cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
HENNY SYAPITRI
Contact Email
heny_syahfitri86@yahoo.com
Phone
+6285359022627
Journal Mail Official
ojs.usmindonesia19@gmail.com
Editorial Address
http://e-journal.sari-mutiara.ac.id/index.php/2/Editorial-Team
Location
Kota medan,
Sumatera utara
INDONESIA
Jurnal Farmanesia
Published by Universitas Sari Mutiara Indonesia
ISSN : """"     EISSN : 25282484     DOI : https://doi.org/10.51544/jf.v8i2
Core Subject : Health,
Medicine & Pharmacology
Jurnal Farmanesia dengan E-ISSN: 2528-2484 merupakan jurnal resmi yang diterbitkan oleh Program Studi S1 Farmasi Fakultas Farmasi dan Ilmu Kesehatan Universitas Sari Mutiara Indonesia, yang artikelnya dapat diakses dan diunduh secara online oleh publik (open access journal). Jurnal ini merupakan jurnal peer-review yang diterbitkan dua kali setahun dengan topik keunggulan hasil penelitian di bidang pelayanan dan praktik kefarmasian, teknologi farmasi, dan disiplin ilmu kesehatan yang berkaitan erat. Jurnal ini menerima teks bahasa Indonesia. Berikut ini adalah area penelitian yang menjadi fokus jurnal ini: 1. Farmakologi 2. Farmasetika 3. Biologi Farmasi 4. Kimia Farmasi 5. Farmakognosi 6. Fitokimia
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 20 Documents
 1   2 
Search results for , issue "Vol 5 No 1 (2018): Jurnal Farmanesia" : 20 Documents clear
SKRINING FITOKIMIA DAN UJI AKTIVITAS ANTIDIABETES DARI EKSTRAK ETANOL DAGING BUAH ALPUKAT (Persea americana Mill.) Yettrie Simarmata; Kesaktian Manurung; Karnerius Harefa; Mei Sri Rezeki Hasibuan
Jurnal Farmanesia Vol 5 No 1 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (451.698 KB)

Abstract

Diabetes mellitus is a set of symptoms that arise in a person characterized by blood glucose levels exceeding normal (hyperglycemia) due to a lack of insulin in the body. One of the medicinal plants that can be used is avocado flesh. This study aims to determine the antidiabetic activity of avocado pulp extract (Persea americana Mill) against male white rats. This study used 25 male white rats divided into 5 groups, namely the negative control group CMC-Na 1%, the positive control group glibenclamide 0.45 mg/kg BW, the EEBA test group at doses of 50, 100, 200 mg/kg BW. The results of the one-way ANOVA analysis of the Tukey HSD test showed that the administration of EEBA at a dose of 100 mg/kg BW and EEBA at a dose of 200 mg/kg BW had a significant difference with a significance value of 0.024 and 0.026 and EEBA at a dose of 50 mg/kg BW had no significant difference with the significance 0.275. Based on the results of the study, it can be concluded that EEBA doses of 50, 100, 200 mg/kg BW have antidiabetic activity.
PENENTUAN KADAR VITAMIN C PADA JERUK MANIS (Citrussinensis) MENGGUNAKAN METODE TITRASI TITRASI NA-2,6 DICHLOROPHENOL INDOPHENOL DAN SPEKTROFOTOMETRI Siti Nurbaya; Muhammad Taufik; Artha Yuliana Sianipar; Zulfan Zulfan
Jurnal Farmanesia Vol 5 No 1 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (244.609 KB)

Abstract

Vitamin C is one of the vitamins that is needed by humans and also one of the water-soluble vitamins, Vitamin C plays a role in the formation of intercellular collagen. For the solubility of vitamins B1, B2, B3, B5, B6, B7, B9, B12, and C are included in the types of water-soluble vitamins, and for the solubility vitamins A, D, E, and K are included in the types of soluble vitamins in fat. Vitamin C functions as an antioxidant and counteracts free radicals that can damage cells. Sources of vitamins are fresh fruits and vegetables. Sweet orange fruit contains vitamin C which is quite high. This study aims to determine and compare the results of vitamin C levels in sweet oranges using the Na 2,6 Dichlorophenol Indophenol titration method and spectrophotometry. The content of vitamin C using Na 2.6 Dichlorophenol Indophenol titration is 0.042%, while the content of vitamin C in sweet oranges using the UV-Vis spectrophotometry method produces levels of 0.351%. These results, shows that the levels of vitamin C obtained by using the UV-Vis spectrophotometry method are higher than those obtained by the iodometric method.
FORMULASI EKSTRAK TONGKOL JAGUNG (Zea mays L.) SEBAGAI TABIR SURYA DALAM SEDIAAN LOTION UNTUK WAJAH Maringan Silitonga; Pandapotan Nasution; Cut Masyithah Thaib; Mei Revolinda Haloho
Jurnal Farmanesia Vol 5 No 1 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (191.89 KB)

Abstract

Corn cobs (Zea mays L.) can be used as sunscreen because it contains phenolic compounds. The purpose of this study was to determine the characteristics of the physical and chemical properties of sunscreen lotion preparations of corncob ethanol extract and the formula and concentration that had the highest effectiveness in the value of Sun Protection Factor (SPF). The lotion was chosen because it is a topical preparation that is often used by the community. Corn cob powder was extracted by the maceration method. The results were formulated with extract concentrations, formulation I (5%), formulation II (10%), and formulation III (15%). The three formulas were tested for organoleptic, pH test, homogeneity, and lotion type. The resulting data were analyzed descriptively. The results showed that all formulas with varying concentrations of extracts had good physicochemical characteristics during storage based on the results of pH, homogeneity, organoleptic, and emulsion-type tests. Corncob ethanol extract sunscreen lotion in Formula 1 (5%) has an SPF value of 2 (UV-A rays) and an SPF value of 7 (UV-B rays). Formula 2 (10%) has an SPF value of 2,3 (UV-A rays) and has an SPF value of 9 (UV-B rays) and Formula 3 (15%) has an SPF value of 3 (UV-A rays) and has a value of SPF 12 (UV-B Rays).
PERBANDINGAN UJI AKTIVITAS ANTI DIABETES EKSTRAK ETANOL BUAH PARE (Momordicacharantia L.) DANDAUN LIDAH BUAYA (Aloe vera L.) PADA MENCIT JANTAN Erly Sitompul; Supartiningsih Supartiningsih; Samsia Yolanda Sari
Jurnal Farmanesia Vol 5 No 1 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (498.224 KB)

Abstract

Diabetes is a non-communicable degenerative disease that will increase in number in the future. This is evidenced by the increasing incidence of diabetes every decade. Bitter gourd and aloe vera are an alternative in treating Diabetes Mellitus because these plants contain saponins, flavonoids, and polyphenols (strong antioxidants), as well as glycosides cucurbitacin, momordicin, and charantin that can lower blood sugar, saponins, flavonoids, and alkaloids. This study aims to determine secondary metabolite compounds, anti-diabetic activity, and the combination of aloe vera extract and bitter melon extract that has antidiabetic activity. The method used in this study is an experimental method, namely testing the antidiabetic effect of extracts obtained from ethanol of bitter melon and aloe vera leaves on alloxan-induced mice. The results obtained from the research are that the administration of aloe vera extract 150 mg/kg BW and 200 mg/Kg BW, the group with the ethanol extract of bitter melon 150 mg/kg BW and 200 mg/Kg BW showed a very good effect on reducing BGD. This means that aloe vera extract 150 mg/kg BW and 200 mg/Kg BW, the group given ethanol extract of bitter melon 150 mg/kg BW and 200 mg/Kg BW had good antidiabetic activity.
ANALISIS KADAR KALSIUM DAN BESI PADA DAUN TANAMAN BAYAM MERAH (Alternantheraamoena Voss) DAN DAUN TANAMAN BAYAM KAKAP (Amaranthus hybridus L) SECARA SPEKTROFOTOMETRI SERAPAN ATOM Ahmad Gazali Sofwan; Siti Nurbaya; Adiansyah Adiansyah; Pontisari Sitanggang
Jurnal Farmanesia Vol 5 No 1 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (484.304 KB)

Abstract

Spinach (Amaranthus spp) is a leaf vegetable plant that is highly nutritious and favored by all levels of society. According to information, spinach plants can be used as an additional intake in the prevention of osteoporosis (bone loss) and anemia (lack of blood) because of the high calcium and iron content in them. Two types of spinach are known in the community, namely red spinach (Alternanthera amoena Voss) and spinach snapper (Amaranthus hybridus L). The purpose of this study was to determine the levels of calcium and iron in red spinach and snapper spinach leaves. The assay was carried out using an atomic absorption spectrophotometer with an air-acetylene flame. Quantitative analyzes were carried out at wavelengths of 422.7 nm for calcium and 248.3 nm for iron. The results showed that the levels of calcium and iron obtained with the levels of calcium and iron listed in the literature were different. The results also showed that there were differences in calcium and iron levels between red spinach and snapper spinach. Calcium levels in red spinach and snapper spinach leaves were 26.8016 mg/100g and 24.2759 mg/100g, respectively. The levels of iron in red spinach and snapper spinach leaves were 714.2621 mg/100g and 236.5369 mg/100g, respectively.
PENGGUNAAN JERUK NIPIS (Citrus aurantifolia) DAN LIDAH BUAYA (Aloe vera L.) SEBAGAI SEDIAAN HAIR TONIC Elly Nurita; Cut Masyithah Thaib; Adiansyah Adiansyah; Irmayanti Hutasoit
Jurnal Farmanesia Vol 5 No 1 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (363.814 KB)

Abstract

Lignin compounds and polysaccharides, the nutritious substances in aloe vera, are useful as a carrier for the nutrients needed by the skin to repair hair roots, strengthen and stimulate hair growth. The purpose of this study was to determine the efficacy of the combination of lime extract and aloe vera extract as a hair tonic preparation for hair growth. Lime and aloe vera extracts were obtained by maceration method using 96% ethanol as solvent. The combination of lime extract and aloe vera extract is formulated to be a hair tonic, with a combination of 1 (1%:1%), combination 2 (2%:1%), and combination 3 (1%:2%). Then evaluate the stability of the hair tonic preparation, homogeneity, pH, hair growth activity, and hair weight of rabbits. The results of the stability test of the hair tonic preparation of a combination of lime extract and aloe vera extract did not change color, shape, and odor. The results of the homogeneity examination of the formulations of formulas 1, 2, and 3 were homogeneous. The result of pH observation was that the higher the concentration of the combination of lime extract and aloe vera extract, the higher the pH of the preparation. The results of the measurement of rabbit fur length showed that the highest hair growth rate was formula 3 combinations (1%:2%). The results of the three formulations of the combination of lime extract and aloe vera extract showed that the longer the hair growth of the rabbit, the heavier the weight of the rabbit's hair.
UJI AKTIVITAS EKSTRAK ETANOL DAUN SAWO MANILA (Manikara zapota L.) TERHADAP BAKTERI Bacillus cereus Kesaktian Manurung; Adiansyah Adiansyah; Yosy Cinthya Eriwaty Silalahi; Sry Hayati
Jurnal Farmanesia Vol 5 No 1 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (392.773 KB)

Abstract

Sawo manila (Manikara zapota L.) merupakan salah satu bahan alam sebagai obat alternatif yang telah banyak dimanfaatkan oleh masyarakatnya juga untuk mengobati berbagai penyakit dan sawo merupakan tanaman dari family Sapotaceae yang digunakan dalam pengobatan tradisional. Ekstrak daun sawo manila mengandung alkaloid, tanin, flavonoid, dan saponin yang diketahui memiliki aktivitas antibakteri. Tujuan penulisan surat ini adalah untuk mengetahui aktivitas antibakteri sawo manila (Manikara zapota L.) terhadap bakteri Bacillus cereus. Penelitian ini menggunakan metode eksperimen, dengan metode ekstraksi maserasi dan metode chakra difusi untuk aktivitas antibakteri. Hasil penelitian menunjukkan bahwa simplisia memiliki kadar air 9,30%, larut dalam air 23,72%, kadar larut air ekstrak 31,15%, kadar abu total 1,11%, dan kadar ask tidak larut asam. 0,30%. Percobaan aktivitas anti bakteri ekstrak etanol daun sawo terhadap daya hambat bakteri bacillus cereus pada konsentrasi 20%, 40%, 60%, 80% dan 100% yaitu 12,62 mm, 15,0 mm, 15,74 mm, 16,9 mm , dan 18,78 mm, control positif menggunakan kotrimoksazol dan luas zona hambat 21,5 mm daun sawo manila dapat menghambat Bacillus cereus.
UJI AKTIVITAS ANTIBAKTERI HAND SANITIZER DARI EKSTRAK ETANOL BUNGA ROSELLA (Hibiscus Sabdariffa L) TERHADAP PERTUMBUHAN BAKTERI Staphylococcus aureus Adiansyah Adiansyah; Siti Maimunah; Elly Nurita Sitorus; Nurul Hazlinda
Jurnal Farmanesia Vol 5 No 1 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (198.819 KB)

Abstract

In Indonesia with a tropical climate, rosella can thrive. Roselle plant (Hibiscus sabdariffa L.) is well known for its petals which can be used as a health drink that can cure various diseases. Roselle flower (Hibiscus sabdariffa L.) contains nutritious substances such as alkaloids, flavonoids, tannins, terpenoids, which have antibacterial properties. The purpose of this study was to determine the antibacterial hand sanitizer ethanol extract of Rosella flower (Hibiscus sabdariffa L) had good quality and stability against Staphylococcus aureus bacteria. This research was experimental, including rosella flower sample collection, simplicia drying, extract making using a rotary evaporator, phytochemical screening, characteristics of the antibacterial activity test preparation of hand sanitizer with agar diffusion method using paper discs. Roselle flower ethanol extract can be made as Hand sanitizer in spray preparations and has antibacterial activity. The difference in the concentration of the ethanol extract is 2.5%, the inhibition zone is 6.8 mm, 5% is the inhibition zone is 7.27 mm, 7.5% is the inhibition zone is 7.72 mm and 10% is 12.35 mm. The ethanolic extract of the Roselle flower (Hibiscus sabdariffa L) can be used as a hand sanitizer preparation. It has antibacterial activity against Staphylococcus aureus bacteria and is the most effective at a concentration of 10% of 12.35 mm.
UJI AKTIVITAS ANTIDIABETES EKSTRAK ETANOL DAUN SENDOK (Plantago major L.) PADA TIKUS PUTIH JANTAN YANG DIINDUKSI ALOKSAN Supartiningsih Supartiningsih; Jon Kenedy Marpaung; Adiansyah Adiansyah; Hapsah Junita Siregar
Jurnal Farmanesia Vol 5 No 1 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (460.731 KB)

Abstract

Spoon leaves contain active ingredients, namely tannins, flavonoids, sterols, and polysaccharides. These compounds may be responsible for providing a hypoglycemic effect. This study aims to determine the characterization of the ethanol extract of spoon leaves in male white rats induced by alloxan. Diabetic rats were grouped into five treatment groups, each group consisted of 5 rats. Group I (CMC-Na suspension 0.5% w/v), group II (glibenclamide 0.45 mg/kg BW); Groups II, III, and IV (EEDS doses of 200 mg/kg BW, 400 mg/kg BW, and 600 mg/kg BW) were taken orally for 15 consecutive days. Furthermore, the measurement of glucose levels was observed and measured with a glucometer on days 3, 5, 7, 9, 11, 13, and day 15. The results of the examination of simplicia characteristics showed that the water-soluble extract content was 13.47%, the ethanol-soluble extract content was 12.84%, the total ash content was 3.29%, and the acid insoluble ash content was 0.29%. The results of the analysis of the administration of EEDS showed a significant effect of reducing blood glucose levels in mice compared to the 1% CMC-Na control group. The best decrease in blood glucose levels on the 15th day was shown in the 600 mg/kg BW dose group. Statistical test results (a = 0.05) showed that EEDS at a dose of 400 mg/kg BW and a dose of 600 mg/kg BW were not significantly different from glibenclamide at a dose of 0.45 mg/kg BW.
FORMULASI SEDIAAN KRIM LULUR KOPI ARABIKA (Coffea arabica) SEBAGAI ANTI-AGING Vivi Purwandari; Maringan Silitonga; Cut Masyithah Thaib; Isra Kristina Sitohang
Jurnal Farmanesia Vol 5 No 1 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (525.316 KB)

Abstract

Coffee is one of the plantation commodities that has a fairly high economic value among other plantation crops and plays an important role as a source of foreign exchange for the country. Coffee contains important compounds such as antioxidants and caffeine which functions as anti-aging so that it can be used as an anti-aging ingredient in the form of a scrub. The purpose of this study was to determine whether coffee can be formulated in the form of cream as an anti-aging, and in the form of a body scrub cream. The research method using experimental includes the collection of Arabica coffee ingredients, making formulations of Arabica coffee scrub cream preparations, and description of the quality of Arabica coffee cream body scrub preparations. Data analysis in this study used descriptive analysis by presenting the frequency distribution table of each study. The results of the study found that the difference in the concentration of Arabica coffee (Coffea arabica) in body scrub cream preparations had an effect with the best concentration of 15% compared to 5%, 10%, and blank concentrations, and the use of body scrub cream preparations containing Arabica coffee. (Coffea arabica) 15% showed improvement in skin condition for the better, during four weeks of treatment. Thus, Arabica coffee (Coffea arabica) can be formulated in the form of body scrub cream as anti-aging.

Page 1 of 2 | Total Record : 20

 1   2 

Filter by Year

2018 2018


Reset
Filter By Issues
All Issue Vol 12 No 1 (2025): Jurnal Farmanesia Vol 11 No 2 (2024): Jurnal Farmanesia Vol 11 No 1 (2024): Jurnal Farmanesia Vol 10 No 2 (2023): Jurnal Farmanesia Vol 10 No 1 (2023): Jurnal Farmanesia Vol 9 No 2 (2022): Jurnal Farmanesia Vol 9 No 1 (2022): Jurnal Farmanesia Vol 8 No 2 (2021): Jurnal Farmanesia Vol 8 No 1 (2021): Jurnal Farmanesia Vol 7 No 2 (2020): Jurnal Farmanesia Vol 7 No 1 (2020): Jurnal Farmanesia Vol 6 No 2 (2019): Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia Vol 5 No 2 (2018): Jurnal Farmanesia Vol 5 No 1 (2018): Jurnal Farmanesia Vol 4 No 2 (2017): Jurnal Farmanesia Vol 4 No 1 (2017): Jurnal Farmanesia Vol 3 No 1 (2016): Jurnal Farmanesia Vol 2 No 1 (2015): Jurnal Farmanesia Vol 1 No 1 (2014): Jurnal Farmanesia More Issue