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INDONESIA
Berita Kedokteran Masyarakat
ISSN : 02151936     EISSN : 26148412     DOI : https://doi.org/10.22146/bkm.v37i2.2320
Core Subject : Health,
Berita Kedokteran Masyarakat (BKM Public Health and Community Medicine) is a peer-reviewed and open access journal that deals with the fields of public health and public medicine. The topics of the article will be grouped according to the main message of the author. This focus covers areas and scope related to aspects of: - Epidemiology - Infectious diseases control - Clinical Epidemiology - Environmental Health - Occupational Health - Healthy City - Public Health and Primary Health Care - School of Health Promotion - Healthy lifestyles - Health promotion - Health and Social Behavior - Tobacco and smoking - Adolescent Health - Public Health Nutrition - Maternal and Child Health - Reproductive Health - Population Health - Health of Vulnerable People - Social Determinants of Health - Water, Sanitation and Hygiene - Human Resource Management
Articles 7 Documents
Search results for , issue "Vol 23, No 3 (2007)" : 7 Documents clear
Histopathological Features of Early Onset Indonesian Breast Cancer Pointing to Brca1/2 Germline Mutations Purnomosari Van Der Groep P, Wahyono A, Aryandono T, Pals G, Van Diest PJ
Berita Kedokteran Masyarakat (BKM) Vol 23, No 3 (2007)
Publisher : Fakultas Kedokteran Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (168.017 KB) | DOI: 10.22146/bkm.3616

Abstract

Background: Breast cancer under 40 years concerns a relatively small subgroup of cases that tend to display a more aggressive phenotype. Compatible with this, early age of onset has been known as one of clinical characteristic of hereditary breast cancers associated with germline BRCA1 or BRCA1 mutations. As early onset breast cancer is frequent in Indonesia, we investigated the histopathological and immunohistochemical characteristics of early onset (< 40 years) Indonesian breast cancer patients, as such features can be used to distinguish between BRCA and non-BRCA germline mutation carriers among these young women.Method: Thirty-five formalin-fixed and paraffin-embedded tissue sections of young women (mean 36 years, range 22-40 years) who underwent surgical resection at the Department of Surgery of the Sardjito Hospital Yogyakarta were examined for pathological features, estrogen and progesterone receptor status, proliferation as determined by Ki67 labeling, EGFR and CK5/6 and the presence of HER-2/neu and p53 protein. Additionally, mutation analysis for BRCA1 and BRCA2 was performed in 30 young women. The control group consisted ofcarcinomas from women above 50 years (mean 59.02, range 50-80 years).Result: Carcinomas occurring in women aged below 40 years were more often advanced stage and higher proliferating (p=0.006). Among the early onset breast cancer patients, ductal type, grade 3, ER and HER-2/neu negativity, high Ki67 index and CK5/6 and EGFR positivity were typical for BRCA1 patients. Unfortunately, there were no typical phenotypical features for BRCA2 carriers. However, grade I and lobular cases were never BRCA1/2 germline mutated.Conclusion: Early onset Indonesian breast cancer shows increased proliferation compared to late onset patients. Within the early onset group, the strongest features pointing to a sporadic cancer seem to be grade I and lobular differentiation. Features increasing the chance of a germline BRCA1/2 mutation are CK5/6 and EGFR expression, p53 accumulation and high proliferation as measured by Ki67 labeling. This is potentially useful to optimize selection of early onset breast cancer patients for BRCA1/2 mutation testing.Keywords: breast cancer, early onset, histopathology, immunohistochemistry, BRCA1, BRCA2
Jaringan Seksual dan Perilaku Berisiko Pengguna Napza Suntik: Episode Lain Penyebaran HIV di Indonesia Ignatius Praptoraharjo, Wayne W. Wiebel, Octavery Kamil, Alfred Pach III
Berita Kedokteran Masyarakat (BKM) Vol 23, No 3 (2007)
Publisher : Fakultas Kedokteran Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (147.332 KB) | DOI: 10.22146/bkm.3617

Abstract

Background:  Although a relative late comer to the epidemic, HIV has struck Indonesia hard.  Surveillance at the Ministry of Health’s drug dependence hospital showed an escalation from 0% injecting drug users (IDUs) infected in 1997 to almost 50% infected by 2001.  As more injectors become infected, the potential for sexual transmission of HIV by IDUs increases.  Yet, little was known about IDU sexual networks, sexual partnering patterns, the nature of sexual relationships and sex risk practices.Methods:  IDUs are concentrated in major metropolitan areas across the Indonesian archipelago.  The country’s five largest cities (Jakarta, Surabaya, Medan, Bandung and Denpasar) were selected for inclusion here because they include various concentrations of IDU, potentially different, patterns of sexual networking and risk.  Participants were recruited with the assistance of local, non-governmental organizations working on HIV/AIDS interventions targeting IDUs.  A purposive sampling design sought to include subjects representing the range in known IDU characteristics at each locale.  Selection criteria included active injectors who were sexually active and 18 years of age or older.  Following informed consent, 52 willing respondents were interviewed using a semi- structured and open-ended interview guide.   Interviews were divided into narrative passages and coded as to topical content upon entry in EZText qualitative database software.Results: Indonesian IDUs were found to commonly have regular, casual and commercial sex partners.  Almost 90% were involved in a serious relationship with a spouse or girl/boy friend.  Serious relationships included emotional ties and mutual expectations and obligations.  The most common expectation was faithfulness, yet 75% of those with a regular sex partner had concurrent relations with casual and/or commercial partners.  Most male IDUs actively pursued casual and commercial relations.  Male IDUs also reported sex with transgenders and other males. Condoms were rarely used irrespective of partner category.Conclusion: The frequency of unprotected relations with a variety in types of partners suggests a high potential for the bridging of HIV to non-IDU populations in Indonesia.  Information learned about types of partnerships and relations suggest different strategies will be needed for different types of partners if a generalized epidemic is to be averted.Keywords: injecting drug users, HIV, sexual partner, risk network, intervention
Hubungan Kekerasan dalam Rumah Tangga dengan Tingkat Kecemasan pada Wanita Carla Marchira, Yosie Amylia, Mariyono Sedyo Winarso
Berita Kedokteran Masyarakat (BKM) Vol 23, No 3 (2007)
Publisher : Fakultas Kedokteran Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (481.801 KB) | DOI: 10.22146/bkm.3618

Abstract

Background: Incidence of domestic violence in DIY and Central Jawa increases every year. The women as a victim of violence have a big risk to suffered from some serious health problem, mental illness at the most. A poor marital relationship caused by domestic violence could be a social stressor and current vulnerability factors in anxiety.Objectives: The study aims at identifying the types of domestic violence, the degree of anxiety, and also the correlation between domestic violence and  anxiety among women  who have consultation in Rifka Annisa Women’s Crisis Center Yogyakarta.Methods: This study was a descriptive analytic correlation study using cross sectional design. The subject of this study were 30 women  who have consultation in Rifka Annisa Women’s Crisis Center Yogyakarta and taken by purposive sampling technique. The data was collected by means of TMAS questionnaires. Data analysis on the correlation between domestic violence and anxiety was done by using Chi Square statistic test.Results: Findings from this study showed that 43,3% subject being physically and emotionally assaulted. Most subject were experiencing moderate level of anxiety (53,3%). Chi Square test showed that there was significant difference between domestic violence and anxiety among women  who have consultation in Rifka Annisa Women’s Crisis Center Yogyakarta (X2=18.307, df=10, P<0.05).Conclusion: Most of the women  who have consultation in Rifka Annisa Women’s Crisis Center Yogyakarta had experienced more than two types of violence (80%) and 53,3% respondents report moderate level of anxiety. There are significant difference between domestic violence and anxiety among women who have consultation in Rifka Annisa Women’s Crisis Center Yogyakarta.Keywords: domestic violence, anxiety, women
Hubungan Hipertiroid dengan Aktivitas Kerja pada Wanita Usia Subur Sri Supadmi, Ova Emilia, Hari Kusnanto
Berita Kedokteran Masyarakat (BKM) Vol 23, No 3 (2007)
Publisher : Fakultas Kedokteran Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (151.033 KB) | DOI: 10.22146/bkm.3619

Abstract

Background: Based on disorder mapping due to Iodine deficiency in 1998 and 2003, elimination of Iodine deficiency in household by consuming minimally 90 percent Iodine salt and giving Iodine oil capsule to fertile women in endemic Iodine deficiency, medium to severe, had been carried out. Evaluation of Iodine in urine appeared related to hyperthyroid cases, and a number of people were in critical Iodine status. Hyperthyroid especially for fertile women may cause fatigue and led to low working activity.Objective: To find out correlation between thyroid and working activity of fertile women in endemic Iodine deficiency.Method: The study was a cross-sectional design using two samples in Magelang District. The samples were 100 fertile women who were divided into two groups, namely hyperthyroid (50 persons) and norm thyroid group (50 persons) taken by using systematic sampling.Result: Bivariate analysis showed significant relationship between hyperthyroid and working activity (RP=4.10; 95%Cl; 2.32 - 7.24). Using stratification analysis it was found that hyperthyroid were higher among women with hormonal contraceptive (RP=6.45; 95%Cl; 2.55 - 16.34) and consumed Iodine capsule (RP=4.73; 95%Cl; 2.37 - 9.43).Conclusion: There was a significant correlation between hyperthyroid and working activity of fertile women. Hyperthyroid women tend to have lower working activity (four times lower) than norm thyroid women. The modified effects were hormonal contraceptive and Iodine capsule factors. The factors not affecting the correlation between hyperthyroid and working activity of fertile women were age, Body Mass Index (BMI) and Iodine salt consumption.Keywords: Iodine deficiency, hyperthyroid, working activity
Faktor Risiko terjadinya Cedera pada Anak Usia Sekolah Dasar Susy Kuschithawati, Rahadyan Magetsari, Nawi Ng
Berita Kedokteran Masyarakat (BKM) Vol 23, No 3 (2007)
Publisher : Fakultas Kedokteran Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (790.968 KB) | DOI: 10.22146/bkm.3620

Abstract

Background: Every year many children all over the world become disabled or die because of injury. It is estimated that 98% of child mortality is caused by injury, and this mostly happens in low and middle income countries. Injury may happen accidentally or intentionally and internally (from the children themselves) or externally (from environmental factors).Objective: The objective of the study was to identify the seriousness and types of injury and risk factors of injury occurrence among elementary school children at Yogyakarta Municipality.Methods: The study used school-based cross sectional design and was conducted at 28 elementary schools of Yogyakarta municipality with as many as 4690 children of grade I – VI as subject of the study. Samples were taken using multistage cluster sampling technique. Dependent variables consisted of injury that took place at schools, home and the surrounding and absence from school, whereas independent variables consisted of age and sex of children, age of mothers, social and economic status, home environment and time. Research instruments used were questionnaires to get data of injury risk factors and impact of injury and observation sheets to assessschool environment.Results: Injury prevalence was as much as 42.56% (mild injury 36,89% and severe injury 5,7%) . Factors related to injury occurrence among elementary school children were sex (OR=1.31; 95% CI 1.16 – 1.47) and home environment (OR=2.76; 95% CI 1.36 – 6.62). Types of injury that often happened to elementary school children were scratches, bruises, sprains, bites, flesh wounds burns, road accidents, broken bone and small particles infiltration.Conclusion: Home environment was an important factor of injury occurrence among elementary school children. Therefore preventive action had to be taken by improving home and environment security, and alerts of parents in order that occurrence of injury could be avoided. Sex of children was also an important factor of cause for injury occurrence among elementary school children.Keywords: injury among children, risk factors, prevalence
Faktor-Faktor Risiko Pasien Diabetes Melitus Zahtamal Fifia Chandra, Suyanto, Tuti Restuastuti
Berita Kedokteran Masyarakat (BKM) Vol 23, No 3 (2007)
Publisher : Fakultas Kedokteran Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (142.709 KB) | DOI: 10.22146/bkm.3621

Abstract

Background: Diabetes Mellitus (DM) remains a health problem in Indonesia as well as in many other countries. According to Medical Record of Regional Hospital of Arifin Achmad Riau Province, the incidence of   DM still high among endocrine, nutrition and metabolic diseases. About 188 cases of DM had recorded in the year 2003, 221 case in the year 2004 and 158 case in 2005. One of the strategies to decrease and manage this disease is by the screening risk factors besides an adequate therapy.Objective: To assess the risk factors for DM such as age, family history of diabetes, dietary habits, knowledge about DM and type of personality amongst patient with DM.Methods: A case-control study was conducted on 154 patient from Regional Hospital of Arifin Achmad Riau Province. Cases included 79 patient identified as a DM and controls include 75 patient who did not suffer DM. Data of age, family history of diabetes, dietary habits and type of personality was taken by questionnaire diabetes risk factors. Data of risk factors was obtained by a questionnaire given to 2 groups (case and control group).Results: There was association between several risk factors and incidence of DM, include; age [odds ratio (OR) = 6, 45; p= 0,000, PAR= 0, 84], family history of DM (OR= 3, 75; p = 0,001, PAR= 0, 73), knowledge about DM (OR= 0, 13; p = 0,000, PAR= -6, 7/as a protective factor). However, there was evidence of a no association between type of personality and incidence of DM (OR= 50.4; p = 0,479, PAR= 0, 98) and also dietary habits (OR= 1, 06; p = 0,896, PAR= 0 06)Conclusion: These findings suggest a complex interaction among age factor, family history of diabetes, knowledge about DM, dietary habits and type of personality with the incidence of DM in Regional Hospital of Arifin Achmad Riau Province.Keywords: risk factors, diabetes mellitus, type of personality
Karakteristik, Pengetahuan, dan Sikap Ibu terhadap Penyakit Demam Berdarah Dengue Herke J. O. Sigarlaki
Berita Kedokteran Masyarakat (BKM) Vol 23, No 3 (2007)
Publisher : Fakultas Kedokteran Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (170.177 KB) | DOI: 10.22146/bkm.3622

Abstract

Background: Dengue Haemorragic Fever (DHF) is an illness that we can find in children an adult with the main simptoms such as fever, myalgia which is could be worst after 2 days. Prevention of DHF is organized with health promotion and treatment education for doctors and paramedic and also the involvement of people to eliminate the mosquitos, so we hope at the future the prevalence of DHF could be decreased.Objective: To get information about the distribution of characteristic and behavior of mother toward DHF. The characteristics include age, occupation, and education. While behaviors includes attitude, knowledge, and practice.Method:  We use a cross sectional descriptive for study with a questioner and check list as the instrument.Result: From this study we found that 46,4 % of the subject lacked of knowledge about DHF ; 42,5% lacked of knowledge as well as low education. 44,1% lack of knowledge with good attitudeConclusion: The level of education contributes in determining the level of knowledge while knowledge does not always determine that person’s attitude.Keywords: Dengue Haemorragic Fever (DHF), characteristic, knowledge, behavior, attitude

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