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Yolanda Handayani
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INDONESIA
Respiratory Science
Published by Perhimpunan Dokter Paru Indonesia
ISSN : -     EISSN : 27471306     DOI : https://doi.org/10.36497/respirsci.v1i3.17
Core Subject : Health,
Health Professions Medicine & Pharmacology
Focuses on original article reviews and case reports in pulmonary and critical care medicine Scope: 1. Asthma 2. Chronic Obstructive Pulmonary Disease (COPD) 3. Lung Physiology and Sleep-Related Disorder 4. Lung Infection 5. Thoracic Oncology 6. Interstitial Lung Disease 7. Environmental Lung Disease 8. Tobacco Control 9. Occupational Pulmonary Disease 10. Pulmonary Intervention and Emergency Medicine 11. Respiratory critical care 12. Respiratory immunology and biomolecular
Arjuna Subject : Kedokteran - Kedokteran Paru dan Pernafasan
Articles 6 Documents
 1 
Search results for , issue "Vol. 3 No. 2 (2023): Respiratory Science" : 6 Documents clear
Correlation of Smoking Habit and Level of Nicotine Dependence in University Students Dio Alief Supriyanto; Tria Damayanti
Respiratory Science Vol. 3 No. 2 (2023): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v3i2.54

Abstract

Background: Smoking habits are still a global problem. One of the harmful compounds in cigarettes is nicotine which gives a dependence effect on its users because long-term exposure can cause desensitisation of nicotinic acetyhlcoline receptor. This study aimed to determine the correlation between degree of smoking habit and level of nicotine dependence in actively smoking university students. Method: A cross-sectional study was conducted using questionnaires, consisted of relating factors questionnaire (age, BMI, academic major, allowance, family smoking habits, and social environment), degree of smoking behavior questionnaire (Brinkman Index/IB), and Fagerstorm Test for Nicotine Dependence/FTND questionnaire. Results: There were 124 active smoker university students included in this study. This study found that the higher the BI score, the higher the FTND score (P<0.001; r=0.420). In addition, this study also found that there were positive correlations between age (P=0.009; r=0.223), personal income (P=0.003; r=0.261), and academic major (P=0.042) with the levels of smoking habit. There was also correlation between allowance (P=0.005; r=0.249) with level of nicotine dependence. Conclusion: These results indicate a significant moderate correlation between smoking habit with nicotine dependence among university students.
Gut-Lung Axis Anggie Indari; Menaldi Rasmin; Ari Fahrial Syam
Respiratory Science Vol. 3 No. 2 (2023): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v3i2.68

Abstract

Microbiota and the body's immune system have a two-way interaction that is interconnected. The microbiota plays a role in the formation and maturation of the immune system, on the other hand, the immune system shapes the composition and function of the microbiota. This interaction is important in maintaining the body’s immune system’s homeostasis. The human intestine contains various types of microbes that form the gut microbiota. Various studies have found that changes in the gut microbiota are associated with immunity in distal tissues such as the lung. This gives rise to the concept of a feedback relationship between the gut and lung organs called the gut-lung axis. Through this axis, changes in the composition of the gut microbiota not only cause abnormalities in the gut but also affect microbiota in the lungs and can cause disease. One of the important routes in the transmission of substances from the intestine is through the mesenteric lymphatics. Probiotics can help improve the gut’s defense mechanism. A high-fiber diet can also reduce pathogenic bacteria by increasing levels of short-chain fatty acids. Therefore, a healthy lifestyle is needed to maintain the balance of the microbiota.
Relationship Between Nutritional Status, Physical Activity, Type of Work and Smoking Activity with Fitness Level Measured by 6-Minute Walking Test on Non-staff Employees of Universitas Indonesia, Depok Menaldi Rasmin; Hilma Nur Faiza; Kemal Akbar Suryoadji; Neny Husnaini Zain; Sakinasha Siva Utami; Feni Fitriani Taufik; Dewi Friska; Nani Cahyani Sudarsono; Elisna Syahrudin
Respiratory Science Vol. 3 No. 2 (2023): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v3i2.70

Abstract

Background: Fitness is inextricable to health and has a significant correlation with the habits and behaviour of individuals such as dietary practice, sedentary behaviour, physical activities, and smoking habits. Many ways can be used to assess an individual fitness level, one of them is using the 6-minute walking test. This study aims to find the correlation between smoking intensity, nutritional status, occupation, and physical activity with the fitness level of outdoor janitors in Universitas Indonesia, Depok. Method: The research method was the cross-sectional design. The determination of the subjects was carried out by a consecutive sampling method. The data obtained results from the assessment of nutritional status, occupation, physical activity, and smoking intensity, as well as result from the 6-minute walking test. Univariate data analysis was used to assess the distribution of subjects based on sociodemographics, nutritional status, physical activity, occupation, and smoking activity. Furthermore, categorical correlative tests used were Man-Whitney, Kruskal-Wallis, and Fisher's Exact test. Results: The subjects obtained are 109 outdoor janitors from UI, Depok in which 59.6% age 18-44 years old, and 56% are male. Based on the correlative test between the fitness level and the nutritional status, value of P=0.086, as value of P between the physical activity and the fitness level is 0.0523. No significant correlation between fitness level and occupation based on location of the job, duration of work and based on the work time (P=1.00; P=1.00; P=0.108) The correlation between smoking intensity with the fitness level has value of P=0.681. Conclusion: There is no significant correlation between nutritional status, physical activity, type of work, and smoking intensity with the fitness level as measured by the 6-minute walking test method for outdoor janitors of UI, Depok.
Management of Febrile Neutropenia in Lung Cancer Haryati Haryati; Nida Amalia
Respiratory Science Vol. 3 No. 2 (2023): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v3i2.72

Abstract

Febrile neutropenia (FN) is defined as an oral temperature of >38.3° C or two consecutive measures >38°C within 2 hours accompanied by an absolute neutrophil count (ANC) of 500/L or a predicted decrease below 500/L in individuals undergoing systemic chemotherapy for cancer. FN is one of the oncological emergencies that can influence cancer patients' outcomes since it can increase morbidity, treatment delays, decrease survival, and expand costs. The incidence of FN is 3.7-28% in lung cancer patients. Mortality associated with FN episodes is 15%. FN risk factors include chemotherapy regimen, age, comorbidities, mucositis, performance status, and previous FN history. Validated predicted instruments such as The Multinational Association for Supportive Care in Cancer (MASCC) or The Clinical Index of Stable Febrile Neutropenia (CISNE) score could assist in the risk assessment of FN and determine advanced management. Effective therapy of FN requires investigation of diagnosis as soon as possible and acknowledging the potential source of infection. The prophylactic granulocyte colony-stimulating factors (G-CSF) and anti-microbial successfully reduced mortality due to FN.
Optimal Intensity of Aerobic Exercise Training for Patient With Chronic Obstructive Pulmonary Disease (COPD): Systematic Review and Meta-Analysis Christian James Ibrahim; Ari Natalia Probandari; Yusup Subagio Susanto; Jatu Aphridasari
Respiratory Science Vol. 3 No. 2 (2023): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v3i2.74

Abstract

Background: Intensity for aerobic exercise is unclear in patient with COPD. Previous systematic review comparing effects of different levels of training intensity was done in 2011 and did not reach any conclusion. We conducted this systematic review to see the differences in aerobic training intensity on various aspects of health in COPD patients with updated information. Method: We included RCTs, comparing the differences in intensity of aerobic training between groups. The primary search was done through Pubmed, Scopus, Science Direct, Proquest, and PEdro. The PEdro scale and Risk of Bias 2 tool was used to rate the studies. Lastly, we also rate the certainty of evidence using GRADE approach. The assessment was carried out by two reviewers independently. Data were extracted by one reviewer then evaluated by second reviewer. Results: We found and analysed data from four studies with total of 472 patients. The primary outcomes extracted were Disease-specific Health-Related Quality of Life (HRQoL), Activities of Daily Living (ADL), Functional exercise capacity, Dyspnea symptoms. There was a significant difference only in St George’s Respiratory Questionnaire (SGRQ) symptoms domain for HRQoL outcome (MD=5.53; 95% CI=1.08-9.97), favoured lower intensity group. No other significant results were found for any other outcomes/ outcome measures. According to GRADE, quality of the studies was very low to moderate. Conclusion: The evidence we collected is very limited and difficult to evaluate. Further research comparing higher intensity with lower intensity of aerobic training is needed.
Upper Airway Resistance Syndrome: An Underdiagnosed Sleep-related Breathing Disorder Dennis Rafi; Larasati Budiyarto
Respiratory Science Vol. 3 No. 2 (2023): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v3i2.79

Abstract

Upper Airway Resistance Syndrome (UARS) is an example of a sleep-related breathing disorder. UARS was first reported by Guilleminault in 1992 and it is known as excessive daytime sleepiness without obvious apnea or hypopnea that is characterized by more than 50% of respiratory effort-related arousals (RERAs) during sleep. The prevalence of UARS was 15% in the population of São Paulo. Although clinical manifestations, electroencephalogram (EEG) findings, and pathogenesis differ between UARS and OSA (Obstructive Sleep Apnea), it still sparked a debate among researchers as to whether UARS should be categorized as a distinct disorder. The International Classification of Sleep Disorders - Third Edition (ICSD3) integrated UARS into OSA diagnosis, resulting in underdiagnosed and undertreated patients with sleep-related breathing disorders who did not necessarily meet OSA criteria. Untreated UARS, on the other hand, has a variety of clinical consequences, including poor weight and height growth, daytime irritability, worsening of quality of life, and cardiovascular complications. Continuous positive airway pressure therapy, oral appliances, surgical management, weight reduction, and positional therapy are all considered options in the management of UARS.

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