsions were formulated using Cremophor RH40 and PEG 400, followed by homogenization and sonication. The formulations were evaluated for particle size, polydispersity index (PDI), zeta potential, and morphology. The results showed that the optimized formulation (NEC5) exhibited the smallest particle size (130.06 ± 56.66 nm), acceptable PDI (0.45 ± 0.12), and moderate zeta potential (−14.15 ± 4.88 mV), indicating good stability. Morphological analysis confirmed spherical and uniformly distributed droplets. In vitro release studies demonstrated an initial burst release followed by a more controlled release pattern, with the nanoemulsion showing more stable release compared to the extract. In conclusion, the nanoemulsion system successfully improved the physicochemical properties and controlled release behavior of the plant extracts, indicating its potential as an effective delivery system for plant-derived bioactive compounds.
Formulation and characterization of nanoparticles combination of binahong leaves and bay leaves as a thin oral herbal preparation for diabetes prevention Priana, Eka; Jafar, Garnadi; Kusriani, R. Herni; Meilani, Intan; Fitriani, Ranti
Science Midwifery Vol 14 No 1 (2026): April: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v14i1.2328

Abstract

Diabetes mellitus is a chronic metabolic disease with a steadily increasing prevalence globally. Binahong leaves (Anrederacordifolia) and bay leaves (Syzygiumpolyanthum) contains flavonoids, such as kaempferol, which have the potential as antidiabetics, but its use is limited by the low solubility, stability, and bioavailability of the active compounds. This study aims to formulate and characterize a nanoparticle herbal medicine combining the two leaves using PlantCrystal technology, and develop it into an oral thin herbal preparation. The simplicia was processed through sorting, washing, drying, grinding, and sieving, then characterized and screened for phytochemicals. The nanoparticle herbal medicine was evaluated based on particle size, polydispersity index, zeta potential, and particle morphology. The membrane lysis release test showed an increase in the release of active substances compared to the simplicia. Furthermore, the formulation was developed into an oral thin herbal and evaluated for its physical properties, including organoleptic, water content, pH, film thickness, fold resistance, weight uniformity, and disintegration time.
Design of an IVA test mannequin model as a learning media for midwifery students at the Tasikmalaya Health Polytechnic, ministry of health Mulyani, Nunung; Kurnia, Herni; Suptiani, Laila Putri
Science Midwifery Vol 14 No 1 (2026): April: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v14i1.2193

Abstract

Introduction: Cervical cancer remains one of the leading causes of cancer-related deaths among women in Indonesia, particularly in developing countries. The Visual Inspection with Acetic Acid (IVA Test) is a simple, affordable, and sensitive method recommended by the World Health Organization (WHO) for early detection. However, many healthcare workers, including midwives, still lack sufficient skills in performing the test. This study aims to develop a prototype of an IVA Test manikin as an innovative learning medium to enhance midwifery students’ competencies. Methods: This research employed the Research and Development (R&D) approach through stages including anatomical graphic design of the cervix, prototype fabrication using medical-grade silicone, and simulation of acetic acid application using hypochlorite acid. The cervical part was designed modularly with litmus paper that turns white when applied with hypochlorite, mimicking a positive IVA reaction. Validation and consultation were conducted with material and media experts to assess design accuracy and functionality. A small-scale trial was carried out involving 10 midwifery students from Poltekkes Kemenkes Tasikmalaya. Results: The prototype successfully resembled the realistic shape, color, and texture of the cervix. Expert validation indicated that the manikin met anatomical and functional criteria, while student trials demonstrated that the model was easy to use, improved understanding of procedural steps, and increased confidence in performing the IVA Test. Conclusion: The developed IVA Test manikin serves as an effective, practical, and sustainable learning innovation to enhance midwifery students’ clinical skills in cervical cancer early detection. Further studies with larger samples and expert validation are recommended to optimize its educational model/video.
Association of maternal dietary patterns, stress levels, and physical activity during pregnancy with stunting among children under five in brebes regency Herwianti, Chyntia Olyvia Rizki; Handayani, Oktia Woro Kasmini; Indarjo, Sofwan
Science Midwifery Vol 14 No 1 (2026): April: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v14i1.2245

Abstract

Stunting remains a major public health nutrition problem in Indonesia, particularly in Brebes Regency, which has one of the highest stunting prevalences in Central Java Province. Stunting can originate during the prenatal period and is influenced by maternal lifestyle factors during pregnancy. This study aimed to analyze the relationship between maternal lifestyle during pregnancy—including dietary patterns, physical activity, and stress levels—and the incidence of stunting among children aged 24–59 months in Brebes Regency. A case–control study design was employed involving 144 respondents (72 mothers of stunted children and 72 mothers of non-stunted children) selected from several public health centers. Data were collected through structured interviews using validated questionnaires and analyzed using bivariate analysis and logistic regression. The results showed that maternal dietary patterns, stress levels, and physical activity during pregnancy were significantly associated with stunting incidence. Mothers with unbalanced dietary patterns had a higher risk of having stunted children (OR = 2.87; p = 0.002). Similarly, moderate–high maternal stress (OR = 2.54; p = 0.004) and inappropriate physical activity (OR = 2.39; p = 0.006) were significantly associated with increased odds of stunting. Maternal lifestyle during pregnancy plays a crucial role in determining child growth outcomes. Therefore, stunting prevention strategies should prioritize prenatal interventions through improved nutritional education, stress management, and promotion of safe physical activity for pregnant women.
Dioscorea alata enhances on the corpus luteum histology in an endometriosis mouse model Makiyah, Sri Nabawiyati Nurul; Rahmawati, Suci Nur
Science Midwifery Vol 14 No 1 (2026): April: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v14i1.2301

Abstract

Endometriosis is a chronic inflammatory disease that causes ovarian damage and infertility. Dioscorea alata contains anti-inflammatory and antioxidant agents. This study examined the effect of ethanol extract of Dioscorea alata (EEDA) on the histology of corpus luteum in an endometriosis mouse model. This research is a quasi-experimental with a post-test-only controlled group design. Twenty-four mice were divided into six groups: control (C), negative control (NC) induced endometriosis model, positive control (PC) induced endometriosis model and letrozole, and three treatment groups induced endometriosis model and EEDA 50, 250, and 500 mg/kg body weight (T1, T2, T3). The number and diameter of corpus luteum analyzed with Kruskal-Wallis test, One-way ANOVA, and Duncan's test. The number of corpus luteum decreased in negative control group and increased significantly in the treatment groups (P = 0.038). The diameter of corpus luteum decreased in the negative control group and increased non-significantly in the treatment groups (P = 0.206). The conclusions of this research prove that EEDA has a positive effect both the number and diameter of corpus luteum in an endometriosis mouse model.
Legal pluralism in the practice of informed consent among indigenous communities Hardini, RA. Sri; Respati, Agustinus Giri; Roeswandi, RM. Achmad; Ropii, Imam
Science Midwifery Vol 14 No 1 (2026): April: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v14i1.2321

Abstract

The transformation of individual autonomy standards in modern health law often creates a conflict of norms when implemented within the communal social structures of indigenous peoples. This research aims to analyze the dialectics of legal pluralism in the practice of medical informed consent to find a middle ground between centralistic state regulations and the "living law" within indigenous communities. This study employs an empirical legal research method with a socio-legal approach using a descriptive-qualitative design. The results reveal the phenomenon of "collective autonomy," where the validity of medical consent does not merely rely on individual will but is significantly determined by the legitimacy of customary authority and family deliberation mechanisms. Findings indicate that current informed consent practices tend to be legalistic-formal and fail to translate medical risks into local cultural logic, thereby creating judicial vulnerability for both medical personnel and indigenous patients. It is concluded that a reconstruction of the informed consent model based on "Integrative Legal Pluralism" is required, which accommodates communal consent and the use of cultural mediators as a legitimate part of medico-legal procedures. This model offers a strategic solution to achieve a more inclusive healthcare service, respecting the constitutional rights of indigenous peoples while ensuring equitable legal certainty in Indonesia.
SDS-PAGE characterization of dialyzed protein fractions from mycobacterium tuberculosis isolates for tuberculosis biomarker screening Barokah, Githa Agripina; Novitriani, Korry; Hasanah, Annisa Nur; Ferdiani, Dina; Setyoningrum, Fransisca Probo
Science Midwifery Vol 14 No 1 (2026): April: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v14i1.2333

Abstract

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis, in which the identification of protein profiles serves as an important approach in diagnostic research and specific antigen development. This study aimed to analyze the protein profile of dialyzed fractions from Mycobacterium tuberculosis isolates using the SDS-PAGE (Sodium Dodecyl Sulfate–Polyacrylamide Gel Electrophoresis) method. Protein isolation was carried out through sonication at 4 °C to lyse the cells and release intracellular proteins without causing denaturation. The resulting lysate supernatant was subjected to 30% ammonium sulfate precipitation to separate proteins based on their solubility, followed by dialysis to remove residual salts and unwanted small molecules. The total protein concentration was measured using a photometer with a total protein reagent, showing a relatively low value, indicating that the protein fraction was concentrated on specific molecules with higher purity. The SDS-PAGE analysis revealed the presence of a protein band with an estimated molecular weight of 77,6 kDa, suggesting the successful purification of protein fractions based on molecular weight. Based on these findings, it can be concluded that the combination of sonication, ammonium sulfate precipitation, and dialysis is effective as a preliminary purification method to obtain purer proteins from Mycobacterium tuberculosis isolates and enables more specific characterization of protein profiles through SDS-PAGE.
Relationship between stunting status and parental parenting patterns with the incidence of dental caries in toddlers in the working area of the bugel public health center Dessylindra, Herningrum; Fauziah, Munaya; Purnamawati, Dewi; Dihartawan, Dihartawan
Science Midwifery Vol 14 No 1 (2026): April: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v14i1.2334

Abstract

Stunting and dental caries are two common child health problems that often occur simultaneously and influence each other. Parental care patterns, education level, knowledge, and socioeconomic status play important roles in dental caries occurrence in stunted children. To analyze the relationship between stunting status and parental care patterns with dental caries occurrence in children under five, as well as the factors underlying dental caries. Cross-sectional study on 162 children under five (81 stunted and 81 normal) at Bugel Public Health Center. Data collected through questionnaires and examinations. Analysis used Chi-Square test and multiple logistic regression (α=0.05). Prevalence of stunting and caries were each 90.1%. Significant relationships found between stunting and caries (p=0.001; OR=17.25), parental care and caries (p=0.002; OR=18.61), education and caries (p=0.035; OR=4.42), knowledge and caries (p=0.047; OR=4.30). Socioeconomic status was not significantly associated (p=0.433). Multivariate analysis showed stunting (OR=5.59; p=0.032) and parental care (OR=4.80; p=0.040) as significant factors. Stunting status and parental care are significant factors of dental caries in children under five. Integrated intervention programs are needed to address stunting and dental health, parenting education, and routine monitoring.

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