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Pharmaceutical Sciences and Research (PSR)
Published by Universitas Indonesia
ISSN : 24072354     EISSN : 24770612     DOI : https://doi.org/10.7454/psr
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Aims Pharmaceutical Sciences and Research (PSR), an international, peer-reviewed, open access, and official journal from Faculty of Pharmacy, Universitas Indonesia, aims to disseminate research results and findings in Pharmaceutical Sciences and Practices. Major area of interest is natural products in drug discovery and development. We also consider other areas related to pharmaceutical sciences and practices. PSR publishes content in English language to promote the sharing of knowledge to international scholars. PSR publish 5 types of articles: 1. Original article 2. Case report 3. Case series 4. Review article 5. Mini review article Scope Researches in Pharmaceutical Sciences and Practices which are covered by PSR are within these subject areas: - Pharmacognosy and Phytochemistry - Pharmaceutical Chemistry - Pharmaceutical Technology - Pharmaceutical Biotechnology - Clinical Pharmacy - Pharmacology-Toxicology - Social and Administrative Pharmacy, including Pharmacoeconomy
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Articles 12 Documents
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Search results for , issue "Vol. 5, No. 1" : 12 Documents clear
Sensitivity of Escherichia coli Bacteria Towards Antibiotics in Patient with Diabetic Foot Ulcer Sari, Rafika; Apridamayanti, Pratiwi; Puspita, Indira Diah
Pharmaceutical Sciences and Research Vol. 5, No. 1
Publisher : UI Scholars Hub

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Abstract

Chronic complication of diabetes mellitus is diabetic foot ulcers. Diabetic foot ulcer can be defined as an open wound in the feet which will become infected as the result of high blood sugar levels that develops and become place of bacteria. One of the bacteria in diabetic foot ulcer is Escherichia coli. Imprecise use of antibiotics in the treatment of diabetic foot ulcers can cause antibiotic resistance to bacteria. This study aims to determine antibiotic sensitivity of Escherichia coli bacteria in diabetic foot ulcer Wagner grade III and IV. Samples of diabetic foot ulcer swab’s with Wagner grade III and IV were taken as Consecutive sampling. Identification of Escherichia coli bacteria is done by using a biochemical test and Gram stain test. Antibiotic sensitivity test is conducted by using Kirby Bauer’s disc of diffusion method. Escherichia coli bacteria that were tested are sensitive to amikacine, gentamicine, ciprofloxacin, levofloxacine, ceftriaxone, cefotaxime, imipenem and meropenem antibiotics but showed resistant to cefadroxil.
Evaluasi Rasionalitas Penggunaan Obat Antihipertensi di Puskesmas Siantan Hilir Kota Pontianak Tahun 2015 Untari, Eka Kartika; Agilina, Alvani Renata; Susanti, Ressi
Pharmaceutical Sciences and Research Vol. 5, No. 1
Publisher : UI Scholars Hub

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Abstract

Hypertension is widely known as cardiovascular disease. In addition to resulting heart failure, hypertension can result in kidney failure and cerebrovascular disease. This study was aimed to determine the percentage of treatment rationality of hypertensive patient treatment outpatient in Puskesmas Siantan Hilir Pontianak 2015 which includes the appropriate indication, appropriate drug, appropriate patient, and appropriate dose based on the guideline JNC 7. This study was cross-sectional study using medical records of outpatient hypertension patients in 2015. The total of sample analyzed in this research were 92 medical records of hypertension patients from 118 medical records. The percentage of using the angiotensin converting enzym inhibitor (captopril) was 47.46%; calcium channel blocker (amlodipine) was 34.75%; thiazid diuretic (hydrochlorothiazid) was 16.10%; loop diuretic (furosemid) was 0.85%; and potassium sparing (spironolactone) was 0.85%. The rasionality of hypertensive therapy in patients in this study were 100% appropriate indication; 70.65% appropriate drug; 100% appropriate patient; and 98.91% appropriate dose. The conclusion of this study is that overall treatment that meets all four rational treatment criterias was 69.56%.

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