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All Journal Indonesian Journal of Cardiology Jurnal Respirologi Indonesia Jurnal Respirasi (JR) Respiratory Science Occupational and Environmental Medicine Journal of Indonesia
Taufik, Feni Fitriani
Departemen Pulmonologi Dan Ilmu Kedokteran Respirasi Fakultas Kedokteran Universitas Indonesia, RSUP Persahabatan Jakarta
Environmental Science Health Professions Medicine & Pharmacology Nursing Public Health

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Farmakoterapi pada Upaya Berhenti Merokok Diyan Ekawati; Basuni Radi; Feni Fitriani Taufik
Jurnal Kardiologi Indonesia Vol. 36, No. 4 Oktober - Desember 2015
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v36i4.505

Abstract

Nicotine dependence is a main role in tobacco dependence. Its physiological and psychological effect make smoker difficult to quit, making low success rate in smoking cessation. Combination of different method and continuity will increase smoking cessation success rate. Evidence shown that pharmacotherapy will increase success rate. Guideline’s for smoking cessation endorse physician to use first line pharmacotherapy, but it’s clinical application still limited. Physician should be aware about possibility for side effect. Some randomized controlled trial report major cardiovascular event in first line pharmacotherapy. Recent systematic review report no correlation between first line pharmacotherapy in smoking cessation and major cardiovascular event.
Inflammatory Markers upon Admission as Predictors of Outcome in COVID-19 Patients Budhi Antariksa; Erlina Burhan; Agus Dwi Susanto; Mohamad Fahmi Alatas; Feni Fitriani Taufik; Dewi Yennita Sari; Dicky Soehardiman; Andika Chandra Putra; Erlang Samoedro; Ibrahim Nur Insan Putra Darmawan; Hera Afidjati; Muhammad Alkaff; Rita Rogayah
Jurnal Respirologi Indonesia Vol 41, No 4 (2021)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v41i4.185

Abstract

Background: Coronavirus disease 2019 (COVID-19) may cause dysregulation of the immune system, leading to hyperinflammation. Inflammatory markers can be used to predict in-hospital mortality in COVID-19 patients. This research was aimed to investigate the association between the levels of various inflammatory markers and mortality in COVID-19 patients.Methods: This study was conducted at Persahabatan National Respiratory Referral Hospital, Indonesia. Blood tests were performed upon admission, measuring the C-reactive protein, PCT, leukocyte, differential counts, and platelet count. The outcome measured was the mortality of hospitalized COVID-19 patients. Statistical analysis methods included the Mann–Whitney U test, receiver operating characteristic (ROC) analysis, and area under the curve (AUC) test.Results: Total 110 patients were included, and the laboratory values were analyzed to compare survivors and non-survivors. The non-survivor group had significantly higher leukocyte count, lower lymphocyte count, higher CRP and PCT levels, higher neutrophil-to-lymphocyte ratio (NLR), higher platelet-to-lymphocyte ratio (PLR), and lower lymphocyte-to-CRP ratio. As predictors of mortality, AUC analysis revealed that PCT, CRP, NLR, and PLR had AUCs of 0.867, 0.82, 0.791, and 0.746, respectively.Conclusions: Routine and affordable inflammatory markers tested on admission may be useful as predictors of in-hospital mortality in COVID-19 patients requiring hospitalization.
The Association Between Smoking History and Intensive Phase Treatment Success of Pulmonary Tuberculosis Patients in Dr. Zainoel Abidin Hospital Banda Aceh Risa Fitria; Feni Fitriani Taufik; Dewi Behtri Yanifitri
Jurnal Respirologi Indonesia Vol 38, No 4 (2018)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (921.127 KB) | DOI: 10.36497/jri.v38i4.47

Abstract

Background: Many diseases are associated with smoking such as malignant disease, cardiovascular, diabetes mellitus (DM), chronic obstructive pulmonary disease (COPD), arthritis, impotence, infertility, Alzheimer’s Disease, tuberculosis and others. Smoking is proven to disrupt the ciliary mucosal clearance and it is associated with an increased risk of pulmonary tuberculosis. Sputum conversion is an important indicator to assess the success of TB treatment. This study aims to determine the relation between smoking history and the success intensive phase treatment of pulmonary tuberculosis at Dr Zainoel Abidin Hospital. Method: Prospective cohort study in patients with pulmonary tuberculosis acid-fast bacilli (AFB) positive (+) smokers and non smokers who visited the Integrated Tuberculosis Care (PTT), at outpatient and inpatient pulmonary infection RSU Dr. Zainoel Abidin hospital Banda Aceh from 28 November 2015 until 1 February 2016. Results: A total of 38 subjects were divided into 2 groups (19 subjects with 19 subjects smokers and non-smokers). All subjects smokers are male while nonsmoker subjects consisted of male and female. The results of the first month study (p=0.009), there are 14 non smoker subjects with AFB conversion (73,7%) and 5 subjetcs without AFB conversion. Among smoking subjects there are 6 subjets (31.6%) with AFB conversion and 13 subjects (68.4% ) without AFB conversion. In the second month (p=0,202), more than half subjects who are non-smokers had AFB conversion, 17 subjects (89.5%) and 2 subjects (10.5%) had no AFB conversion. In smokers group there are 14 subjects (73.7% ) had AFB conversion and 5 subject (26.3%) had no conversion. Conclusion: There was a significant relation between smoking habit and the occurrence of first-month AFB sputum. (J Respir Indo. 2018; 38: 232-8)
Surfactant Protein D Level in Cement Workers Nurlinah Jalil; Sita Laksmi Andarini; Muhammad Ilyas; Feni Fitriani Taufik
Jurnal Respirologi Indonesia Vol 42, No 3 (2022)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v42i3.280

Abstract

Background: Pneumoconiosis occurs almost all over the world. Pneumoconiosis is a threat to cement workers. Serological abnormalities are observed in pneumoconiosis. Surfactant protein D (SP-D) levels were increased in workers exposed to silica. SP-D may be useful as a biomarker for the early diagnosis of pneumoconiosis but it has not been studied in Indonesia.Methods: This cross-sectional study was conducted with consecutive sampling technique. The number of subjects was 61 people, consisting of 44 workers exposed to cement and 17 controls from September 2017 to March 2018. Serum level of SP-D was measured using ELISA method. Cement exposed workers were workers in the production area and workers in quarry areas.Results: All of the study subjects were male (100%) with mean age of 42.5 years old. The youngest and oldest subjects were 21 and 55 years old, respectively. Majority of the subjects was in the normal weight group (47.7%). Based on smoking history, there were 26 subjects (59.1%) had never smoked, 12 subjects (27.3%) as smokers, and 6 subjects (13.6%) as former smokers. Duration of exposure <10 years was found in 9 subjects (20.5%) while exposure ≥10 years was observed in 35 subjects (79.5%). Good category of using self-respiratory safety instrument was observed in 5 subjects (11.4%), moderate category in 36 subjects (81.8%) and poor category in 3 subjects (6.8%). Mean serum SP-D levels in the exposed group was 111.027 ng/ml and in control group was 67.648 ng/ml. Serum SP-D levels were significantly higher in the exposed group than control group (P=0.014).Conclusion: Serum SP-D levels was statistically higher in the exposed group than in control group.
Clinical Characteristic and Outcome of COVID-19 Patients Using High Flow Nasal Oxygen in Persahabatan Hospital, Jakarta Wahyu Soebekti; Feni Fitriani Taufik; Mia Elhidsi
Jurnal Respirologi Indonesia Vol 42, No 3 (2022)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v42i3.367

Abstract

Background: Severe and critical COVID-19 patient need intensive care and even invasive mechanical ventilation. Use of high flow nasal oxygen (HFNO) in acute hypoxemic respiratory failure on non-COVID-19 patient can reduce the need for intubation while in COVID-19 patient the data is still inadequate.Methods: This is a retrospective cohort study in 62 confirmed COVID-19 patient using HFNO and treated at Persahabatan Hospital from March to July 2020. Demographic, clinical and laboratory data before HFNO and vital sign, respiratory index after 24 hours of HFNO was taken from medical record. Results: Majority of patients are men (67%), mean age 57.6 years, comorbidity is mostly hypertension and diabetes. HFNO Success outcome is 45.2%. Statistically significant difference between success and failure group is noted on respiratory rate (24 vs 28.5), pulse rate (88.14 vs 100), oxygen saturation (98 vs 94), PaO2/Fio2 (139.27 vs 73), SpO2/FiO2 (116.98 v 102.78) and ROX index (4.97 vs 3.5). Vital sign and respiratory index measured after 24 hours of HFNO showed statistically significant improvement in success group. Conclusion: HFNO can reduce intubation rate in patient with COVID-19. Vital sign and respiratory index are significantly improved in HFNO success group.
Relationship Between Nutritional Status, Physical Activity, Type of Work and Smoking Activity with Fitness Level Measured by 6-Minute Walking Test on Non-staff Employees of Universitas Indonesia, Depok Menaldi Rasmin; Hilma Nur Faiza; Kemal Akbar Suryoadji; Neny Husnaini Zain; Sakinasha Siva Utami; Feni Fitriani Taufik; Dewi Friska; Nani Cahyani Sudarsono; Elisna Syahrudin
Respiratory Science Vol. 3 No. 2 (2023): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v3i2.70

Abstract

Background: Fitness is inextricable to health and has a significant correlation with the habits and behaviour of individuals such as dietary practice, sedentary behaviour, physical activities, and smoking habits. Many ways can be used to assess an individual fitness level, one of them is using the 6-minute walking test. This study aims to find the correlation between smoking intensity, nutritional status, occupation, and physical activity with the fitness level of outdoor janitors in Universitas Indonesia, Depok. Method: The research method was the cross-sectional design. The determination of the subjects was carried out by a consecutive sampling method. The data obtained results from the assessment of nutritional status, occupation, physical activity, and smoking intensity, as well as result from the 6-minute walking test. Univariate data analysis was used to assess the distribution of subjects based on sociodemographics, nutritional status, physical activity, occupation, and smoking activity. Furthermore, categorical correlative tests used were Man-Whitney, Kruskal-Wallis, and Fisher's Exact test. Results: The subjects obtained are 109 outdoor janitors from UI, Depok in which 59.6% age 18-44 years old, and 56% are male. Based on the correlative test between the fitness level and the nutritional status, value of P=0.086, as value of P between the physical activity and the fitness level is 0.0523. No significant correlation between fitness level and occupation based on location of the job, duration of work and based on the work time (P=1.00; P=1.00; P=0.108) The correlation between smoking intensity with the fitness level has value of P=0.681. Conclusion: There is no significant correlation between nutritional status, physical activity, type of work, and smoking intensity with the fitness level as measured by the 6-minute walking test method for outdoor janitors of UI, Depok.
The Impact of Particulate Matter on the Respiratory System Yolanda Edith Pratiwi; Feni Fitriani Taufik; Januar Habibi; Adityo Wibowo
Jurnal Respirasi Vol. 9 No. 3 (2023): September 2023
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v9-I.3.2023.237-245

Abstract

Nowadays, around 50% of the world's population lives in cities and urban areas and is exposed to increasingly higher levels of air pollutants including gaseous pollutants and particulate matter (PM). The latter is a key indicator of air pollution transported into the air by a variety of natural processes and human activities. The particles' size has been directly related to their potential impact on health problems. Particles of concern include small particles with diameters of 2.5 to 10 μm (coarse particles) and smaller than 2.5 μm (fine particles). Exposure to air pollutants over a long period of time not only decompensates pre-existing diseases but also leads to pulmonary and respiratory health problems such as asthma, chronic obstructive pulmonary disease (COPD), and lung cancer even in rural areas. A thorough analysis has to be provided to address the implications for policymakers. Hence, more stringent strategies can be implemented to control air pollution and prevent its health effects.
Analysis of Knowledge of Hospital Manager about Occupational Tuberculosis and Associated Factors Prasetyo, Aditya Agung; Wibowo, Suryo; Ilyas, Muhammad; Fuady, Ahmad; Taufik, Feni Fitriani
Occupational and Environmental Medicine Journal of Indonesia Vol. 2, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction.Knowledge of hospital managers about occupational tuberculosis can affect occupational tuberculosis services in the hospital. This study aims was to identify associated factors with knowledge of hospital manager about occupational tuberculosis in order to improve occupational tuberculosis services in hospitals as seen in the four management functions. Method.Concurrent embedded mixed approaches are used in this cross-sectional study. Focus group discussions (FGD) are used in qualitative research, whereas questionnaires are used in quantitative research. The questionnaire was evaluated using the difficulty level and discriminating index tests. The ten questions were examined both univariate and bivariate. Thematic analysis was used to analyze qualitative research. The quantitative and qualitative data were then integrated. Result.Age and years of service are related to question about definition of occupational diseases and occupational diseases regulation. Education level, occupational health training, and managed occupational disease are related to question about reporting occupational tuberculosis cases. Educational background is related to question about time reporting occupational tuberculosis. Four questions have a correct response frequency of less than 50%, while six questions have a correct answer frequency greater than 50%. Conclusion.No important factor affects knowledge of hospital managers about occupational tuberculosis. Hospital managers require occupational health training to understand occupational tuberculosis.
Association between Smoking Habits and Outcomes of COVID-19 Patients in Persahabatan Hospital, Jakarta Ayesya Nasta Lestari; Feni Fitriani Taufik; Agus Dwi Susanto
Jurnal Respirologi Indonesia Vol 44, No 1 (2024)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v44i1.600

Abstract

Background: : Factors related to the severity and the outcome of coronavirus disease 2019 (COVID19) are emerging subjects of interest to be studied. Smoking has long been known to have a negative impact on the response to infection. The purpose of this study was to determine the association between smoking habits with the severity, the length of hospitalization and the outcome of COVID19 patients.Methods: This study was a prospective cohort study of COVID-19 patients admitted at Persahabatan Hospital, Jakarta, Indonesia. Subjects were included by consecutive sampling from August to October 2021. Subjects were assigned into smokers and non-smokers group. All subjects were assessed for their severity, length of hospitalization and outcome; in smoking patients, the Brinkman Index (IB) and the Fagerström Test for Nicotine Dependent (FTND) score were also recorded. Statistical tests were then carried out to assess the significant association between smoking history and the degree of severity, length of hospitalization and outcome of COVID-19 in all patients and the FTND and IB scores with the degree of severity, length of hospitalization and outcome of COVID-19 in smokers.Results: Authors found that 39/100 (39%) of participants were smokers. Smoking history had a correlation with the outcome (p=0.001) but not with the degree of severity (p=0.410) and length of hospitalization (p=0.780). Among subjects with smoking history, there were correlations found between FTND and the degree of severity and the outcome (p=0.022 and p=0.012), but not with the length of hospitalization (p=0.716). The Brinkman Index was correlated with only the degree of severity (p=0.020).Conclusion: Our study found that smoking habits were correlated with the degree of severity and outcomes in COVID-19 patients.
The 4T Approach for Smoking Cessation Compliance for Pulmonary Tuberculosis Patients in Persahabatan Referral Hospital Septauli, Kolanda Maria; Susanto, Agus Dwi; Agustin, Heidy; Ginting, Tribowo Tuahta; Taufik, Feni Fitriani
Jurnal Respirologi Indonesia Vol 44, No 1 (2024)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v44i1.578

Abstract

Background: Smoking increases the risk of tuberculosis infection and affects its treatment success rate and mortality. Most TB patients who smoke quit at the initial diagnosis, but may continue to smoke if the clinical symptoms improve. Studies show that the 4T approach (Tanya, Telaah, Tolong nasehati, and Tindak lanjut) helps smokers quit. The 4T approach was applied in Indonesia as a smoking cessation program for TB patients.Methods: We conducted a randomized controlled trial on 43 male TB patients who smoke. The trial group received a 4T approach consisting of education, counseling, and motivation to quit smoking for three months. The control group received a self-help leaflet. Smoking status, Fagerström nicotine dependence scale, exhaled carbon monoxide level, and peak expiratory flow rate were collected. We observed the subjects at months 1, 2, and 3 after quitting smoking and reported on the Motivation and Minnesota Withdrawal Scale.Results: Smoking cessation levels during months I, II, and III (Continuous Abstinence Rate I, II, and III) were higher in the trial group than in the control group. The trial group had a higher percentage of smoking cessation than the control group: until 4 weeks (66.7% vs. 54.5%), until 8 weeks (57.1% vs. 45.5%), and until 12 weeks (52.4% vs. 45.5%). The control group had higher numbers of smoking relapses (18.2% vs. 14.3%) and still smokers (18.2% vs. 9.5%) after the study. Withdrawal symptoms included an increase in appetite (44.1%), cigarette cravings (6.9%), agitation (2.3%), insomnia (2.3%), and irritability (2.3%). There were no significant differences in the withdrawal scale between groups (P=0.788), but the trial group showed better motivation to stop smoking during CAR II (P=0.043).Conclusion: The 4T approach is effective in maintaining abstinence from smoking among lung tuberculosis patients until months 1, 2, and 3 after quitting. Smoking cessation programs during tuberculosis treatment can help patients quit smoking and reduce relapse.
Co-Authors Adityo Wibowo Agus Dwi Susanto Agustin, Heidy Ahmad Fuady Ayesya Nasta Lestari Basuni Radi Budhi Antariksa Dewi Behtri Yanifitri Dewi Friska Dewi Yennita Sari Diyan Ekawati Elisna Syahrudin Erlina Burhan Ginting, Tribowo Tuahta Hera Afidjati Hilma Nur Faiza Ibrahim Nur Insan Putra Darmawan Januar Habibi Kemal Akbar Suryoadji Lestari, Ayesya Nasta Menaldi Rasmin Mia Elhidsi Mohamad Fahmi Alatas Muhammad Alkaff Muhammad Ilyas Muhammad Ilyas Nani Cahyani Sudarsono Nani Cahyani Sudarsono Neny Husnaini Zain Noor, Amira Ismi Nurlinah Jalil Prasetyo, Aditya Agung Putra, Andika Chandra Risa Fitria Rita Rogayah Sakinasha Siva Utami Samoedro, Erlang Septauli, Kolanda Maria Sita Laksmi Andarini Soehardiman, Dicky Wahyu Soebekti Wibowo, Suryo Yolanda Edith Pratiwi