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Arkus
Published by HM Publisher
ISSN : 20891393     EISSN : 28085035     DOI : https://doi.org/10.37275/arkus
Core Subject : Religion, Humanities, Health, Social,
Religion Humanities Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Social Sciences
Arkus publishes original articles, article reviews, and case reports and is designed as a place of dissemination of information and scientific knowledge to develop human wealth. Arkus publishes all manuscripts in multidisciplinary fields (social sciences, sciences, technology, engineering, health, education, religion, law, economics and environmental).
Arjuna Subject : Umum - Umum
Articles 5 Documents
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Search results for , issue "Vol. 5 No. 1 (2019): ARKUS" : 5 Documents clear
Humanizing Patients: Clinical Applications Based on Physiological Principles Irfanuddin
Arkus Vol. 5 No. 1 (2019): ARKUS
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/arkus.v5i1.74

Abstract

The public's perception of the weak competence of health professional actors in Indonesia refers to complaints of lack of communication, empathy, and inadequate medical treatment. When doing therapy to patients, doctors must have a strong scientific basis for understanding basic concepts to improve the structure and function of the human body. This basic concept can be studied through the principles of physiology to be applied in the clinical realm.
Efforts to Prevent Variations of Skin Diseases in Islamic Boarding Schools through Personal Hygiene and Sanitation Education Gita Dwi Prasasty; Dwi Handayani; Dalilah
Arkus Vol. 5 No. 1 (2019): ARKUS
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/arkus.v5i1.75

Abstract

The condition of residents and environment of the boarding school which is not good has formed several variation of skin diseases that are repeated and almost similiar in every Islamic boarding school in Indonesia. This is a challenge for the Islamic boarding school community, health workers and academics to prevent, at least reduce the prevalence of these diseases. This activity was carried out in two stages, examination and education based on the results of the skin disease pattern that has been obtained from previous examinations. Education was performed online about diseases variation and how to cope them from the aspects of personal hygiene and environmental sanitation at the Pondok Pesantren Kampung Tauhiid Sriwijaya. This activity aimed to provide an coping of the variation of skin diseases that will be encountered by students and an accurate understanding of its prevention through personal hygiene and environmental sanitation.
Advances in Psoriasis Biological Agent Nopriyati; Reza Mayasari
Arkus Vol. 5 No. 1 (2019): ARKUS
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/arkus.v5i1.76

Abstract

Biological agents are proteins that have pharmacological activity, derived from living materials, either from humans, animals, or microorganisms, and can be synthesized in large quantities with the help of genetic engineering techniques (recombinant DNA techniques). Biological agents are divided into three types: monoclonal antibodies in humanized, primatized, fully human, chimeric; cytokines or recombinant human cytokines growth factors; and 3) fusion proteins. The nomenclature for receptor fusion proteins and monoclonal antibodies follows the rules established by the International Nonproprietary Names of the World Health Organization (WHO). The suffix "-cept" is used as a code to identify a drug as a receptor molecule, and "-mab" is used as a code for a monoclonal antibody. The origin of the antibody is indicated by the code "-u-" for fully human origin (e.g., secukinumab). Antibodies derived from humans and mice are humanized, code named "-Zu-" (e.g., ixekizumab or chimeric, "-xi-" (eg, infliximab).
Novel Modality in Heart Failure Treatment Alexander Edo Tondas
Arkus Vol. 5 No. 1 (2019): ARKUS
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/arkus.v5i1.77

Abstract

Heart failure is a condition when the heart is unable to meet the metabolic demands of human body. Apart from the symptoms that impair the patient’s life, heart failure also carries a higher risk of mortality and consequently a higher economic burden due to hospitalization. As the disease progresses, the management will become more complex, and shifts from drugs to devices, to prevent cardiac transplant as the final frontier in heart failure therapy. In the industrial revolution era, 3D printing and bioprinting has emerged as a novel modality in dealing with heart failure pathophysiology.
Bridging Coronary Physiology into Clinical Application of Acute Coronary Syndrome Hardi Darmawan
Arkus Vol. 5 No. 1 (2019): ARKUS
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/arkus.v5i1.123

Abstract

Normal arteries have three layers of structure, tunica intima, tunica media, and tunica adventitia. Intima tunica is the deepest layer of coronary arteries in which there are antithrombotic molecules such as heparin sulfate, thrombomodulin, and plasminogen activator. In addition, tunica intima also contains substances that regulate the contraction of tunica smooth muscle cell media, called nitric oxide (vasodilators) and prostacyclin (vasoconstrictors). Tunica intima and tunica media seem to be directly related to the atherosclerosis process. Meanwhile, the role of tunika adventisia is unknown. The accumulation of atherosclerotic lesions and hemodynamic stress factors and the degradation of extracellular matrix will cause susceptibility of atherosclerotic plaque fibrous capsules to rupture and form thrombus. Thrombus that occurs in the coronary condition causes acute coronary syndrome, characterized by typical symptoms such as chest pain depending on the thrombus formed. In studying acute coronary syndromes, of course it cannot be separated from understanding the physiology of coronary arteries and the process of atherosclerosis. Therefore, this article aims to briefly explain coronary physiology.

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