cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Ristiawan Muji Laksono
Contact Email
anestpain@ub.ac.id
Phone
+6281336172271
Journal Mail Official
anestpain@ub.ac.id
Editorial Address
Anesthesiology and Intensive Therapy Program, Medicine FacultyBrawijaya University, Malang Indonesia Jl. Jaksa Agung Suprapto no.2, Malang, Indonesia
Location
Kota malang,
Jawa timur
INDONESIA
Journal of Anaesthesia and Pain
Published by Universitas Brawijaya
ISSN : 27223167     EISSN : 27223205     DOI : http://dx.doi.org/10.21776/ub.jap
Core Subject : Health,
Health Professions Medicine & Pharmacology
Journal of Anaesthesia and Pain is a peer-reviewed and open-access journal that focuses on anesthesia and pain. Journal of Anaesthesia and Pain, published by Anesthesiology and Intensive Therapy Specialist Program of Medicine Faculty, Brawijaya University. This journal publishes original articles, case reports, and reviews. The Journal s mission is to offer the latest scientific information on anesthesiology and pain management by providing a forum for clinical researchers, scientists, clinicians, and other health professionals. This journal publishes three times a year. Subjects suitable for the Journal of Anaesthesia and Pain are all subjects related to anesthesiology and pain management.
Arjuna Subject : Kedokteran - Anesthesiology and Pain Medicine
Articles 1 Documents
 1 
Search results for , issue "Vol. 4 No. 1 (2023): January" : 1 Documents clear
Continuous Ketamine Administration Decreases Monocyte Count in Sepsis Patients in Intensive Care Units Hartono, Ruddi; Jaya, Wiwi; Mayasari, Mayasari; Isngadi, Isngadi
Journal of Anaesthesia and Pain Vol. 4 No. 1 (2023): January
Publisher : Faculty of Medicine, Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jap.2023.004.01.01

Abstract

Background: Cytokines storm becomes the most common cause of mortality in sepsis patients treated in the intensive care unit (ICU). Cytokines storm is characterized by an excessive elevation in the immunocompetent cells, including monocyte. Ketamine, as a sedating agent, has immunosuppressive properties. This study was conducted to determine the effect of ketamine on monocyte count in septic patients in the ICU.Methods: This is a quantitative case-control  study of 30 patients treated in the ICU. The study subjects were divided into control (n=15) and treatment (n=15) groups. The treatment group received ketamine HCl therapy at 0.3 mg/kg body weight/hour. The mean monocytes were counted at 0, 24, and 48 hours post-therapy. Data analysis used an independent sample t-test with α=5%.Result: Administration of ketamine therapy in septic patients treated in the ICU showed a decrease in the monocytes during observation from 0 to 48 hours post-therapy. Administration of ketamine at 48 hours had a significantly lower monocyte (5.21%) compared to control (7.67%) (p=0.012).Conclusion: Ketamine administration reduces the monocytes count in septic patients treated in the intensive care unit. Ketamine is expected to be a therapeutic option in sepsis patients.

Page 1 of 1 | Total Record : 1

 1 

Filter by Year

2023 2023


Reset
Filter By Issues
All Issue Vol. 6 No. 3 (2025): In Press Vol. 6 No. 2 (2025): May Vol. 6 No. 1 (2025): January In Press Vol 5, No 3 (2024): September Vol. 5 No. 3 (2024): September Vol 5, No 2 (2024): May Vol. 5 No. 2 (2024): May Vol 5, No 1 (2024): January Vol. 5 No. 1 (2024): January Vol 4, No 3 (2023): September Vol. 4 No. 3 (2023): September Vol. 4 No. 2 (2023): May Vol 4, No 2 (2023): May Vol. 4 No. 1 (2023): January Vol 4, No 1 (2023): January Vol 3, No 3 (2022): September Vol 3, No 2 (2022): May Vol. 3 No. 2 (2022): May Vol 3, No 1 (2022): January Vol 2, No 3 (2021): September Vol 2, No 2 (2021): May Vol 2, No 1 (2021): January Vol 1, No 3 (2020): September Vol 1, No 2 (2020): May Vol 1, No 1 (2020): January More Issue