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Syamsurizal
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INDONESIA
TROPICAL GENETICS
Published by Genetikawan Muda Indonesia
ISSN : -     EISSN : 27984710     DOI : -
Core Subject : Health, Science, Agriculture, Engineering,
Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Decision Sciences, Operations Research & Management Medicine & Pharmacology
Genetics Basics Classical Genetics Theoretical and Applied Genetics Molecular Genetics Cytogenetics Bioinformatics Genetic Diversity Population Genetics Genetic Engineering Forensic Genetics Behavioural Genetics Advanced Genetics and Evolution Clinical Genetics and Genetic Counselling Genomics
Arjuna Subject : Biokimia, Genetika dan Biologi Molekuler - Biokimia, Genetika dan Biologi Molekuler (Lain-Lain)
Articles 5 Documents
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Search results for , issue "Vol. 2 No. 2 (2022):" : 5 Documents clear
Morphometric characterization and genetic distance in bitches (oryctolagus cuniculus) in several regions in Indonesia Auliani Arafah; Abdul Razak
Tropical Genetics Vol. 2 No. 2 (2022):
Publisher : Genetikawan Muda Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/tg.v2i2.25

Abstract

Rabbits are a group of animals that are very popular and enjoy doing the community. Rabbits in general have high biological and economic potential to produce quality meat, skin and hair, as well as pets (ornamental) and as modern business farming. Rabbits are well known to the people of Indonesia and developed mostly for rabbit farming. To obtain information about this, this study will discuss the objective of knowing the morphometric characteristics and genetic distances of rabbits. The parameters observed were head length, head width, ear length, ear width, chest circumference, chest width, chest width, humerus bone length, radius-ulna bone length, tibia bone length, and body length. The results of body variables measurement in FG rabbits had a higher mean for body size PK (12.64 cm), PTL (13.59 cm), LTL (6.47 cm), PH (9.52 cm), PRU (8, 95 cm) and PB (41.97 cm) for body size compared to other families. Genetic distance shows that it has a fairly close genetic distance (0.63106), while the farthest genetic distance is found in Rexb rabbits and ES rabbits, which is as far as 6.96749. Estimation of genetic distances and tree phenogram construction results from the estimation of kinship between other rabbit clumps.
Review Article: SNP rs11196205 Transcription Factor 7 Like 2 (TCF7L2) as a Metabolic Disorder Genetic Marker Elsa Badriyya; Siti Fatimah Putri Hasyul
Tropical Genetics Vol. 2 No. 2 (2022):
Publisher : Genetikawan Muda Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/tg.v2i2.26

Abstract

A metabolic disorder appears when unusual chemical reactions impair the metabolism process in the body. This condition affects how the body distributes and processes macronutrients, including protein, lipids, and carbohydrates. Transcription Factor 7 Like 2 (TCF7L2) is a 217,460 bp gene, found in chromosome 10q25, and encodes the High Mobility Group (HMG) box with a role in the Wnt signaling pathway. The Wnt signaling pathway involves several processes during development, healthy homeostasis, and illness. The reactions that follow the pathway's activation regulate both proliferation and differentiation. Single Nucleotide Polymorphism (SNP) in the TCF7L2 gene has been linked to a variety of metabolic disorders incidence. SNP rs11196205 was found to have a significant association with type 1 and type 2 diabetes mellitus, gestational diabetes mellitus, glucose homeostasis, obesity-related parameters, and renal function. Mechanism SNPs causing the metabolic disorder are still unexplained, but SNPs are suspected to affect transcription and splicing processes. SNPs of TCF7L2 genes are reported to affect proinsulin conversion to insulin, decrease incretin hormone production, and decrease insulin sensitivity throughout the body. It can conclude that the screening for the SNP can be a sign of metabolic process abnormalities, especially in diabetes Mellitus.
Unique Pattern of Hypertension Fingerprints S. Syamsurizal; Sudarni; Rapidah; Elsa Badriyya; Sintia Putri
Tropical Genetics Vol. 2 No. 2 (2022):
Publisher : Genetikawan Muda Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/tg.v2i2.27

Abstract

The fingerprint pattern (dermatoglyphics) of each individual is not the same. Fingerprint patterns are often used as an identification tool in criminal cases and disease diagnosis. Fingerprint patterns for health diagnosis are usually diseases caused by genetic factors, for example hypertension. The purpose of this study was to describe the characteristics of fingertip dermatoglyphics of hypertensive patients. The research sample was 60 people consisting of 30 people with hypertension who visited the DR. M. Djamil Padang and controls 30 non-hypertension (normal) people from Biology FMIPA UNP students. Simple random sampling. The research variables are tendril patterns on the fingertips, the number of tendrils on the fingertips and the atd angle on the palms. The Chi-square test was used to analyze the tendril pattern data of hypertension patients. To compare the number of tendrils and the angle atd, a t-test was used. The results showed that the arch fingerprint pattern is a unique character in hypertensive patients.
Genotyping Of Sumatera Local Variety Of Citrus Using Random Amplified Polymorphism DNA (RAPD) Technique Rinti Mutiara Sari; Afifatul A Achyar; Yuni Ahda; Dwi Hilda Putri
Tropical Genetics Vol. 2 No. 2 (2022):
Publisher : Genetikawan Muda Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/tg.v2i2.29

Abstract

Indonesia memiliki varietas jeruk lokal yang tidak kalah dengan jeruk impor, terutama dalam hal kesegaran buah. Namun, masyarakat lebih tertarik dengan warna kulit jeruk sehingga masyarakat lebih memilih jeruk impor ketimbang jeruk lokal, khususnya di Sumatera. Oleh karena itu, perlu dilakukan upaya pelestarian dan peningkatan karakteristik jeruk ini untuk meningkatkan kualitasnya melalui pemuliaan tanaman. Penelitian ini bertujuan untuk mengoptimalkan metode isolasi DNA sampel buah jeruk dengan Chelex-TE dan untuk mengetahui profil genetik jeruk lokal Sumatera dan jeruk impor menggunakan genotipe RAPD. Sampel yang digunakan adalah beberapa jeruk lokal di Sumatera (Citrus Siam Gunung Omeh, Citrus Madu, Citrus Keprok Maga, Citrus Keprok Brastepu dan Citrus Pasaman) dan Citrus impor (Citrus Sunkist, Citrus Clemengold, Citrus Murkot dan Citrus Wokam). DNA diisolasi menggunakan metode Chelex-TE 10% yang dioptimalkan untuk beberapa parameter seperti ukuran butir, kulit buah dan daun. RAPD dilakukan dengan menggunakan 10 primer RAPD. Hasil penelitian menunjukkan bahwa metode isolasi Chelex Chelex-TE 10% yang optimal adalah ukuran sampel 1 butir. Amplifikasi jeruk lokal Sumatera dan jeruk impor menggunakan 10 primer tunggal menghasilkan pita polimorfik. Nilai kesamaan jaccard menunjukkan bahwa kelima sampel jeruk tersebut merupakan varietas lokal Sumatera yang diamati memiliki variasi genetik yang tinggi dibandingkan dengan keempat jeruk impor tersebut. Indonesia memiliki varietas jeruk lokal yang tidak kalah dengan jeruk impor, terutama dalam hal kesegaran buah. Namun, masyarakat lebih tertarik dengan warna kulit jeruk sehingga masyarakat lebih memilih jeruk impor ketimbang jeruk lokal, khususnya di Sumatera. Oleh karena itu, perlu dilakukan upaya pelestarian dan peningkatan karakteristik jeruk ini untuk meningkatkan kualitasnya melalui pemuliaan tanaman. Penelitian ini bertujuan untuk mengoptimalkan metode isolasi DNA sampel buah jeruk dengan Chelex-TE dan untuk mengetahui profil genetik jeruk lokal Sumatera dan jeruk impor menggunakan genotipe RAPD. Sampel yang digunakan adalah beberapa jeruk lokal di Sumatera (Citrus Siam Gunung Omeh, Citrus Madu, Citrus Keprok Maga, Citrus Keprok Brastepu dan Citrus Pasaman) dan Citrus impor (Citrus Sunkist, Citrus Clemengold, Citrus Murkot dan Citrus Wokam). DNA diisolasi menggunakan metode Chelex-TE 10% yang dioptimalkan untuk beberapa parameter seperti ukuran butir, kulit buah dan daun. RAPD dilakukan dengan menggunakan 10 primer RAPD. Hasil penelitian menunjukkan bahwa metode isolasi Chelex Chelex-TE 10% yang optimal adalah ukuran sampel 1 butir. Amplifikasi jeruk lokal Sumatera dan jeruk impor menggunakan 10 primer tunggal menghasilkan pita polimorfik. Nilai kesamaan jaccard menunjukkan bahwa kelima sampel jeruk tersebut merupakan varietas lokal Sumatera yang diamati memiliki variasi genetik yang tinggi dibandingkan dengan keempat jeruk impor tersebut.
Dermatoglyphic Analysis of Asthma Sufferers in a Population Of Students At The Faculty of Mathematics and Science, Universitas Negeri Padang Velina Salsabil; Afifatul Achyar; Yuni Ahda
Tropical Genetics Vol. 2 No. 2 (2022):
Publisher : Genetikawan Muda Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/tg.v2i2.30

Abstract

Asthma is a disease defined as chronic inflammation of the airways which is characterized by recurrent coughing and shortness of breath. Dermatoglyphs are the appearance of tendrils and tendril patterns on the fingers, palms, toes and soles. Dermatoglyph is used as an aid in the detection of a number of diseases that have a strong heritable basis and is also used to detect abnormalities. This study aims to analyze and compare the patterns of dermatoglyphics in asthma sufferers and non-asthmatics on the fingertips. This type of research is descriptive research with cross sectional sampling method. Samples were taken from the student population of the Faculty of Mathematics and Natural Sciences, Padang State University as many as 100 samples of fingerprint patterns. The results obtained showed that there was a significant difference in the number of arch fingerprint patterns of asthmatics compared to normal individuals. Seeing this significant difference in numbers indicates a possible link between fingerprint patterns and asthma phenotypes.

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