cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Muhammad Ridwan
Contact Email
bukharyahmedal@gmail.com
Phone
+6281375313465
Journal Mail Official
bioexjournal@gmail.com
Editorial Address
Komplek Jasari Muslim Jl. Perjuangan, Bandar Klippa, Percut Sei Tuan, Kabupaten Deli Serdang, Sumatera Utara 20371, Indonesia
Location
Kab. deli serdang,
Sumatera utara
INDONESIA
Britain International of Exact Sciences Journal (BIoEx Journal)
Published by BIAR Publisher
ISSN : 26861216     EISSN : 26861208     DOI : https://doi.org/10.33258/bioex
Core Subject : Health, Science, Education,
Biochemistry, Genetics & Molecular Biology Chemistry Mathematics Medicine & Pharmacology Physics
Britain International of Exact Sciences Journal is a peer-reviewed journal published in January, May and September by BIAR Publisher. BIoEx Journal welcomes research paper in mathematics, physics, chemistry, biology, engineering, medical sciences, argicultural sciences and other related fields which is published in both online and printed versions.
Arjuna Subject : Matematika - Matematika (Lain-Lain)
Articles 183 Documents
 15   16   17   18   19 
Phytochemical Analysis and Therapeutic Interests of Azadirchta Indica (Meliaceae) Andrianarijaona Mamy; Ralaivaon-Dratsitonta Jumaël Edith Fabrice; Fatiany Pierre Ruphin; Robijaona Rahelivololoniaina Baholy
Britain International of Exact Sciences (BIoEx) Journal Vol 7 No 3 (2025): Britain International of Exact Sciences Journal, September
Publisher : Britain International for Academic Research (BIAR) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/bioex.v7i3.1364

Abstract

This study presents a phytochemical and structural investigation of Azadirachta indica, a plant widely used in traditional medicine in Madagascar for ailments such as malaria and fever. A systematic solid-liquid extraction of the plant's bark, employing solvents of increasing polarity, yielded various crude extracts. Subsequent phytochemical screening confirmed the abundance of key secondary metabolites, including alkaloids, tannins, polysaccharides, and saponins. The dichloromethane extract, having the highest yield, was selected for further analysis. A compound was successfully isolated from this extract using thin-layer chromatography (TLC) and preparative column chromatography. Its structure was then elucidated using a combination of one-dimensional spectroscopic techniques, including Electron Ionization Mass Spectrometry (EI-MS), 1H Nuclear Magnetic Resonance (NMR), and 13C NMR (with DEPT-135). The analysis of the spectral data, combined with a comprehensive literature review, led to the identification of the isolated molecule as 2-oxo-1,2-dihydroquinoline-4-carboxylic acid, an alkaloid with the molecular formula C10H7NO3. This compound is characterized by a two-ring system and six degrees of unsaturation, consistent with its spectral data. This research not only validates the traditional use of the plant but also provides a foundation for future pharmacological studies on this isolated compound.
Enhancing the Value of Sweet Potatoes in Madagascar: Between Food Security and Productive Capital – A Socio-Anthropological Approach Ramangarijaona Simon Ludovic; Raherimalala Etienne Stefano; Ravelo Bruno Eugène Maxime; Rakotorahalahy Njaka Herihajatsilaozana Elisabeth; Ravelonjatovo Haja Herilala; Andrianjary Myriam; Ratiarimananjatovo Narindra; Robijaona Rahelivololoniaina Baholy
Britain International of Exact Sciences (BIoEx) Journal Vol 7 No 3 (2025): Britain International of Exact Sciences Journal, September
Publisher : Britain International for Academic Research (BIAR) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/bioex.v7i3.1365

Abstract

This study focuses on the valorization of sweet potatoes in Madagascar from the perspective of food security and the accumulation of productive capital, as defined by Nurkse—that is, through the establishment of basic infrastructure. The research was conducted in the geographic areas of Ankazobe, in the northern highlands, as well as in Tsarasaotra in the Amoron'i Mania region, and in Soaindrana and Talata Ampano in the Matsiatra Ambony region. These areas are distinguished by their diverse sociocultural and economic characteristics. The central question is whether it is reasonable to consider development based on a modest, indigenous yet widespread resource like the sweet potato. The findings indicate that if its production were to increase, following a shift in the devaluing perceptions commonly associated with it, this would lead to strengthened food security. Furthermore, if basic innovations—both technical and organizational—are adopted in rural settings, the production of this tuber crop could promote the rapid accumulation of productive capital, a key element in any development process. Drawing on De Sardan’s framework of entangled social logics, which emphasizes changes in mentality, the concept of agency, and Weber’s ideal-type vision of capitalism, the objective is to move away from grand macroeconomic development theories and adopt a pragmatic approach centered on local potential. Development must therefore be rethought as a cultural process, grounded in representations and enculturated behaviors (habitus, hexis), by establishing a link between increased production and rural mentalities. The study also shows that ongoing innovations in production methods—such as those related to sweet potatoes—do not necessarily need to be expensive to trigger mechanisms for the formation of productive capital.
Phytochemical analysis of Leptadenia madagascariensis Decne (Apocynaceae) Andrianarijaona Mamy; Ralaivaon-dratsitonta Jumaël Edith Fabrice; Fatiany Pierre Ruphin; Robijaona Rahelivololoniaina Baholy
Britain International of Exact Sciences (BIoEx) Journal Vol 7 No 3 (2025): Britain International of Exact Sciences Journal, September
Publisher : Britain International for Academic Research (BIAR) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/bioex.v7i3.1368

Abstract

Leptadenia madagascariensis Decne, a woody climbing vine endemic to Madagascar, has long been utilized in traditional medicine for its therapeutic properties, despite a lack of detailed scientific investigation. This study was conducted to perform a comprehensive phytochemical analysis of the plant’s aerial parts, thereby contributing to the chemical validation of its ethnobotanical applications and supporting national conservation efforts. The powdered plant material was successively macerated with hexane, dichloromethane (DCM), and methanol, yielding crude extracts with varying polarity. Phytochemical screening of these extracts revealed a significant concentration of polysaccharides, saponins, and steroids. The DCM extract, showing a promising phytochemical profile, was selected for further purification. An initial analysis by thin-layer chromatography (TLC) indicated the presence of four dominant compounds. Subsequent separation using column chromatography resulted in the isolation of a pure compound from fractions 55 to 70. The structure of this isolated compound was determined through a combination of spectroscopic techniques, including mass spectrometry and one-dimensional nuclear magnetic resonance (NMR) spectroscopy (1H NMR, 13C NMR, and DEPT). The spectral data were compared with literature values, leading to the definitive identification of the molecule as β-Sitosterol, a common tetracyclic steroid. This finding confirms the presence of therapeutically valuable steroid compounds in L. madagascariensis, providing a scientific basis for its traditional use and a starting point for further pharmacological research.

Page 19 of 19 | Total Record : 183

 15   16   17   18   19 

Filter by Year

2019 2025


Reset
Filter By Issues
All Issue Vol 7 No 3 (2025): Britain International of Exact Sciences Journal, September Vol 7 No 2 (2025): Britain International of Exact Sciences Journal, May Vol 7 No 1 (2025): Britain International of Exact Sciences Journal, January Vol 6 No 3 (2024): Britain International of Exact Sciences Journal, September Vol 6 No 2 (2024): Britain International of Exact Sciences Journal, May Vol 6 No 1 (2024): Britain International of Exact Sciences Journal, January Vol 5 No 3 (2023): Britain International of Exact Sciences Journal, September Vol 5 No 2 (2023): Britain International of Exact Sciences Journal, May Vol 5 No 1 (2023): Britain International of Exact Sciences Journal, January Vol 4 No 3 (2022): Britain International of Exact Sciences Journal, September Vol 4 No 2 (2022): Britain International of Exact Sciences Journal, May Vol 4 No 1 (2022): Britain International of Exact Sciences Journal, January Vol 3 No 3 (2021): Britain International of Exact Sciences Journal, September Vol 3 No 2 (2021): Britain International of Exact Sciences Journal, May Vol 3 No 1 (2021): Britain International of Exact Sciences Journal, January Vol 2 No 3 (2020): Britain International of Exact Sciences Journal, September Vol 2 No 2 (2020): Britain International of Exact Sciences Journal, May Vol 2 No 1 (2020): Britain International of Exact Sciences Journal, January Vol 1 No 1 (2019): Britain International of Exact Sciences Journal, September More Issue